iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-068092

Ensembl Protein ID

ENSMLUP00000002767.2

UniProt Accession

G1NZ92; G1NZ92_MYOLU

Genbank Protein ID

ENSMLUP00000002767

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02037211

Gene Name

DDX58

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000003041.2	ENSMLUT00000003044.2	ENSMLUP00000002767.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	6.60e-48	161.2	2	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 2    deeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL..vqkegWfrefl 73
           + e r+ l +++d+v k+Ld+t++l+ y+s++++e e+++i+a++++kg m+aa+l+Lk+L  +q+egWfr+fl
   Q: 2    TAEERRNLHAFRDYVTKILDPTYILS-YMSPWFKEDEVQYIQAEKNNKGVMEAATLFLKFLleLQEEGWFRGFL 74
           5678999*******************.*********************************************96 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MTAEERRNLH AFRDYVTKIL DPTYILSYMS PWFKEDEVQY IQAEKNNKGV MEAATLFLKF 60
LLELQEEGWF RGFLDALHHA GYSGLYEAIE SWDFHKIEKL EEHRSLLRRL QPEFKTRINP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGGCCG AGGAGCGGCG GAATCTGCAC GCCTTCCGGG ACTATGTCAC CAAGATCCTG 60
GACCCTACCT ACATCCTGAG CTACATGTCC CCCTGGTTTA AGGAGGGTGA GTGGTCGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005923--C:bicellular tight junction
GO:0005829--C:cytosol
GO:0032587--C:ruffle membrane
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0009597--P:detection of virus
GO:0045087--P:innate immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0032725--P:positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030334--P:regulation of cell migration
GO:0043330--P:response to exogenous dsRNA
GO:0039529--P:RIG-I signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001898	Ailuropoda melanoleuca	82.30	0.00e+00	1530.00
IUUC-Apl-003966	Anas platyrhynchos	53.18	0.00e+00	925.00
IUUC-Aca-004499	Anolis carolinensis	46.80	0.00e+00	800.00
IUUC-Ame-011950	Astyanax mexicanus	43.72	0.00e+00	714.00
IUUC-Bta-012489	Bos taurus	81.05	0.00e+00	1489.00
IUUC-Cel-018230	Caenorhabditis elegans	30.10	9.00e-70	258.00
IUUC-Cja-018716	Callithrix jacchus	80.13	0.00e+00	1496.00
IUUC-Cfa-020269	Canis familiaris	84.05	0.00e+00	1589.00
IUUC-Cpo-022507	Cavia porcellus	73.64	0.00e+00	1365.00
IUUC-Csa-024209	Chlorocebus sabaeus	79.91	0.00e+00	1503.00
IUUC-Cho-025104	Choloepus hoffmanni	74.65	0.00e+00	1186.00
IUUC-Cin-025792	Ciona intestinalis	32.24	2.00e-82	300.00
IUUC-Dno-028954	Dasypus novemcinctus	78.41	0.00e+00	1425.00
IUUC-Eca-034039	Equus caballus	82.28	0.00e+00	1537.00
IUUC-Eeu-035009	Erinaceus europaeus	71.00	0.00e+00	942.00
IUUC-Fca-036169	Felis catus	84.91	0.00e+00	1599.00
IUUC-Fal-037579	Ficedula albicollis	55.64	0.00e+00	946.00
IUUC-Ggo-045318	Gorilla gorilla	78.89	0.00e+00	1380.00
IUUC-Hsa-046671	Homo sapiens	81.63	0.00e+00	1506.00
IUUC-Itr-047996	Ictidomys tridecemlineatus	75.30	0.00e+00	1395.00
IUUC-Lch-050461	Latimeria chalumnae	50.60	0.00e+00	870.00
IUUC-Loc-052582	Lepisosteus oculatus	47.33	0.00e+00	823.00
IUUC-Laf-054324	Loxodonta africana	80.62	0.00e+00	1463.00
IUUC-Mcc-055390	Macaca mulatta	79.59	0.00e+00	1488.00
IUUC-Meu-056365	Macropus eugenii	64.27	9.00e-127	447.00
IUUC-Mmr-061407	Microcebus murinus	80.77	0.00e+00	1543.00
IUUC-Mmu-063939	Mus musculus	74.01	0.00e+00	1368.00
IUUC-Mpu-066226	Mustela putorius furo	82.10	0.00e+00	1447.00
IUUC-Opr-070246	Ochotona princeps	75.38	4.00e-148	518.00
IUUC-Oan-072742	Ornithorhynchus anatinus	60.15	0.00e+00	958.00
IUUC-Ocu-073959	Oryctolagus cuniculus	73.31	0.00e+00	1393.00
IUUC-Oga-089173	Otolemur garnettii	80.86	0.00e+00	1486.00
IUUC-Oar-089369	Ovis aries	79.66	0.00e+00	1459.00
IUUC-Ptr-091032	Pan troglodytes	81.63	0.00e+00	1506.00
IUUC-Pan-092383	Papio anubis	79.91	0.00e+00	1496.00
IUUC-Psi-093432	Pelodiscus sinensis	57.22	0.00e+00	1075.00
IUUC-Pma-094367	Petromyzon marinus	41.10	8.00e-113	400.00
IUUC-Pab-098416	Pongo abelii	81.50	0.00e+00	1407.00
IUUC-Pca-101006	Procavia capensis	78.73	0.00e+00	658.00
IUUC-Pva-102966	Pteropus vampyrus	86.08	0.00e+00	1594.00
IUUC-Pgr-103529	Puccinia graminis	26.23	2.00e-23	105.00
IUUC-Rno-105059	Rattus norvegicus	73.08	0.00e+00	880.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	28.28	4.00e-03	38.50
IUUC-Sar-113202	Sorex araneus	68.01	0.00e+00	1052.00
IUUC-Ssc-116120	Sus scrofa	80.41	0.00e+00	1454.00
IUUC-Tgu-117314	Taeniopygia guttata	54.30	0.00e+00	968.00
IUUC-Tsy-119453	Tarsius syrichta	80.19	0.00e+00	851.00
IUUC-Tre-122194	Trichoderma reesei	26.01	1.00e-17	86.30
IUUC-Ttr-128421	Tursiops truncatus	78.30	0.00e+00	1219.00
IUUC-Vpa-130602	Vicugna pacos	80.52	0.00e+00	1415.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence