iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052766

Ensembl Protein ID

ENSLOCP00000008456.1

UniProt Accession

W5MJ97; W5MJ97_LEPOC

Genbank Protein ID

ENSLOCP00000008456

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AHAT01036725

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000006985.1	ENSLOCT00000008466.1	ENSLOCP00000008456.1
ENSLOCG00000006985.1	ENSLOCT00000008490.1	ENSLOCP00000008480.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.60e-15	56.5	856	896

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC +gg+    l++Ce C  +fHp+Cl++     +p+ + w+C++C+
   Q: 856  WCFVCSKGGS----LLCCESCPAAFHPDCLNIG----MPDGS-WYCNDCK 896
           8*********....*******************....9***8.******8 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MDLNAKGSSL PLMPEHLSPV SMKQAPEALS SRKSQAAGVE MSADPAILMD KAAAAQLVAT 60
LQDTVIQISG ERLKDLTSRV LNGDQDKLPK LCAAEPPPLL KGGDPPTPHA SPPKKGDSPE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACATTCA AATTCATTCG ACTCGAGTGA GTCATCTAAT CCCAGCAGCC GAAATGTACG 60
TTGGTATCAT GCGGTCATCA GCCTGTGGCG GTGCGTGTTC ACTCCAGTGC AATCGTTTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0051216--P:cartilage development
GO:0048706--P:embryonic skeletal system development
GO:0010452--P:histone H3-K36 methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002181	Ailuropoda melanoleuca	52.88	0.00e+00	1321.00
IUUC-Apl-003677	Anas platyrhynchos	54.33	0.00e+00	1389.00
IUUC-Aca-004278	Anolis carolinensis	67.40	0.00e+00	1172.00
IUUC-Ame-011932	Astyanax mexicanus	74.02	0.00e+00	1141.00
IUUC-Bta-012522	Bos taurus	55.00	0.00e+00	1321.00
IUUC-Cja-018908	Callithrix jacchus	52.76	0.00e+00	1312.00
IUUC-Cfa-020894	Canis familiaris	52.91	0.00e+00	1334.00
IUUC-Cpo-021982	Cavia porcellus	58.30	0.00e+00	1284.00
IUUC-Csa-023807	Chlorocebus sabaeus	67.69	0.00e+00	1112.00
IUUC-Cho-024405	Choloepus hoffmanni	77.42	9.00e-76	278.00
IUUC-Csv-026298	Ciona savignyi	41.28	1.00e-61	230.00
IUUC-Dre-027492	Danio rerio	77.41	0.00e+00	1202.00
IUUC-Dno-030020	Dasypus novemcinctus	52.19	0.00e+00	1131.00
IUUC-Dor-031103	Dipodomys ordii	64.29	0.00e+00	974.00
IUUC-Dme-032193	Drosophila melanogaster	39.85	5.00e-118	419.00
IUUC-Ete-032488	Echinops telfairi	63.61	0.00e+00	986.00
IUUC-Eca-034066	Equus caballus	53.30	0.00e+00	1334.00
IUUC-Eeu-035199	Erinaceus europaeus	48.02	1.00e-124	441.00
IUUC-Fca-035434	Felis catus	55.03	0.00e+00	1195.00
IUUC-Fal-037113	Ficedula albicollis	54.00	0.00e+00	1406.00
IUUC-Gmo-039686	Gadus morhua	73.10	0.00e+00	1092.00
IUUC-Gga-040273	Gallus gallus	53.95	0.00e+00	1400.00
IUUC-Gac-042123	Gasterosteus aculeatus	72.79	0.00e+00	1164.00
IUUC-Ggo-044643	Gorilla gorilla	52.62	0.00e+00	1334.00
IUUC-Hsa-046380	Homo sapiens	52.62	0.00e+00	1321.00
IUUC-Itr-048658	Ictidomys tridecemlineatus	70.04	0.00e+00	1081.00
IUUC-Lch-050217	Latimeria chalumnae	70.80	0.00e+00	1167.00
IUUC-Laf-053780	Loxodonta africana	53.65	0.00e+00	1347.00
IUUC-Mcc-054928	Macaca mulatta	67.82	0.00e+00	1126.00
IUUC-Mga-059576	Meleagris gallopavo	70.07	0.00e+00	1155.00
IUUC-Mmr-061045	Microcebus murinus	58.04	0.00e+00	1289.00
IUUC-Mdo-062576	Monodelphis domestica	68.23	0.00e+00	1157.00
IUUC-Mmu-063640	Mus musculus	53.19	0.00e+00	1318.00
IUUC-Mac-065303	Musa acuminata	29.22	6.00e-11	62.80
IUUC-Mpu-066512	Mustela putorius furo	52.77	0.00e+00	1314.00
IUUC-Mlu-067261	Myotis lucifugus	66.62	0.00e+00	997.00
IUUC-Nle-069896	Nomascus leucogenys	52.28	0.00e+00	1259.00
IUUC-Opr-070842	Ochotona princeps	61.76	0.00e+00	901.00
IUUC-Ont-072197	Oreochromis niloticus	79.59	0.00e+00	1142.00
IUUC-Oan-073496	Ornithorhynchus anatinus	56.29	0.00e+00	991.00
IUUC-Ocu-074758	Oryctolagus cuniculus	52.55	0.00e+00	1286.00
IUUC-Olo-080702	Oryza longistaminata	41.47	2.00e-45	177.00
IUUC-Opu-083371	Oryza punctata	42.19	5.00e-47	182.00
IUUC-Ola-087518	Oryzias latipes	63.11	0.00e+00	832.00
IUUC-Oga-088702	Otolemur garnettii	51.31	0.00e+00	1126.00
IUUC-Oar-090265	Ovis aries	61.76	0.00e+00	996.00
IUUC-Ptr-091055	Pan troglodytes	52.62	0.00e+00	1322.00
IUUC-Pan-092752	Papio anubis	74.56	0.00e+00	1084.00
IUUC-Psi-093620	Pelodiscus sinensis	54.88	0.00e+00	1415.00
IUUC-Pfo-097464	Poecilia formosa	71.11	0.00e+00	1153.00
IUUC-Pab-098051	Pongo abelii	52.77	0.00e+00	1336.00
IUUC-Pop-099927	Populus trichocarpa	29.95	1.00e-11	65.10
IUUC-Pva-102473	Pteropus vampyrus	70.27	0.00e+00	982.00
IUUC-Rno-105056	Rattus norvegicus	69.30	0.00e+00	1134.00
IUUC-Sha-107494	Sarcophilus harrisii	54.45	0.00e+00	1363.00
IUUC-Sar-113310	Sorex araneus	57.50	0.00e+00	1151.00
IUUC-Ssc-116344	Sus scrofa	71.17	0.00e+00	1101.00
IUUC-Tgu-116786	Taeniopygia guttata	54.11	0.00e+00	1385.00
IUUC-Tru-117638	Takifugu rubripes	68.34	0.00e+00	1151.00
IUUC-Tsy-118937	Tarsius syrichta	68.19	0.00e+00	1111.00
IUUC-Tni-120452	Tetraodon nigroviridis	66.90	0.00e+00	1138.00
IUUC-Tca-121456	Theobroma cacao	32.52	1.00e-19	92.00
IUUC-Tbe-127291	Tupaia belangeri	71.14	0.00e+00	1036.00
IUUC-Xtr-132673	Xenopus tropicalis	55.87	0.00e+00	1244.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence