iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066226

Ensembl Protein ID

ENSMPUP00000004286.1

UniProt Accession

M3XYY5; M3XYY5_MUSPF

Genbank Protein ID

ENSMPUP00000004286

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01063316

Gene Name

DDX58

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000004319.1	ENSMPUT00000004362.1	ENSMPUP00000004286.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	2.30e-33	114.6	149	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 3    eeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL..vqkegWfrefl 73
           eeyr ll++lq++++++  ++d+l  ++s +l+ +e+e+i++ +++kg m++ae+++++L  ++ke+W+++++
   Q: 149  EEYRSLLKRLQPEFKTTVNPKDILP-EISQCLISQECEEIIQVCSNKGLMAGAEKMVECLlrSDKENWPKTLK 220
           9************************.********************************************985 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MGSQQPPGSP LSREEGEAPP PAPAPEGRRR SRRVRLRGSC RHRPSFLGRR ELGTSAPAGT 60
ASVSEIMASA AKEFKMDNFS PKADEVQHIQ AEKNNKGTME AASLFLKFLL ERQEEGWFRG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTAAGGA GGCGGCGGCT GCCCGCGGGA ACGGAGGGAA ACTGCAGGCC CTAGAGTAAC 60
AACCGGGGCG GCGGCTGCCG AGCGGCGGCG GCCATCTTTC AGCCGGGCAC AAGCGCCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005923--C:bicellular tight junction
GO:0005829--C:cytosol
GO:0032587--C:ruffle membrane
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0009597--P:detection of virus
GO:0045087--P:innate immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0032725--P:positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030334--P:regulation of cell migration
GO:0043330--P:response to exogenous dsRNA
GO:0039529--P:RIG-I signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001898	Ailuropoda melanoleuca	89.29	0.00e+00	1499.00
IUUC-Apl-003966	Anas platyrhynchos	51.84	0.00e+00	849.00
IUUC-Aca-004499	Anolis carolinensis	45.56	0.00e+00	686.00
IUUC-Ame-011950	Astyanax mexicanus	42.89	0.00e+00	635.00
IUUC-Bta-012489	Bos taurus	81.49	0.00e+00	1352.00
IUUC-Cel-018230	Caenorhabditis elegans	30.71	8.00e-69	255.00
IUUC-Cja-018716	Callithrix jacchus	78.14	0.00e+00	1337.00
IUUC-Cfa-020269	Canis familiaris	88.21	0.00e+00	1518.00
IUUC-Cpo-022507	Cavia porcellus	73.65	0.00e+00	1236.00
IUUC-Csa-024209	Chlorocebus sabaeus	79.65	0.00e+00	1350.00
IUUC-Cho-025104	Choloepus hoffmanni	72.24	0.00e+00	1081.00
IUUC-Cin-025792	Ciona intestinalis	32.63	1.00e-77	284.00
IUUC-Dno-028954	Dasypus novemcinctus	77.09	0.00e+00	1270.00
IUUC-Eca-034039	Equus caballus	82.47	0.00e+00	1388.00
IUUC-Eeu-035009	Erinaceus europaeus	68.62	0.00e+00	863.00
IUUC-Fca-036169	Felis catus	88.21	0.00e+00	1510.00
IUUC-Fal-037579	Ficedula albicollis	52.28	0.00e+00	856.00
IUUC-Fso-038398	Fusarium solani	24.33	3.00e-19	91.70
IUUC-Ggo-045318	Gorilla gorilla	77.57	0.00e+00	1290.00
IUUC-Hsa-046671	Homo sapiens	79.88	0.00e+00	1322.00
IUUC-Itr-047996	Ictidomys tridecemlineatus	75.12	0.00e+00	1244.00
IUUC-Lch-050461	Latimeria chalumnae	49.94	0.00e+00	831.00
IUUC-Loc-052582	Lepisosteus oculatus	47.17	0.00e+00	768.00
IUUC-Laf-054324	Loxodonta africana	78.08	0.00e+00	1274.00
IUUC-Mcc-055390	Macaca mulatta	78.47	0.00e+00	1330.00
IUUC-Meu-056365	Macropus eugenii	60.40	7.00e-120	425.00
IUUC-Mvi-060497	Microbotryum violaceum	25.71	6.00e-25	110.00
IUUC-Mmr-061407	Microcebus murinus	79.53	0.00e+00	1363.00
IUUC-Mmu-063939	Mus musculus	73.58	0.00e+00	1217.00
IUUC-Mlu-068092	Myotis lucifugus	82.10	0.00e+00	1341.00
IUUC-Nfi-068405	Neosartorya fischeri	26.79	1.00e-13	73.20
IUUC-Opr-070246	Ochotona princeps	66.07	0.00e+00	657.00
IUUC-Oan-072742	Ornithorhynchus anatinus	58.11	0.00e+00	871.00
IUUC-Ocu-073959	Oryctolagus cuniculus	74.27	0.00e+00	1271.00
IUUC-Oga-089173	Otolemur garnettii	78.47	0.00e+00	1315.00
IUUC-Oar-089369	Ovis aries	81.25	0.00e+00	1320.00
IUUC-Ptr-091032	Pan troglodytes	79.88	0.00e+00	1322.00
IUUC-Pan-092383	Papio anubis	79.29	0.00e+00	1341.00
IUUC-Psi-093432	Pelodiscus sinensis	55.58	0.00e+00	947.00
IUUC-Pma-094367	Petromyzon marinus	39.93	4.00e-102	365.00
IUUC-Pab-098416	Pongo abelii	79.83	0.00e+00	1293.00
IUUC-Pca-101006	Procavia capensis	78.99	0.00e+00	660.00
IUUC-Pva-102966	Pteropus vampyrus	83.14	0.00e+00	1407.00
IUUC-Pgr-103529	Puccinia graminis	26.76	2.00e-26	115.00
IUUC-Rno-105059	Rattus norvegicus	73.05	0.00e+00	816.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	31.63	7.00e-05	44.30
IUUC-Sar-113202	Sorex araneus	66.85	0.00e+00	968.00
IUUC-Ssc-116120	Sus scrofa	80.30	0.00e+00	1349.00
IUUC-Tgu-117314	Taeniopygia guttata	53.28	0.00e+00	867.00
IUUC-Tsy-119453	Tarsius syrichta	78.87	0.00e+00	773.00
IUUC-Tre-122194	Trichoderma reesei	25.38	2.00e-17	85.10
IUUC-Ttr-128421	Tursiops truncatus	76.62	0.00e+00	1120.00
IUUC-Vpa-130602	Vicugna pacos	79.41	0.00e+00	1314.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence