iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093523

Ensembl Protein ID

ENSPSIP00000010124.1

UniProt Accession

K7FQ14; K7FQ14_PELSI

Genbank Protein ID

ENSPSIP00000010124

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01089793

Gene Name

TRIM59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000009192.1	ENSPSIT00000010175.1	ENSPSIP00000010124.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.50e-08	33.9	10	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefr..........CPlCr 46
           C+iC++ f+d p+vlpC H+f+++Cl+ +     + s +f+          CP Cr
   Q: 10   CSICYSIFED-PRVLPCSHTFCRNCLESV----LQLSSNFSiwrplrlplkCPNCR 60
           **********.**************9888....333333333556666666***98 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MHHFEEELTC SICYSIFEDP RVLPCSHTFC RNCLESVLQL SSNFSIWRPL RLPLKCPNCR 60
SIVEIPPSGT ESLPINFALK AIIEKYQQED HPDVATCSEH YRQPLNVYCL LDRKLVCGHC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGTTTCGA GGCTAGCTGC AGGCTGAGAA AGCGAACCTT ACCTCACCTC GGGAGGGAGT 60
CAGTGGCTGC CTGAGGGGAA ACCTGTGCGA GCCGGGTGAG TTTCCTTGCT ACGGCGGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046597--P:negative regulation of viral entry into host cell

KEGG

pss:102455731

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002249	Ailuropoda melanoleuca	61.82	6.00e-147	513.00
IUUC-Apl-003996	Anas platyrhynchos	71.11	1.00e-156	545.00
IUUC-Aca-005141	Anolis carolinensis	69.78	5.00e-164	570.00
IUUC-Ame-011353	Astyanax mexicanus	53.87	2.00e-106	379.00
IUUC-Bta-013440	Bos taurus	64.21	7.00e-140	489.00
IUUC-Cfa-021168	Canis familiaris	62.22	2.00e-149	521.00
IUUC-Cpo-021702	Cavia porcellus	57.99	1.00e-133	469.00
IUUC-Csa-024141	Chlorocebus sabaeus	63.30	9.00e-138	483.00
IUUC-Dre-028408	Danio rerio	47.56	6.00e-86	310.00
IUUC-Dno-029180	Dasypus novemcinctus	62.32	4.00e-147	513.00
IUUC-Eca-034357	Equus caballus	62.50	5.00e-148	516.00
IUUC-Fca-036287	Felis catus	62.56	7.00e-150	523.00
IUUC-Gga-040739	Gallus gallus	73.04	4.00e-176	610.00
IUUC-Ggo-045307	Gorilla gorilla	62.07	2.00e-144	504.00
IUUC-Hsa-045690	Homo sapiens	62.56	4.00e-145	507.00
IUUC-Itr-048230	Ictidomys tridecemlineatus	61.18	1.00e-148	519.00
IUUC-Laf-054522	Loxodonta africana	61.82	4.00e-145	507.00
IUUC-Mcc-055145	Macaca mulatta	63.55	9.00e-147	512.00
IUUC-Meu-056214	Macropus eugenii	45.58	2.00e-48	185.00
IUUC-Mmr-061197	Microcebus murinus	62.56	2.00e-150	525.00
IUUC-Mmu-064217	Mus musculus	60.10	7.00e-142	496.00
IUUC-Mpu-065691	Mustela putorius furo	62.32	4.00e-150	523.00
IUUC-Mlu-067742	Myotis lucifugus	61.23	3.00e-138	484.00
IUUC-Nle-069722	Nomascus leucogenys	62.56	4.00e-151	527.00
IUUC-Oan-073382	Ornithorhynchus anatinus	59.85	3.00e-135	474.00
IUUC-Oar-089206	Ovis aries	62.07	9.00e-149	519.00
IUUC-Pan-092189	Papio anubis	63.79	2.00e-147	514.00
IUUC-Pma-094162	Petromyzon marinus	37.68	2.00e-50	192.00
IUUC-Pfo-096032	Poecilia formosa	51.47	1.00e-95	342.00
IUUC-Pva-103089	Pteropus vampyrus	61.48	1.00e-139	488.00
IUUC-Rno-105440	Rattus norvegicus	59.85	7.00e-142	496.00
IUUC-Ssc-115809	Sus scrofa	61.33	4.00e-139	487.00
IUUC-Tru-118402	Takifugu rubripes	48.80	2.00e-96	345.00
IUUC-Tni-119737	Tetraodon nigroviridis	46.75	2.00e-90	325.00
IUUC-Ttr-128921	Tursiops truncatus	61.73	4.00e-141	494.00
IUUC-Vpa-130397	Vicugna pacos	62.81	3.00e-147	514.00
IUUC-Xtr-132752	Xenopus tropicalis	55.52	1.00e-90	326.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence