iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-060029

Ensembl Protein ID

ENSMGAP00000003512.2

UniProt Accession

G1MXE9; G1MXE9_MELGA

Protein Name

Uncharacterized protein

Gene Name

ARHGEF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000003749.2	ENSMGAT00000004216.2	ENSMGAP00000003512.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.10e-15	55.2	165	219

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deL+ +kGd+++v     +++gW++g  +l+gk G fP+n+v++++
   Q: 165  VVKARFNFKQTNEDELSVNKGDIIYVT--RVEEGGWWEG--TLNGKTGWFPSNYVREIK 219
           68999*********************7..999*******..8**************997 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MNPEEQVVTW LISLGVLNSP KKIIDDPEEF LKTSLKDGTV LCKLIHRLLP GSAEKYCLEP 60
KNEADCIGNI QEFLRGCAAL KVELFEPHDL YSGEQFSKVL STLTAVNKAT EDQPSEGPCS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCAATGAAT CCAGAAGAGC AAGTGGTAAC GTGGCTCATT TCGTTAGGAG TTCTGAACTC 60
CCCTAAGAAA ATAATTGATG ATCCAGAGGA GTTCCTGAAA ACTTCTCTGA AGGATGGAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

KEGG

mgp:100547020

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001631	Ailuropoda melanoleuca	66.20	0.00e+00	1050.00
IUUC-Apl-003960	Anas platyrhynchos	96.25	0.00e+00	1451.00
IUUC-Aca-004988	Anolis carolinensis	79.67	0.00e+00	1193.00
IUUC-Aly-005591	Arabidopsis lyrata	40.32	2.00e-09	56.60
IUUC-Ame-011546	Astyanax mexicanus	67.48	0.00e+00	977.00
IUUC-Bta-013527	Bos taurus	75.26	0.00e+00	1132.00
IUUC-Bdi-014394	Brachypodium distachyon	43.48	5.00e-08	51.60
IUUC-Cja-018935	Callithrix jacchus	75.26	0.00e+00	1134.00
IUUC-Cfa-021269	Canis familiaris	75.00	0.00e+00	1133.00
IUUC-Cpo-021620	Cavia porcellus	71.32	0.00e+00	1076.00
IUUC-Csa-023415	Chlorocebus sabaeus	75.13	0.00e+00	1135.00
IUUC-Dre-028580	Danio rerio	66.97	0.00e+00	1008.00
IUUC-Dno-029201	Dasypus novemcinctus	70.93	0.00e+00	1105.00
IUUC-Dor-030868	Dipodomys ordii	61.73	0.00e+00	845.00
IUUC-Eca-033500	Equus caballus	75.52	0.00e+00	1126.00
IUUC-Eeu-035269	Erinaceus europaeus	67.62	1.00e-135	476.00
IUUC-Fca-035683	Felis catus	74.23	0.00e+00	1106.00
IUUC-Fal-037611	Ficedula albicollis	92.11	0.00e+00	1400.00
IUUC-Gmo-038980	Gadus morhua	64.79	0.00e+00	935.00
IUUC-Gga-040940	Gallus gallus	97.80	0.00e+00	1492.00
IUUC-Gac-042203	Gasterosteus aculeatus	64.06	0.00e+00	973.00
IUUC-Ggo-044755	Gorilla gorilla	75.13	0.00e+00	1132.00
IUUC-Hsa-046210	Homo sapiens	74.87	0.00e+00	1129.00
IUUC-Hvu-047839	Hordeum vulgare	36.05	3.00e-08	50.80
IUUC-Lch-049517	Latimeria chalumnae	74.60	0.00e+00	1107.00
IUUC-Loc-052393	Lepisosteus oculatus	67.43	0.00e+00	1041.00
IUUC-Laf-054196	Loxodonta africana	74.84	0.00e+00	1101.00
IUUC-Mcc-055716	Macaca mulatta	75.00	0.00e+00	1133.00
IUUC-Meu-056285	Macropus eugenii	68.32	0.00e+00	636.00
IUUC-Mtr-058576	Medicago truncatula	46.15	1.00e-11	63.50
IUUC-Mmr-060803	Microcebus murinus	75.26	0.00e+00	1125.00
IUUC-Mdo-062654	Monodelphis domestica	77.25	0.00e+00	1157.00
IUUC-Mmu-063479	Mus musculus	73.58	0.00e+00	1092.00
IUUC-Mpu-066065	Mustela putorius furo	74.74	0.00e+00	1103.00
IUUC-Mlu-068222	Myotis lucifugus	73.75	0.00e+00	1091.00
IUUC-Nle-069379	Nomascus leucogenys	75.13	0.00e+00	1133.00
IUUC-Opr-070687	Ochotona princeps	57.64	0.00e+00	649.00
IUUC-Ont-072240	Oreochromis niloticus	60.78	0.00e+00	938.00
IUUC-Oan-073067	Ornithorhynchus anatinus	81.57	0.00e+00	1239.00
IUUC-Ocu-074852	Oryctolagus cuniculus	74.10	0.00e+00	1107.00
IUUC-Oba-075543	Oryza barthii	34.29	1.50e+00	27.30
IUUC-Ogu-078135	Oryza glumaepatula	34.29	1.50e+00	27.30
IUUC-Ome-081704	Oryza meridionalis	34.29	2.20e+00	26.90
IUUC-Oni-082520	Oryza nivara	34.29	5.40e-01	28.10
IUUC-Opu-083443	Oryza punctata	34.29	1.00e+00	27.70
IUUC-Oga-089048	Otolemur garnettii	69.50	0.00e+00	959.00
IUUC-Oar-089339	Ovis aries	75.26	0.00e+00	1132.00
IUUC-Pan-092666	Papio anubis	73.26	0.00e+00	1087.00
IUUC-Psi-093116	Pelodiscus sinensis	86.53	0.00e+00	1337.00
IUUC-Pma-094701	Petromyzon marinus	57.14	4.00e-118	417.00
IUUC-Pfo-097394	Poecilia formosa	64.87	0.00e+00	976.00
IUUC-Pab-098567	Pongo abelii	75.13	0.00e+00	1133.00
IUUC-Pca-100997	Procavia capensis	65.55	0.00e+00	907.00
IUUC-Pva-102500	Pteropus vampyrus	73.97	0.00e+00	1079.00
IUUC-Ptt-103822	Puccinia triticina	22.48	2.00e-08	54.30
IUUC-Rno-104974	Rattus norvegicus	73.91	0.00e+00	1071.00
IUUC-Sar-113420	Sorex araneus	73.32	0.00e+00	1070.00
IUUC-Ssc-115679	Sus scrofa	75.58	0.00e+00	996.00
IUUC-Tgu-117069	Taeniopygia guttata	91.48	0.00e+00	1402.00
IUUC-Tru-118488	Takifugu rubripes	59.66	0.00e+00	850.00
IUUC-Tsy-119243	Tarsius syrichta	68.01	0.00e+00	769.00
IUUC-Tni-120584	Tetraodon nigroviridis	62.76	0.00e+00	936.00
IUUC-Tbe-127994	Tupaia belangeri	61.60	0.00e+00	901.00
IUUC-Ttr-128839	Tursiops truncatus	73.84	0.00e+00	1089.00
IUUC-Vpa-130144	Vicugna pacos	69.63	0.00e+00	989.00
IUUC-Xtr-132624	Xenopus tropicalis	71.88	0.00e+00	1110.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence