iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001347

Ensembl Protein ID

ENSAMEP00000008067.1

UniProt Accession

G1LM80; G1LM80_AILME

Genbank Protein ID

ENSAMEP00000008067

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01003579

Gene Name

HIC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000007657.1	ENSAMET00000008402.1	ENSAMEP00000008067.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	9.90e-13	48.4	166	225

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgkl 65
           +Dvi+vv++  f+ahk vLaasS ++++l  +        +  +++ d v+p vfr +l+F+Ytg+l
   Q: 166  CDVIIVVQNALFRAHKNVLAASSAYLKSLVVH-------DNLLNLDhDmVSPAVFRLVLDFIYTGRL 225
           9*****************************77.......4566677678****************98 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

KTPEFVGFEV PGPGSSRGHI WDGEPVNRPL SRVQLCFCEP PTQPRCAGGR SRLCGAKSCR 60
AARWRHSCSS ACRPGPLQIR VCGKRGGAET RPGRGEDGPA GQTDRGPGGG RSHVPPWIRR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAACCCCAG AGTTTGTGGG ATTCGAAGTT CCGGGGCCTG GGTCCTCACG TGGGCACATC 60
TGGGATGGTG AACCTGTCAA TAGACCCCTC TCCCGCGTCC AGCTCTGCTT CTGTGAGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR028424--HIC1
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0046872--F:metal ion binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030178--P:negative regulation of Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004217	Anas platyrhynchos	67.20	1.00e-69	257.00
IUUC-Aca-004680	Anolis carolinensis	75.52	2.00e-67	250.00
IUUC-Ame-010967	Astyanax mexicanus	64.12	2.00e-91	330.00
IUUC-Bta-013567	Bos taurus	92.63	4.00e-145	508.00
IUUC-Cja-019621	Callithrix jacchus	92.65	1.00e-60	224.00
IUUC-Cfa-020731	Canis familiaris	94.81	3.00e-161	561.00
IUUC-Cpo-021326	Cavia porcellus	89.56	8.00e-152	531.00
IUUC-Csa-023645	Chlorocebus sabaeus	92.36	1.00e-147	516.00
IUUC-Dre-028027	Danio rerio	60.90	1.00e-87	317.00
IUUC-Dno-028900	Dasypus novemcinctus	91.48	6.00e-147	514.00
IUUC-Dor-030484	Dipodomys ordii	75.90	3.00e-34	139.00
IUUC-Ete-033019	Echinops telfairi	75.90	2.00e-34	140.00
IUUC-Eca-033737	Equus caballus	68.82	4.00e-68	252.00
IUUC-Eeu-035190	Erinaceus europaeus	77.11	2.00e-35	142.00
IUUC-Fca-036031	Felis catus	68.82	4.00e-68	252.00
IUUC-Fal-036980	Ficedula albicollis	63.14	1.00e-109	390.00
IUUC-Gmo-039209	Gadus morhua	68.98	3.00e-67	249.00
IUUC-Gga-040708	Gallus gallus	60.73	8.00e-106	377.00
IUUC-Gac-041742	Gasterosteus aculeatus	76.96	1.00e-76	281.00
IUUC-Ggo-044591	Gorilla gorilla	98.22	7.00e-136	477.00
IUUC-Hsa-046769	Homo sapiens	92.61	6.00e-145	508.00
IUUC-Itr-048627	Ictidomys tridecemlineatus	92.21	2.00e-152	533.00
IUUC-Lch-049412	Latimeria chalumnae	57.79	2.00e-102	366.00
IUUC-Loc-051883	Lepisosteus oculatus	64.24	5.00e-90	325.00
IUUC-Laf-053358	Loxodonta africana	92.14	5.00e-149	521.00
IUUC-Mcc-054981	Macaca mulatta	92.36	1.00e-147	516.00
IUUC-Meu-056181	Macropus eugenii	93.62	2.00e-42	166.00
IUUC-Mga-059592	Meleagris gallopavo	72.79	4.00e-102	365.00
IUUC-Mmr-061560	Microcebus murinus	90.64	3.00e-146	512.00
IUUC-Mdo-062511	Monodelphis domestica	79.55	8.00e-87	314.00
IUUC-Mmu-064258	Mus musculus	91.15	2.00e-148	519.00
IUUC-Mpu-065911	Mustela putorius furo	94.81	5.00e-161	561.00
IUUC-Mlu-067575	Myotis lucifugus	72.97	4.00e-103	368.00
IUUC-Nle-069726	Nomascus leucogenys	86.24	6.00e-59	221.00
IUUC-Opr-071056	Ochotona princeps	77.11	6.00e-35	142.00
IUUC-Ont-072493	Oreochromis niloticus	65.40	5.00e-78	285.00
IUUC-Ocu-073887	Oryctolagus cuniculus	69.23	3.00e-67	249.00
IUUC-Ola-086584	Oryzias latipes	61.34	2.00e-86	313.00
IUUC-Oga-088774	Otolemur garnettii	92.86	1.00e-152	533.00
IUUC-Ptr-090491	Pan troglodytes	96.81	9.00e-121	426.00
IUUC-Pan-092901	Papio anubis	68.82	4.00e-68	252.00
IUUC-Psi-093290	Pelodiscus sinensis	63.55	1.00e-69	257.00
IUUC-Pma-094179	Petromyzon marinus	70.51	4.00e-31	125.00
IUUC-Pfo-096282	Poecilia formosa	58.48	3.00e-85	309.00
IUUC-Pab-098488	Pongo abelii	92.36	5.00e-145	508.00
IUUC-Pca-100667	Procavia capensis	93.48	1.00e-137	483.00
IUUC-Pva-102421	Pteropus vampyrus	91.15	8.00e-153	534.00
IUUC-Rno-105528	Rattus norvegicus	91.15	7.00e-142	497.00
IUUC-Sar-113478	Sorex araneus	97.08	8.00e-115	407.00
IUUC-Ssc-115420	Sus scrofa	87.47	3.00e-153	535.00
IUUC-Tgu-116642	Taeniopygia guttata	62.65	2.00e-107	383.00
IUUC-Tru-118583	Takifugu rubripes	64.69	2.00e-81	296.00
IUUC-Tni-119907	Tetraodon nigroviridis	61.83	1.00e-57	216.00
IUUC-Xtr-132210	Xenopus tropicalis	61.88	2.00e-109	390.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence