iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-089083

Ensembl Protein ID

ENSOGAP00000022484.1

UniProt Accession

H0Y291; H0Y291_OTOGA

Genbank Protein ID

ENSOGAP00000022484

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03110125

Gene Name

RNF149

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000034221.1	ENSOGAT00000032552.1	ENSOGAP00000022484.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.40e-06	28.7	266	307

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C e+f  kd  ++lpC+H+fh+ C+  w         + +CP C+
   Q: 266  CAVCIESFkvKDIIRILPCKHIFHRICIDPW------LLDHRTCPMCK 307
           ********8866699****************......9999******6 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAWRRQPEAG VGARGVLALL ALALCASEAW GRALEWYSAV VGTEYVAPKT NLTVWSVSES 60
GRFGDSSPKE GVQGLVGVPR APDGDPEGCA PDTSFQVPGC RGSAPWVALV ARGGCTFKDK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTGGC GGCGGCAGCC TGAGGCCGGT GTCGGGGCCC GCGGCGTGCT GGCGCTGCTG 60
GCCTTGGCCC TGTGCGCGTC CGAGGCCTGG GGCCGGGCGC TCGAGTGGTA CTCGGCGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0035690--P:cellular response to drug
GO:0043409--P:negative regulation of MAPK cascade
GO:0031647--P:regulation of protein stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001968	Ailuropoda melanoleuca	83.74	9.00e-175	605.00
IUUC-Apl-004109	Anas platyrhynchos	70.79	4.00e-102	363.00
IUUC-Bta-012340	Bos taurus	80.06	2.00e-168	585.00
IUUC-Cja-019566	Callithrix jacchus	83.97	5.00e-172	596.00
IUUC-Cfa-020289	Canis familiaris	82.43	4.00e-110	390.00
IUUC-Cpo-021916	Cavia porcellus	66.79	6.00e-73	266.00
IUUC-Csa-024084	Chlorocebus sabaeus	87.67	1.00e-176	612.00
IUUC-Cho-024305	Choloepus hoffmanni	78.06	9.00e-129	452.00
IUUC-Dno-030098	Dasypus novemcinctus	79.20	1.00e-177	615.00
IUUC-Dor-030620	Dipodomys ordii	73.63	2.00e-140	491.00
IUUC-Ete-032306	Echinops telfairi	79.48	3.00e-168	584.00
IUUC-Fca-035950	Felis catus	82.11	5.00e-121	426.00
IUUC-Fal-037429	Ficedula albicollis	66.40	2.00e-134	471.00
IUUC-Fso-038141	Fusarium solani	40.00	9.00e-14	71.60
IUUC-Gga-041201	Gallus gallus	65.71	1.00e-133	469.00
IUUC-Ggo-045429	Gorilla gorilla	85.56	2.00e-169	588.00
IUUC-Hsa-046191	Homo sapiens	84.04	4.00e-175	607.00
IUUC-Itr-048018	Ictidomys tridecemlineatus	78.65	6.00e-153	533.00
IUUC-Lch-049498	Latimeria chalumnae	60.76	6.00e-129	454.00
IUUC-Laf-054239	Loxodonta africana	70.50	1.00e-134	472.00
IUUC-Meu-056382	Macropus eugenii	72.96	1.00e-147	516.00
IUUC-Mga-059435	Meleagris gallopavo	68.25	3.00e-67	247.00
IUUC-Mvi-060468	Microbotryum violaceum	39.81	7.00e-13	69.30
IUUC-Mmr-061513	Microcebus murinus	91.69	0.00e+00	676.00
IUUC-Mdo-063028	Monodelphis domestica	73.64	1.00e-153	536.00
IUUC-Mmu-063545	Mus musculus	76.78	5.00e-153	533.00
IUUC-Mpu-066370	Mustela putorius furo	82.46	3.00e-168	584.00
IUUC-Mlu-067271	Myotis lucifugus	72.30	4.00e-136	477.00
IUUC-Nle-069207	Nomascus leucogenys	86.18	9.00e-175	605.00
IUUC-Opr-070704	Ochotona princeps	70.04	1.00e-93	335.00
IUUC-Oan-072837	Ornithorhynchus anatinus	67.83	5.00e-138	483.00
IUUC-Ocu-074671	Oryctolagus cuniculus	77.27	4.00e-121	427.00
IUUC-Oar-089254	Ovis aries	79.18	5.00e-112	396.00
IUUC-Ptr-090940	Pan troglodytes	85.91	2.00e-174	604.00
IUUC-Pan-092636	Papio anubis	87.40	3.00e-177	614.00
IUUC-Psi-093435	Pelodiscus sinensis	72.38	4.00e-95	340.00
IUUC-Pab-098525	Pongo abelii	86.80	1.00e-169	588.00
IUUC-Pva-102395	Pteropus vampyrus	79.70	1.00e-174	605.00
IUUC-Pgr-103263	Puccinia graminis	42.47	2.00e-10	61.20
IUUC-Rno-105789	Rattus norvegicus	78.24	2.00e-153	535.00
IUUC-Sha-107305	Sarcophilus harrisii	71.19	3.00e-93	333.00
IUUC-Ssc-115598	Sus scrofa	81.20	3.00e-166	577.00
IUUC-Tgu-116463	Taeniopygia guttata	66.30	1.00e-128	452.00
IUUC-Tsy-118915	Tarsius syrichta	85.37	2.00e-109	388.00
IUUC-Tme-126970	Tuber melanosporum	49.06	2.00e-12	67.00
IUUC-Tbe-127906	Tupaia belangeri	64.08	2.00e-82	298.00
IUUC-Xtr-131821	Xenopus tropicalis	65.08	1.00e-128	452.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence