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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Rno-105118
UUCD1 version UUC-RaN-00165
Ensembl Protein ID ENSRNOP00000053769.4
UniProt Accession D3ZH46; D3ZH46_RAT
Genbank Protein ID ENSRNOP00000053769
Protein Name Inhibitor of Bruton tyrosine kinase
Genbank Nucleotide ID AABR07070954
Gene Name Ibtk
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000027728.7 ENSRNOT00000056930.5 ENSRNOP00000053769.4
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
RAID2
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 6.00e-25 87.8 768 831
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 2    Dvilv.vggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           Dv+ + v+g+ef++hk+vL+a+ ++F+++++  + e  s    e+  +q+e ++++l++lYt+++
   Q: 768  DVTMKsVDGKEFPCHKCVLCARLEYFHSMLSRSWIEASSCAALEMP-IQAEILKVILDYLYTDEA 831
           56665156***************************99999999999.***************986 PP
   
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MDSAAPDCTA KCRSLKHALD VLSVITKGSE RQIKIFLSSY CYNAATVKDA FGRNALHLVS 60
SCGKKAVLDW LIEKGVDLLV KDKESGWTAL HRSIFYGHIN CVWSLLKHGV SLYMQDKEGL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105118|E3,BTB_Other|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGATTCTG CCGCCCCCGA CTGCACGGCC AAGTGCAGGT CCCTGAAGCA CGCTCTGGAT 60
GTCCTTTCTG TGATAACAAA GGGCAGTGAG AGGCAGATCA AGATCTTTCT CTCCAGTTAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105118|E3,BTB_Other|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR000210--BTB/POZ_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
IPR011333--SKP1/BTB/POZ
PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50097--BTB
PS50012--RCC1_3
Pfam

PF12796--Ank_2
PF00651--BTB
PF00415--RCC1
PRINTS

PR00633--RCCNDNSATION
SMART

SM00248--ANK
SM00225--BTB
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0030292--F:protein tyrosine kinase inhibitor activity
GO:0051209--P:release of sequestered calcium ion into cytosol
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000696 Aegilops tauschii 35.42 1.00e-34 142.00
IUUC-Aml-001765 Ailuropoda melanoleuca 82.74 0.00e+00 2172.00
IUUC-Apl-003868 Anas platyrhynchos 68.26 0.00e+00 1841.00
IUUC-Aca-004897 Anolis carolinensis 62.89 0.00e+00 1592.00
IUUC-Ago-007942 Ashbya gossypii 24.10 4.00e-11 64.30
IUUC-Acl-008353 Aspergillus clavatus 26.55 9.00e-27 116.00
IUUC-Afl-008409 Aspergillus flavus 25.76 3.00e-30 128.00
IUUC-Afu-008944 Aspergillus fumigatus 24.90 4.00e-28 121.00
IUUC-Ani-009309 Aspergillus nidulans 25.94 2.00e-26 115.00
IUUC-Ang-009872 Aspergillus niger 29.43 8.00e-33 136.00
IUUC-Aor-010054 Aspergillus oryzae 25.76 3.00e-30 128.00
IUUC-Ate-010319 Aspergillus terreus 24.23 2.00e-09 58.90
IUUC-Ame-010972 Astyanax mexicanus 55.72 0.00e+00 1377.00
IUUC-Bgr-012036 Blumeria graminis 25.98 2.00e-22 102.00
IUUC-Bta-012491 Bos taurus 82.57 0.00e+00 2189.00
IUUC-Bci-013874 Botrytis cinerea 26.59 5.00e-29 124.00
IUUC-Bdi-014094 Brachypodium distachyon 36.22 1.00e-35 145.00
IUUC-Cja-019928 Callithrix jacchus 82.88 0.00e+00 2227.00
IUUC-Cfa-021191 Canis familiaris 83.38 0.00e+00 2249.00
IUUC-Cpo-021893 Cavia porcellus 78.04 0.00e+00 1329.00
IUUC-Csa-023410 Chlorocebus sabaeus 83.53 0.00e+00 2244.00
IUUC-Cho-024939 Choloepus hoffmanni 74.05 0.00e+00 1733.00
IUUC-Cin-025713 Ciona intestinalis 32.63 8.00e-138 484.00
IUUC-Cgl-026577 Colletotrichum gloeosporioides 24.38 1.00e-17 86.70
IUUC-Cne-026961 Cryptococcus neoformans 31.91 2.00e-17 85.10
IUUC-Cme-027274 Cyanidioschyzon merolae 30.61 1.00e-09 59.30
IUUC-Dre-027465 Danio rerio 53.25 0.00e+00 1322.00
IUUC-Dno-029885 Dasypus novemcinctus 82.64 0.00e+00 2227.00
IUUC-Dor-030105 Dipodomys ordii 85.53 0.00e+00 889.00
IUUC-Dse-031213 Dothistroma septosporum 26.73 1.00e-32 135.00
IUUC-Dme-031915 Drosophila melanogaster 29.44 7.00e-64 239.00
IUUC-Ete-033002 Echinops telfairi 70.21 0.00e+00 1763.00
IUUC-Eca-034271 Equus caballus 83.09 0.00e+00 2236.00
IUUC-Eeu-034921 Erinaceus europaeus 75.76 0.00e+00 1970.00
IUUC-Fca-036135 Felis catus 81.25 0.00e+00 2218.00
IUUC-Fal-036815 Ficedula albicollis 67.82 0.00e+00 1708.00
IUUC-Fox-037821 Fusarium oxysporum 27.22 1.00e-22 102.00
IUUC-Fso-038316 Fusarium solani 28.50 7.00e-26 113.00
IUUC-Gmo-038841 Gadus morhua 54.08 0.00e+00 1347.00
IUUC-Ggr-040105 Gaeumannomyces graminis 28.46 6.00e-26 114.00
IUUC-Gga-040756 Gallus gallus 68.33 0.00e+00 1772.00
IUUC-Gac-041957 Gasterosteus aculeatus 55.63 0.00e+00 1382.00
IUUC-Ggo-044737 Gorilla gorilla 80.87 0.00e+00 2147.00
IUUC-Hsa-046756 Homo sapiens 83.83 0.00e+00 2247.00
IUUC-Itr-048204 Ictidomys tridecemlineatus 82.50 0.00e+00 2207.00
IUUC-Lch-050082 Latimeria chalumnae 72.78 3.00e-79 287.00
IUUC-Lpe-050709 Leersia perrieri 31.78 5.00e-36 147.00
IUUC-Loc-052669 Lepisosteus oculatus 60.43 0.00e+00 1541.00
IUUC-Lma-053227 Leptosphaeria maculans 27.74 2.00e-31 132.00
IUUC-Laf-053898 Loxodonta africana 83.16 0.00e+00 2181.00
IUUC-Mcc-055614 Macaca mulatta 83.46 0.00e+00 2234.00
IUUC-Meu-056803 Macropus eugenii 54.92 0.00e+00 884.00
IUUC-Mor-056973 Magnaporthe oryzae 24.72 1.00e-27 119.00
IUUC-Mpo-057627 Magnaporthe poae 28.13 6.00e-25 110.00
IUUC-Mla-058948 Melampsora laricipopulina 30.61 8.00e-27 117.00
IUUC-Mga-059344 Meleagris gallopavo 67.33 0.00e+00 1729.00
IUUC-Mvi-060265 Microbotryum violaceum 27.37 6.00e-24 107.00
IUUC-Mmr-061025 Microcebus murinus 83.97 0.00e+00 2215.00
IUUC-Mdo-061884 Monodelphis domestica 72.23 0.00e+00 1894.00
IUUC-Mmu-063492 Mus musculus 91.57 0.00e+00 2388.00
IUUC-Mac-065442 Musa acuminata 29.30 1.00e-32 135.00
IUUC-Mpu-065714 Mustela putorius furo 82.57 0.00e+00 2194.00
IUUC-Mlu-068229 Myotis lucifugus 80.89 0.00e+00 2125.00
IUUC-Nfi-068585 Neosartorya fischeri 25.71 2.00e-29 125.00
IUUC-Ncr-068789 Neurospora crassa 29.23 4.00e-22 101.00
IUUC-Nle-070017 Nomascus leucogenys 83.75 0.00e+00 2251.00
IUUC-Opr-070430 Ochotona princeps 76.39 0.00e+00 1546.00
IUUC-Ont-071686 Oreochromis niloticus 57.47 0.00e+00 1450.00
IUUC-Oan-073539 Ornithorhynchus anatinus 70.91 0.00e+00 1692.00
IUUC-Ocu-074076 Oryctolagus cuniculus 82.94 0.00e+00 2198.00
IUUC-Oba-075204 Oryza barthii 31.77 8.00e-36 146.00
IUUC-Obr-076797 Oryza brachyantha 32.87 4.00e-35 144.00
IUUC-Ogl-077619 Oryza glaberrima 32.20 2.00e-36 148.00
IUUC-Ogu-078961 Oryza glumaepatula 31.79 4.00e-36 147.00
IUUC-Oin-079261 Oryza indica 31.16 6.00e-36 146.00
IUUC-Olo-080829 Oryza longistaminata 31.79 4.00e-36 147.00
IUUC-Ome-081599 Oryza meridionalis 31.58 1.00e-35 145.00
IUUC-Oni-082029 Oryza nivara 31.16 2.00e-35 144.00
IUUC-Opu-083657 Oryza punctata 32.41 3.00e-35 144.00
IUUC-Oru-084765 Oryza rufipogon 31.16 5.00e-36 146.00
IUUC-Osa-086136 Oryza sativa 31.16 2.00e-35 144.00
IUUC-Ola-087419 Oryzias latipes 58.61 0.00e+00 1466.00
IUUC-Oga-088885 Otolemur garnettii 80.87 0.00e+00 2110.00
IUUC-Oar-090361 Ovis aries 82.42 0.00e+00 2170.00
IUUC-Ptr-091424 Pan troglodytes 83.60 0.00e+00 2245.00
IUUC-Pan-092557 Papio anubis 83.25 0.00e+00 2201.00
IUUC-Psi-093980 Pelodiscus sinensis 69.02 0.00e+00 1804.00
IUUC-Pno-094989 Phaeosphaeria nodorum 28.92 4.00e-34 140.00
IUUC-Ppa-095929 Physcomitrella patens 34.37 4.00e-37 150.00
IUUC-Pfo-096296 Poecilia formosa 55.81 0.00e+00 1396.00
IUUC-Pab-097552 Pongo abelii 83.60 0.00e+00 2242.00
IUUC-Pop-099124 Populus trichocarpa 30.86 8.00e-34 139.00
IUUC-Pca-100417 Procavia capensis 74.43 0.00e+00 816.00
IUUC-Ppe-101574 Prunus persica 36.03 1.00e-32 135.00
IUUC-Pva-102906 Pteropus vampyrus 79.32 0.00e+00 2070.00
IUUC-Pgr-103405 Puccinia graminis 27.64 2.00e-30 129.00
IUUC-Ptt-103743 Puccinia triticina 28.08 4.00e-30 127.00
IUUC-Pte-104407 Pyrenophora teres 28.36 5.00e-33 137.00
IUUC-Pyt-104646 Pyrenophora triticirepentis 28.36 7.00e-33 137.00
IUUC-Sha-106797 Sarcophilus harrisii 71.31 0.00e+00 1843.00
IUUC-Sja-107740 Schizosaccharomyces japonicus 32.86 2.00e-34 141.00
IUUC-Spo-108090 Schizosaccharomyces pombe 31.66 5.00e-34 140.00
IUUC-Ssl-108513 Sclerotinia sclerotiorum 24.31 9.00e-23 103.00
IUUC-Sit-110676 Setaria italica 32.36 1.00e-35 145.00
IUUC-Sar-113437 Sorex araneus 73.51 0.00e+00 1878.00
IUUC-Sbi-114124 Sorghum bicolor 30.34 4.00e-31 130.00
IUUC-Sre-114999 Sporisorium reilianum 28.46 4.00e-29 124.00
IUUC-Ssc-116088 Sus scrofa 82.50 0.00e+00 2103.00
IUUC-Tgu-116854 Taeniopygia guttata 67.97 0.00e+00 1753.00
IUUC-Tru-117552 Takifugu rubripes 55.53 0.00e+00 1391.00
IUUC-Tsy-118821 Tarsius syrichta 79.05 0.00e+00 1320.00
IUUC-Tni-119891 Tetraodon nigroviridis 55.30 0.00e+00 1403.00
IUUC-Tca-121015 Theobroma cacao 31.45 5.00e-34 140.00
IUUC-Tre-122202 Trichoderma reesei 27.85 6.00e-27 117.00
IUUC-Tvi-122439 Trichoderma virens 28.54 6.00e-26 114.00
IUUC-Tae-123606 Triticum aestivum 36.53 6.00e-36 146.00
IUUC-Tur-126077 Triticum urartu 35.42 2.00e-34 142.00
IUUC-Tme-127029 Tuber melanosporum 29.05 3.00e-27 118.00
IUUC-Tbe-127811 Tupaia belangeri 69.62 0.00e+00 1085.00
IUUC-Ttr-128664 Tursiops truncatus 80.08 0.00e+00 1452.00
IUUC-Uma-129427 Ustilago maydis 27.92 7.00e-28 120.00
IUUC-Vda-129791 Verticillium dahliae 27.10 2.00e-17 85.90
IUUC-Vpa-130558 Vicugna pacos 76.00 0.00e+00 1945.00
IUUC-Vvi-131602 Vitis vinifera 33.64 6.00e-32 133.00
IUUC-Xtr-131965 Xenopus tropicalis 60.07 0.00e+00 1480.00
IUUC-Xma-133569 Xiphophorus maculatus 55.86 0.00e+00 1386.00
IUUC-Yli-134409 Yarrowia lipolytica 31.27 1.00e-22 102.00
IUUC-Zma-135450 Zea mays 32.80 4.00e-35 144.00
Created Date 25-Jun-2017

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