iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
circBase	miRTarBase	microRNA	TRANSFAC
RepTar	RAID2
Protein-protein Interaction
IID	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	mUbiSiDa
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	7.60e-21	75.4	37	103

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           Dv++vv++++f+ah+++Laa++++F+al++++++es+++ ++ ++d  +e+f  ll+++Ytg+++++
   Q: 37   DVTFVVEKKHFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLRYIYTGRATLT 103
           9**************************************************************9875 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MSNSHPLRPF TAVGEIDHVH ILSEHIGALL IGEEYGDVTF VVEKKHFPAH RVILAARCQY 60
FRALLYGGMR ESQPEAEIPL QDTTAEAFTM LLRYIYTGRA TLTDEKEEVL LDFLSLAHKY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAGCGGGC GCGCGCCGCG ACGGCGGCGG CGAGGAAGGC GGCGACGGCG GCGGTCGAGG 60
GGGCGGTGGC CACGAGGCGG GGTCGCTGCT GGCGGAAGAG ACGTGTGTGG CGGCTTCTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR034091--BTBD9_BACK-like_dom
IPR000421--FA58C
IPR008979--Galactose-bd-like
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF00754--F5_F8_type_C

SMART

SM00875--BACK
SM00225--BTB

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0008344--P:adult locomotory behavior
GO:0048512--P:circadian behavior
GO:0042748--P:circadian sleep/wake cycle, non-REM sleep
GO:0007616--P:long-term memory
GO:0050804--P:modulation of synaptic transmission
GO:0060586--P:multicellular organismal iron ion homeostasis
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030162--P:regulation of proteolysis
GO:1900242--P:regulation of synaptic vesicle endocytosis
GO:0050951--P:sensory perception of temperature stimulus
GO:0042428--P:serotonin metabolic process

KEGG

mmu:224671

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001333	Ailuropoda melanoleuca	97.66	0.00e+00	787.00
IUUC-Apl-003275	Anas platyrhynchos	90.51	0.00e+00	1127.00
IUUC-Aca-004407	Anolis carolinensis	91.17	0.00e+00	1124.00
IUUC-Ame-011645	Astyanax mexicanus	76.92	0.00e+00	884.00
IUUC-Bta-012635	Bos taurus	97.66	0.00e+00	786.00
IUUC-Bci-013715	Botrytis cinerea	25.60	3.00e-06	45.80
IUUC-Cel-018453	Caenorhabditis elegans	40.39	2.00e-115	409.00
IUUC-Cja-019564	Callithrix jacchus	97.42	0.00e+00	790.00
IUUC-Cfa-020412	Canis familiaris	98.18	0.00e+00	790.00
IUUC-Cpo-022116	Cavia porcellus	96.93	0.00e+00	1160.00
IUUC-Cre-022671	Chlamydomonas reinhardtii	41.00	5.00e-04	39.70
IUUC-Csa-023458	Chlorocebus sabaeus	97.66	0.00e+00	789.00
IUUC-Cho-024472	Choloepus hoffmanni	87.09	0.00e+00	657.00
IUUC-Cin-025433	Ciona intestinalis	56.35	0.00e+00	657.00
IUUC-Csv-025875	Ciona savignyi	54.95	3.00e-178	618.00
IUUC-Dre-028362	Danio rerio	72.73	0.00e+00	890.00
IUUC-Dno-029542	Dasypus novemcinctus	97.42	0.00e+00	790.00
IUUC-Dor-030108	Dipodomys ordii	93.11	4.00e-164	571.00
IUUC-Dme-031643	Drosophila melanogaster	53.97	9.00e-171	593.00
IUUC-Ete-033062	Echinops telfairi	97.42	5.00e-157	547.00
IUUC-Eca-034168	Equus caballus	96.61	0.00e+00	1174.00
IUUC-Eeu-035231	Erinaceus europaeus	97.81	4.00e-105	375.00
IUUC-Fca-035540	Felis catus	63.47	0.00e+00	635.00
IUUC-Fal-037629	Ficedula albicollis	91.05	0.00e+00	1120.00
IUUC-Gmo-038968	Gadus morhua	74.28	3.00e-149	521.00
IUUC-Gga-040297	Gallus gallus	90.34	0.00e+00	1127.00
IUUC-Gac-042219	Gasterosteus aculeatus	74.86	6.00e-143	500.00
IUUC-Ggo-045584	Gorilla gorilla	95.90	0.00e+00	1157.00
IUUC-Hsa-046262	Homo sapiens	96.59	0.00e+00	1167.00
IUUC-Itr-047909	Ictidomys tridecemlineatus	97.66	0.00e+00	784.00
IUUC-Lch-050280	Latimeria chalumnae	87.65	0.00e+00	938.00
IUUC-Loc-052601	Lepisosteus oculatus	78.69	0.00e+00	965.00
IUUC-Laf-053474	Loxodonta africana	96.40	0.00e+00	783.00
IUUC-Mcc-055501	Macaca mulatta	96.25	0.00e+00	1166.00
IUUC-Meu-056851	Macropus eugenii	86.09	3.00e-173	600.00
IUUC-Mga-059540	Meleagris gallopavo	93.63	0.00e+00	954.00
IUUC-Mmr-061009	Microcebus murinus	95.90	0.00e+00	1186.00
IUUC-Mdo-061824	Monodelphis domestica	93.18	0.00e+00	1103.00
IUUC-Mpu-065943	Mustela putorius furo	98.18	0.00e+00	790.00
IUUC-Mlu-067349	Myotis lucifugus	97.42	0.00e+00	788.00
IUUC-Nle-069794	Nomascus leucogenys	95.73	0.00e+00	1157.00
IUUC-Opr-070569	Ochotona princeps	95.61	0.00e+00	894.00
IUUC-Ont-071668	Oreochromis niloticus	77.31	0.00e+00	937.00
IUUC-Oan-072886	Ornithorhynchus anatinus	94.23	0.00e+00	967.00
IUUC-Ocu-074010	Oryctolagus cuniculus	97.92	0.00e+00	788.00
IUUC-Ola-086345	Oryzias latipes	68.89	6.00e-68	249.00
IUUC-Oga-088389	Otolemur garnettii	96.27	0.00e+00	1172.00
IUUC-Oar-089674	Ovis aries	97.92	0.00e+00	788.00
IUUC-Ptr-091004	Pan troglodytes	95.90	0.00e+00	1157.00
IUUC-Pan-092824	Papio anubis	92.83	0.00e+00	1118.00
IUUC-Psi-093770	Pelodiscus sinensis	90.85	0.00e+00	1132.00
IUUC-Pma-094226	Petromyzon marinus	68.94	0.00e+00	779.00
IUUC-Pfo-096112	Poecilia formosa	76.33	0.00e+00	946.00
IUUC-Pab-098462	Pongo abelii	91.87	0.00e+00	1147.00
IUUC-Pca-100966	Procavia capensis	73.08	0.00e+00	741.00
IUUC-Pva-102618	Pteropus vampyrus	96.61	0.00e+00	1172.00
IUUC-Pte-104324	Pyrenophora teres	34.57	2.00e-06	47.40
IUUC-Rno-105840	Rattus norvegicus	98.80	0.00e+00	1211.00
IUUC-Sha-106785	Sarcophilus harrisii	93.07	0.00e+00	1082.00
IUUC-Sar-113661	Sorex araneus	97.52	0.00e+00	985.00
IUUC-Ssc-115629	Sus scrofa	89.91	5.00e-110	389.00
IUUC-Tgu-117110	Taeniopygia guttata	90.71	0.00e+00	1118.00
IUUC-Tru-117672	Takifugu rubripes	75.04	0.00e+00	920.00
IUUC-Tsy-119176	Tarsius syrichta	96.10	0.00e+00	1171.00
IUUC-Tni-120213	Tetraodon nigroviridis	77.50	0.00e+00	915.00
IUUC-Tbe-128031	Tupaia belangeri	91.68	0.00e+00	1104.00
IUUC-Ttr-129304	Tursiops truncatus	75.65	0.00e+00	872.00
IUUC-Vpa-130638	Vicugna pacos	83.66	0.00e+00	1021.00
IUUC-Xtr-132304	Xenopus tropicalis	86.56	0.00e+00	1031.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence