iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132877

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01089428

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000029963.1	ENSXETT00000066297.1	ENSXETP00000060168.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.90e-95	320.2	757	920

Active Site

Position(s)	Description	Evidence
889	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 175  klvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerka 263
           +l++e+r+ +g++eq++af +Gfn v+pl++l++F+e+ele+++cG++e+d++d++++t y++ yt++s++i+wFw++++e+++e r +
   Q: 757  SLMAEWRFSRGVEEQTKAFLDGFNAVVPLQWLQYFDEKELEVMLCGMQEVDLSDWQRNTVYRH-YTRNSKQIIWFWQFVKEMDNEVRLR 844
           59***********************************************************99.************************* PP
   S: 264  fLqFvTgssrlPlgGfaelk....prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           +LqFvTg++rlPlgGfael+    p++f+i+k +++++lP+s+TCfn+L+LP+Y+s+e+lkekLl+Aieet+gF++
   Q: 845  LLQFVTGTCRLPLGGFAELMgsngPQKFCIEKVGKETWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQ 920
           **************************************************************************96 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MATASPRPGN RNSLEDLQLH VTVSCAKLKR KKNWFGTTVY TELAVDGETK KTAKSSSSSN 60
PKWEERLTVS VTPQTTLEFK VWSHHSWKAD ALLGKTAVDL KQALETHNRK LERVKEQLKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCACAG CCTCGCCACG GCCGGGGAAT CGAAACAGTC TTGAAGATTT ACAGCTGCAC 60
GTGACAGGTA ATTTGTATGT GTGCTCGGAT GTAAAGCTTG ATCTCCCCTC CAGTATTTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001213	Ailuropoda melanoleuca	69.80	0.00e+00	1215.00
IUUC-Apl-003310	Anas platyrhynchos	71.57	0.00e+00	1254.00
IUUC-Aca-005388	Anolis carolinensis	69.50	0.00e+00	1202.00
IUUC-Bta-012857	Bos taurus	69.29	0.00e+00	1203.00
IUUC-Cja-019448	Callithrix jacchus	69.81	0.00e+00	1229.00
IUUC-Cfa-020728	Canis familiaris	69.82	0.00e+00	1202.00
IUUC-Cpo-021635	Cavia porcellus	66.95	0.00e+00	1206.00
IUUC-Csa-023805	Chlorocebus sabaeus	78.82	0.00e+00	964.00
IUUC-Dre-028245	Danio rerio	65.51	0.00e+00	1062.00
IUUC-Dno-029618	Dasypus novemcinctus	70.08	0.00e+00	1221.00
IUUC-Ete-032779	Echinops telfairi	78.26	0.00e+00	895.00
IUUC-Eca-033313	Equus caballus	70.48	0.00e+00	1205.00
IUUC-Eeu-035259	Erinaceus europaeus	62.79	0.00e+00	1049.00
IUUC-Fca-035420	Felis catus	69.34	0.00e+00	1206.00
IUUC-Fal-037335	Ficedula albicollis	71.37	0.00e+00	1256.00
IUUC-Gga-040246	Gallus gallus	69.70	0.00e+00	1238.00
IUUC-Gac-042211	Gasterosteus aculeatus	79.37	0.00e+00	996.00
IUUC-Ggo-045001	Gorilla gorilla	67.90	0.00e+00	1066.00
IUUC-Hsa-046544	Homo sapiens	69.41	0.00e+00	1222.00
IUUC-Itr-048860	Ictidomys tridecemlineatus	69.33	0.00e+00	1193.00
IUUC-Lch-050398	Latimeria chalumnae	80.46	0.00e+00	993.00
IUUC-Loc-052116	Lepisosteus oculatus	68.30	0.00e+00	1181.00
IUUC-Laf-053551	Loxodonta africana	69.53	0.00e+00	1219.00
IUUC-Mga-059986	Meleagris gallopavo	71.05	0.00e+00	1255.00
IUUC-Mmr-060945	Microcebus murinus	70.30	0.00e+00	1231.00
IUUC-Mdo-063024	Monodelphis domestica	67.24	0.00e+00	1145.00
IUUC-Mmu-063202	Mus musculus	69.08	0.00e+00	1173.00
IUUC-Mpu-065773	Mustela putorius furo	69.94	0.00e+00	1200.00
IUUC-Nle-069188	Nomascus leucogenys	69.83	0.00e+00	1227.00
IUUC-Opr-070965	Ochotona princeps	68.94	0.00e+00	1182.00
IUUC-Ont-072226	Oreochromis niloticus	79.90	0.00e+00	1004.00
IUUC-Oan-073497	Ornithorhynchus anatinus	71.41	0.00e+00	1223.00
IUUC-Ocu-073891	Oryctolagus cuniculus	65.71	0.00e+00	1118.00
IUUC-Ola-087438	Oryzias latipes	77.63	0.00e+00	995.00
IUUC-Oga-087922	Otolemur garnettii	69.66	0.00e+00	1217.00
IUUC-Oar-089317	Ovis aries	69.58	0.00e+00	1186.00
IUUC-Ptr-090484	Pan troglodytes	69.41	0.00e+00	1221.00
IUUC-Pan-092117	Papio anubis	69.83	0.00e+00	1227.00
IUUC-Psi-093338	Pelodiscus sinensis	71.97	0.00e+00	1262.00
IUUC-Pfo-096171	Poecilia formosa	79.12	0.00e+00	1004.00
IUUC-Pab-098654	Pongo abelii	76.20	0.00e+00	924.00
IUUC-Pva-102811	Pteropus vampyrus	62.70	0.00e+00	1052.00
IUUC-Rno-106125	Rattus norvegicus	69.05	0.00e+00	1201.00
IUUC-Sha-107243	Sarcophilus harrisii	69.83	0.00e+00	1214.00
IUUC-Ssc-115368	Sus scrofa	69.73	0.00e+00	1200.00
IUUC-Tgu-117079	Taeniopygia guttata	71.67	0.00e+00	1250.00
IUUC-Tru-118062	Takifugu rubripes	64.20	0.00e+00	1165.00
IUUC-Tsy-119507	Tarsius syrichta	65.32	0.00e+00	1114.00
IUUC-Tni-120151	Tetraodon nigroviridis	65.69	0.00e+00	1142.00
IUUC-Ttr-129260	Tursiops truncatus	60.04	0.00e+00	962.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence