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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063756
Ensembl Protein ID ENSMUSP00000095200.2
UniProt Accession Q6ZQ82; E9QLL3; RHG26_MOUSE
Genbank Protein ID BAC97986.1; ENSMUSP00000095200
Protein Name Rho GTPase-activating protein 26; Rho-type GTPase-activating protein 26
Genbank Nucleotide ID AK129176; AC110730
Gene Name Arhgap26; Kiaa0621
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000036452.17 ENSMUST00000148850.7 ENSMUSP00000121894.1
ENSMUSG00000036452.17 ENSMUST00000097593.8 ENSMUSP00000095200.2
ENSMUSG00000036452.17 ENSMUST00000155576.7 ENSMUSP00000122371.1
ENSMUSG00000036452.17 ENSMUST00000154551.7 ENSMUSP00000123145.1
ENSMUSG00000036452.17 ENSMUST00000137497.7 ENSMUSP00000121197.1
ENSMUSG00000036452.17 ENSMUST00000141058.7 ENSMUSP00000119865.1
ENSMUSG00000036452.17 ENSMUST00000151757.7 ENSMUSP00000122448.1
ENSMUSG00000036452.17 ENSMUST00000187912.1 ENSMUSP00000141188.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitecircBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IIDiRefIndexHINTMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
PHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 2.90e-12 47.5 760 812
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           k ++ly  +a++d eL++++G v + + + +q+ gWl+g  +l+gk Gl+Pen+ve
   Q: 760  KAKALYACQAEHDSELSFTAGTVFDNV-HPSQEPGWLEG--TLNGKTGLIPENYVE 812
           679************************.***********..8*************8 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     GTPase-activating protein for RHOA and CDC42.
 GTPase-activating protein for RHOA and CDC42.
Protein Sequence
(Fasta)
MGLPALEFSD CCLDSPHFRE TLKSHEAELD KTNKFIKELI KDGKSLISAL KNLSSAKRKF 60
ADSLNEFKFQ CIGDAETDDE MCIARSLQEF AAVLRNLEDE RSRMIENASE VLITPLEKFR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063756|UBD,SH3|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTGCTCCTCC TGGGGCCGTC GTTCTTTTAC AAAGAGGGGT GGAGGTTGTT GTTCCTTTTT 60
TTTTTTTTTT TTCCTTTTTC TTTGTAATGA ATGGAGGGCG GCGGCGACTG CAGCAGCTGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063756|UBD,SH3|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0965--Cell junction
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0343--GTPase activation
KW-1185--Reference proteome
KW-0728--SH3 domain
Interpro

IPR027267--AH/BAR-dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR030061--RHG26
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain
PROSITE

PS50003--PH_DOMAIN
PS50238--RHOGAP
PS50002--SH3
Pfam

PF00169--PH
PF00620--RhoGAP
PF14604--SH3_9
SMART

SM00233--PH
SM00324--RhoGAP
SM00326--SH3
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005856--C:cytoskeleton
GO:0005925--C:focal adhesion
GO:0005096--F:GTPase activator activity
GO:0005543--F:phospholipid binding
GO:0030036--P:actin cytoskeleton organization
GO:0051056--P:regulation of small GTPase mediated signal transduction
GO:0007165--P:signal transduction
KEGG mmu:71302
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001613 Ailuropoda melanoleuca 96.20 0.00e+00 1361.00
IUUC-Apl-003321 Anas platyrhynchos 83.38 0.00e+00 1101.00
IUUC-Aca-004570 Anolis carolinensis 88.60 0.00e+00 1148.00
IUUC-Ame-011422 Astyanax mexicanus 78.21 0.00e+00 845.00
IUUC-Bta-013262 Bos taurus 96.85 0.00e+00 1086.00
IUUC-Cel-018542 Caenorhabditis elegans 43.14 6.00e-131 461.00
IUUC-Cja-019208 Callithrix jacchus 98.05 0.00e+00 1191.00
IUUC-Cfa-020928 Canis familiaris 97.10 0.00e+00 1191.00
IUUC-Cpo-021338 Cavia porcellus 96.68 0.00e+00 1419.00
IUUC-Csa-023570 Chlorocebus sabaeus 97.73 0.00e+00 1189.00
IUUC-Dno-029143 Dasypus novemcinctus 95.95 0.00e+00 1401.00
IUUC-Dor-030697 Dipodomys ordii 97.05 0.00e+00 1404.00
IUUC-Dme-032147 Drosophila melanogaster 44.43 1.00e-140 494.00
IUUC-Ete-032645 Echinops telfairi 87.78 0.00e+00 1031.00
IUUC-Eca-033791 Equus caballus 96.68 0.00e+00 1409.00
IUUC-Eeu-035202 Erinaceus europaeus 82.14 2.00e-175 609.00
IUUC-Fca-036131 Felis catus 96.25 0.00e+00 1374.00
IUUC-Fal-037129 Ficedula albicollis 91.95 0.00e+00 1113.00
IUUC-Gga-041023 Gallus gallus 90.26 0.00e+00 1144.00
IUUC-Ggo-044863 Gorilla gorilla 97.06 0.00e+00 1406.00
IUUC-Hsa-046471 Homo sapiens 96.93 0.00e+00 1400.00
IUUC-Itr-049060 Ictidomys tridecemlineatus 96.81 0.00e+00 1438.00
IUUC-Lch-050300 Latimeria chalumnae 74.71 0.00e+00 1023.00
IUUC-Loc-052782 Lepisosteus oculatus 80.12 0.00e+00 1039.00
IUUC-Laf-053585 Loxodonta africana 95.21 0.00e+00 1369.00
IUUC-Mcc-055458 Macaca mulatta 97.89 0.00e+00 1193.00
IUUC-Meu-056107 Macropus eugenii 77.15 0.00e+00 1077.00
IUUC-Mga-059914 Meleagris gallopavo 87.56 0.00e+00 1016.00
IUUC-Mmr-060728 Microcebus murinus 96.59 0.00e+00 1300.00
IUUC-Mdo-062387 Monodelphis domestica 88.11 0.00e+00 1310.00
IUUC-Nle-069043 Nomascus leucogenys 92.50 0.00e+00 874.00
IUUC-Opr-071168 Ochotona princeps 84.64 0.00e+00 1201.00
IUUC-Ont-072338 Oreochromis niloticus 76.74 0.00e+00 891.00
IUUC-Oan-073441 Ornithorhynchus anatinus 90.43 0.00e+00 943.00
IUUC-Ocu-073915 Oryctolagus cuniculus 95.45 0.00e+00 1382.00
IUUC-Ola-086319 Oryzias latipes 76.28 0.00e+00 933.00
IUUC-Oar-089349 Ovis aries 96.95 0.00e+00 1186.00
IUUC-Ptr-091027 Pan troglodytes 97.05 0.00e+00 1405.00
IUUC-Pan-092791 Papio anubis 97.89 0.00e+00 1191.00
IUUC-Psi-093144 Pelodiscus sinensis 90.41 0.00e+00 1179.00
IUUC-Pab-097783 Pongo abelii 96.93 0.00e+00 1407.00
IUUC-Pva-102980 Pteropus vampyrus 94.36 0.00e+00 1426.00
IUUC-Rno-105142 Rattus norvegicus 98.93 0.00e+00 1254.00
IUUC-Sha-107213 Sarcophilus harrisii 90.51 0.00e+00 1088.00
IUUC-Tru-117767 Takifugu rubripes 73.78 0.00e+00 965.00
IUUC-Tsy-119150 Tarsius syrichta 93.49 0.00e+00 1357.00
IUUC-Tni-119893 Tetraodon nigroviridis 76.21 0.00e+00 681.00
IUUC-Ttr-129028 Tursiops truncatus 85.60 0.00e+00 1100.00
Created Date 25-Jun-2017

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