iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073443

UUCD1 version

UUC-OrA-00036

Ensembl Protein ID

ENSOANP00000010564.2

UniProt Accession

F6Q439; F6Q439_ORNAN

Protein Name

Uncharacterized protein

Gene Name

SOCS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000006625.2	ENSOANT00000010566.2	ENSOANP00000010564.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	4.40e-15	55.5	146	190

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++l ++ +SLqhLCRl+I++c+ +     i++LPLP +LkdYL++++yq
   Q: 146  TKPLYTSTPSLQHLCRLTINKCTSK-----IWELPLPTRLKDYLKEYQYQ 190
           67889999***************99.....8****************986 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MTLRCPQPRA GSDGSEGAAD EQPPEPPGLA KAMRELTHTG WYWGNMTVNE AKEKLKDAPE 60
GTFLIRDSSH SDYLLTISVK TSAGPTNLRI EYQDGKFRLD SIICIKSRLK QFDSVAHLIE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCCGAGGGG CCGGGACGAG CCGGGACAGT AGCTGCCGGC GCCGCCCCCG GGGCCGCCCC 60
CCGGGCTTGC CCCCCGGCCC CATGACCCTG CGCTGCCCGC AGCCCCGCGC CGGCAGCGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0060396--P:growth hormone receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth
GO:0032355--P:response to estradiol

KEGG

oaa:100079417

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	78.28	5.00e-86	309.00
IUUC-Apl-003484	Anas platyrhynchos	82.35	5.00e-75	272.00
IUUC-Aca-004253	Anolis carolinensis	75.46	3.00e-74	270.00
IUUC-Ame-011267	Astyanax mexicanus	62.35	5.00e-61	226.00
IUUC-Bta-013183	Bos taurus	77.50	9.00e-83	298.00
IUUC-Cja-018862	Callithrix jacchus	78.28	3.00e-82	296.00
IUUC-Cfa-020226	Canis familiaris	77.89	5.00e-82	295.00
IUUC-Cpo-022414	Cavia porcellus	78.79	2.00e-84	304.00
IUUC-Csa-023758	Chlorocebus sabaeus	77.78	5.00e-84	302.00
IUUC-Cho-024471	Choloepus hoffmanni	82.24	7.00e-68	248.00
IUUC-Cin-025413	Ciona intestinalis	34.34	2.00e-20	92.80
IUUC-Csv-026247	Ciona savignyi	34.94	3.00e-21	95.90
IUUC-Dre-028288	Danio rerio	57.51	4.00e-63	233.00
IUUC-Dno-029036	Dasypus novemcinctus	78.79	6.00e-87	312.00
IUUC-Dor-030447	Dipodomys ordii	88.74	2.00e-79	286.00
IUUC-Dme-031876	Drosophila melanogaster	30.29	6.00e-19	89.40
IUUC-Ete-033023	Echinops telfairi	76.77	5.00e-88	315.00
IUUC-Fca-036469	Felis catus	78.28	5.00e-81	292.00
IUUC-Fal-036642	Ficedula albicollis	76.33	1.00e-74	271.00
IUUC-Gmo-039331	Gadus morhua	60.36	6.00e-36	141.00
IUUC-Gga-040809	Gallus gallus	81.13	1.00e-76	277.00
IUUC-Gac-041398	Gasterosteus aculeatus	58.29	5.00e-60	223.00
IUUC-Ggo-045341	Gorilla gorilla	78.79	2.00e-82	297.00
IUUC-Hsa-046557	Homo sapiens	78.28	2.00e-90	323.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	72.12	1.00e-81	294.00
IUUC-Lch-050160	Latimeria chalumnae	63.01	3.00e-51	193.00
IUUC-Loc-051825	Lepisosteus oculatus	59.38	2.00e-62	231.00
IUUC-Laf-053560	Loxodonta africana	75.50	5.00e-80	289.00
IUUC-Mcc-055890	Macaca mulatta	77.78	3.00e-81	293.00
IUUC-Meu-056218	Macropus eugenii	80.30	2.00e-93	333.00
IUUC-Mga-059755	Meleagris gallopavo	82.89	9.00e-75	271.00
IUUC-Mvi-060489	Microbotryum violaceum	28.33	4.70e+00	25.00
IUUC-Mmr-061387	Microcebus murinus	77.27	2.00e-82	297.00
IUUC-Mdo-062383	Monodelphis domestica	88.20	2.00e-93	333.00
IUUC-Mmu-063443	Mus musculus	77.78	1.00e-83	301.00
IUUC-Mpu-066459	Mustela putorius furo	77.78	7.00e-81	292.00
IUUC-Mlu-068040	Myotis lucifugus	78.79	6.00e-87	312.00
IUUC-Nle-069016	Nomascus leucogenys	76.14	1.00e-82	297.00
IUUC-Opr-071087	Ochotona princeps	75.25	4.00e-84	303.00
IUUC-Ont-072340	Oreochromis niloticus	57.75	1.00e-60	225.00
IUUC-Ocu-074539	Oryctolagus cuniculus	77.16	8.00e-80	288.00
IUUC-Ola-087004	Oryzias latipes	58.86	1.00e-55	207.00
IUUC-Oga-088438	Otolemur garnettii	77.78	6.00e-84	302.00
IUUC-Oar-089932	Ovis aries	78.50	2.00e-83	300.00
IUUC-Ptr-091037	Pan troglodytes	78.79	2.00e-82	297.00
IUUC-Pan-092767	Papio anubis	78.79	6.00e-82	295.00
IUUC-Psi-093099	Pelodiscus sinensis	83.65	1.00e-78	284.00
IUUC-Pma-094671	Petromyzon marinus	44.52	8.00e-36	142.00
IUUC-Pfo-097073	Poecilia formosa	51.67	2.00e-55	208.00
IUUC-Pab-098319	Pongo abelii	78.79	4.00e-87	313.00
IUUC-Pca-101117	Procavia capensis	77.27	1.00e-81	294.00
IUUC-Pva-102117	Pteropus vampyrus	78.28	2.00e-80	290.00
IUUC-Rno-105913	Rattus norvegicus	76.77	3.00e-82	296.00
IUUC-Sha-106500	Sarcophilus harrisii	82.56	1.00e-92	331.00
IUUC-Ssc-115252	Sus scrofa	79.29	2.00e-85	307.00
IUUC-Tgu-117524	Taeniopygia guttata	80.50	2.00e-74	270.00
IUUC-Tsy-119335	Tarsius syrichta	85.43	7.00e-78	281.00
IUUC-Tni-120263	Tetraodon nigroviridis	56.70	7.00e-59	219.00
IUUC-Tca-121866	Theobroma cacao	41.46	4.60e-02	31.60
IUUC-Tbe-127915	Tupaia belangeri	78.00	5.00e-81	292.00
IUUC-Ttr-128372	Tursiops truncatus	79.29	2.00e-85	307.00
IUUC-Vpa-130422	Vicugna pacos	88.74	3.00e-79	286.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence