iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071910

Ensembl Protein ID

ENSONIP00000004004.1

UniProt Accession

I3J564; I3J564_ORENI

Genbank Protein ID

ENSONIP00000004004

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Genbank Nucleotide ID

AERX01013894

Gene Name

dcun1d2b; dcun1d2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000003192.1	ENSONIT00000004005.1	ENSONIP00000004004.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	8.80e-89	297.0	60	247
UBD/Alpha-Helix/UBA	7.30e-07	29.5	7	45

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 1    vskkkleelferYkdpqed.ligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktlesel 88
           v++kkle+l++rYkdpq++ +igi+g+++fc+dl++dp+++++Lv+awk++aat+cefsr+efldg+ +lgcds ekl++ l++le+el
   Q: 60   VDRKKLEQLYNRYKDPQDEnKIGIDGIQQFCDDLTLDPASMSILVVAWKFRAATQCEFSRKEFLDGMAELGCDSPEKLKAILPRLEQEL 148
           589**************999********************************************************************* PP
   S: 89   kdeqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaW 177
           kd  kfkd+Y+f+f+fak++gqk+ldl++a+a+w+L+l++r fk+ld+w++fL e++k+si++DtWnllL+f ++ia+d+snYdeegaW
   Q: 149  KDSGKFKDFYQFTFSFAKNPGQKGLDLEMAVAYWNLVLTGR-FKFLDLWNRFLLEHHKRSIPRDTWNLLLDFGNMIADDMSNYDEEGAW 236
           *****************************************.*********************************************** PP
   S: 178  PvliDefveyl 188
           PvliD+fve++
   Q: 237  PVLIDDFVEFA 247
           *********97 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdre...ealqaLraannnleaAveyLl 39
           +++dk++q+++  F++    +a+ +L+++++ le+A+++++
   Q: 7    SQKDKVRQFMS--FTQAgerTAVYCLAQNDWKLEVATDNYF 45
           699********..7777777*******************99 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

QHKLKSSQKD KVRQFMSFTQ AGERTAVYCL AQNDWKLEVA TDNYFQNPDL YYKESMKTSV 60
DRKKLEQLYN RYKDPQDENK IGIDGIQQFC DDLTLDPASM SILVVAWKFR AATQCEFSRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCACAAGC TGAAGTCATC ACAGAAGGAC AAAGTTCGGC AGTTCATGTC CTTCACGCAG 60
GCAGGCGAAA GGACAGCTGT GTACTGCCTG GCACAGAATG ACTGGAAACT AGAAGTCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR011992--EF-hand-dom_pair
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011553	Astyanax mexicanus	96.27	4.00e-140	489.00
IUUC-Dse-031365	Dothistroma septosporum	26.56	2.00e-26	112.00
IUUC-Dme-032197	Drosophila melanogaster	63.71	2.00e-93	335.00
IUUC-Fox-037884	Fusarium oxysporum	32.89	2.00e-17	82.00
IUUC-Fso-038150	Fusarium solani	31.86	1.00e-20	94.00
IUUC-Gac-041853	Gasterosteus aculeatus	93.44	2.00e-146	511.00
IUUC-Hsa-046994	Homo sapiens	84.05	2.00e-134	471.00
IUUC-Mac-065016	Musa acuminata	47.31	5.00e-43	167.00
IUUC-Ptr-091595	Pan troglodytes	84.44	4.00e-134	470.00
IUUC-Pan-092825	Papio anubis	85.60	8.00e-136	476.00
IUUC-Pyt-104428	Pyrenophora triticirepentis	31.10	1.00e-28	120.00
IUUC-Tru-118119	Takifugu rubripes	93.41	2.00e-145	508.00
IUUC-Tni-120315	Tetraodon nigroviridis	92.64	4.00e-145	506.00
IUUC-Tre-121986	Trichoderma reesei	26.16	2.00e-21	96.70
IUUC-Tvi-122607	Trichoderma virens	31.68	3.00e-28	119.00
IUUC-Yli-134595	Yarrowia lipolytica	35.27	3.00e-38	151.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence