iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000012104.2	ENSPPYT00000033024.1	ENSPPYP00000023760.1
ENSPPYG00000012104.2	ENSPPYT00000014044.1	ENSPPYP00000013495.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.40e-06	28.1	269	310

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C e f  kd  ++lpC+H+fh+ C+  w         + +CP C+
   Q: 269  CAVCIENFkvKDIIRILPCKHIFHRICIDPW------LLDHRTCPMCK 310
           ********8866699****************......9999******6 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MAWRRREAGV GAHGVLALAL LALALCVPGA RGRALEWFSA VVNIEYVDPQ TNLTVWSVSE 60
SGRFGDSSPK EGAHGLVGVP WAPGGDLEGC APDTRFFVPE PGGRGAAPWV ALVARGGCTF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGAGACCCCG GGGCGGATCG CGGTCCGAGG CTCCGCGGAG CTTACGCCTG CGCACAGCGC 60
GGCCGGGCGG GCGGGGGCGG AGCCAGGGCC GATCACGCCC TTCGTCCGCT CCGCCAGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0035690--P:cellular response to drug
GO:0043409--P:negative regulation of MAPK cascade
GO:0031647--P:regulation of protein stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000870	Aegilops tauschii	37.97	7.00e-12	63.50
IUUC-Aml-001968	Ailuropoda melanoleuca	84.12	2.00e-173	601.00
IUUC-Apl-004109	Anas platyrhynchos	71.26	1.00e-100	358.00
IUUC-Bta-012340	Bos taurus	82.39	5.00e-167	580.00
IUUC-Cja-019566	Callithrix jacchus	91.21	0.00e+00	653.00
IUUC-Cfa-020289	Canis familiaris	84.51	1.00e-107	381.00
IUUC-Cpo-021916	Cavia porcellus	66.67	1.00e-72	266.00
IUUC-Csa-024084	Chlorocebus sabaeus	95.87	0.00e+00	653.00
IUUC-Cho-024305	Choloepus hoffmanni	83.45	1.00e-132	465.00
IUUC-Cne-026985	Cryptococcus neoformans	29.91	7.00e-11	63.20
IUUC-Cme-027122	Cyanidioschyzon merolae	37.97	7.00e-12	65.90
IUUC-Dno-030098	Dasypus novemcinctus	82.69	2.00e-180	625.00
IUUC-Dor-030620	Dipodomys ordii	74.42	4.00e-143	500.00
IUUC-Ete-032306	Echinops telfairi	82.91	2.00e-173	601.00
IUUC-Fca-035950	Felis catus	83.69	5.00e-116	409.00
IUUC-Fal-037429	Ficedula albicollis	67.49	2.00e-135	475.00
IUUC-Fso-038141	Fusarium solani	41.25	2.00e-15	77.00
IUUC-Gga-041201	Gallus gallus	65.96	6.00e-131	460.00
IUUC-Ggo-045429	Gorilla gorilla	97.74	0.00e+00	660.00
IUUC-Hsa-046191	Homo sapiens	98.45	0.00e+00	701.00
IUUC-Itr-048018	Ictidomys tridecemlineatus	80.83	4.00e-153	534.00
IUUC-Lch-049498	Latimeria chalumnae	62.85	8.00e-131	459.00
IUUC-Laf-054239	Loxodonta africana	68.91	1.00e-134	472.00
IUUC-Meu-056382	Macropus eugenii	73.89	3.00e-154	538.00
IUUC-Mmr-061513	Microcebus murinus	86.65	4.00e-172	597.00
IUUC-Mdo-063028	Monodelphis domestica	74.72	5.00e-157	546.00
IUUC-Mmu-063545	Mus musculus	77.84	2.00e-149	521.00
IUUC-Mpu-066370	Mustela putorius furo	84.31	3.00e-165	574.00
IUUC-Mlu-067271	Myotis lucifugus	76.90	1.00e-135	475.00
IUUC-Nle-069207	Nomascus leucogenys	97.93	0.00e+00	685.00
IUUC-Opr-070704	Ochotona princeps	71.79	2.00e-91	328.00
IUUC-Oan-072837	Ornithorhynchus anatinus	71.51	2.00e-143	501.00
IUUC-Ocu-074671	Oryctolagus cuniculus	80.95	1.00e-116	412.00
IUUC-Oga-089083	Otolemur garnettii	83.72	7.00e-175	606.00
IUUC-Oar-089254	Ovis aries	82.48	1.00e-110	391.00
IUUC-Ptr-090940	Pan troglodytes	98.60	0.00e+00	676.00
IUUC-Pan-092636	Papio anubis	96.31	0.00e+00	654.00
IUUC-Psi-093435	Pelodiscus sinensis	73.82	2.00e-94	338.00
IUUC-Pva-102395	Pteropus vampyrus	80.68	7.00e-168	583.00
IUUC-Pgr-103263	Puccinia graminis	43.84	2.00e-11	64.30
IUUC-Rno-105789	Rattus norvegicus	78.06	3.00e-146	511.00
IUUC-Sha-107305	Sarcophilus harrisii	73.89	3.00e-94	337.00
IUUC-Ssc-115598	Sus scrofa	83.70	1.00e-163	568.00
IUUC-Tgu-116463	Taeniopygia guttata	68.08	9.00e-132	462.00
IUUC-Tsy-118915	Tarsius syrichta	88.84	1.00e-106	379.00
IUUC-Tme-126970	Tuber melanosporum	49.06	2.00e-12	67.40
IUUC-Tbe-127906	Tupaia belangeri	64.66	5.00e-78	283.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence