iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052823

Ensembl Protein ID

ENSLOCP00000018185.1

UniProt Accession

W5NC26; W5NC26_LEPOC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000014764.1	ENSLOCT00000018217.1	ENSLOCP00000018185.1
ENSLOCG00000014764.1	ENSLOCT00000018219.1	ENSLOCP00000018187.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.30e-17	61.7	594	629
UBD/Beta-Prp	2.20e-41	142.2	379	629

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gHtd+ ++la  +  + ++++++D+ i +WD  t+ 
   Q: 594  GHTDELWGLAVhPWkPNFLTCGHDKHISLWDSVTHQ 629
           8*******988866678**************87765 PP

UBD/Beta-Prp

   S: 53   aevtavkfspdgk....ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee....tl 133
            + +++ fs++        v  s+D+++ vw+ +  + +  +k  ++ v + +f+p++  ++++   + +  w le g+ +++     +
   Q: 379  RALACIAFSKSNGgstlCVVDDSNDHVLSVWEWQREERLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGGSLIKKqglfEK 467
           457888888776677767788899********************************9999999999********************999 PP
   S: 134  sghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq............ 210
           +++ ++v cv+++++g+  ++G   + + +W   t+++ +  +g+h++ +  l + +ng+ +  g++d++++ wd              
   Q: 468  QEKPKFVLCVTFSENGDT-ITGDSSGNILVWGKGTNRITYAIQGAHEGGIFALCMLRNGTLVSGGGKDRKLISWDGNyqkiqaveipep 555
           9999**********7765.79******************************************************99666666666666 PP
   S: 211  ..........tgec...................vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgd 255
                     +g+c                   + + +ghtd  + ++++p +  ++++++D+ i++Wd+ + +
   Q: 556  ygpvrtvaegKGDCvligttrnyvlqgtlfgdfIPITQGHTDELWGLAVHPWKPNFLTCGHDKHISLWDSVTHQ 629
           66666666555555999999999**********************************************98876 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MQTSVAVENG VAATSASPLG MTMKPIPEEA VPCDHLACPE AFSIVDDSAS AASSMEVTDR 60
IASLEQRVQM QEDEIQLLKS ALADVVRRLN ISEEQQAMLN RKGPTKDQTA VKKSTPTESA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAATTTGAA ACTGACTGCC TAATCAAAGC TTCAGATGGC TTACGGTCCC TAATCTTGTT 60
CTTAATGACA TCATCCAGAT TGTGTGCTTG GGAGCAAGAG GGTATTAGAA TAGGAGCGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036368--P:cone photoresponse recovery

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002077	Ailuropoda melanoleuca	78.19	0.00e+00	1320.00
IUUC-Apl-004179	Anas platyrhynchos	83.01	0.00e+00	1357.00
IUUC-Aca-004993	Anolis carolinensis	76.90	0.00e+00	1263.00
IUUC-Ame-011332	Astyanax mexicanus	79.76	0.00e+00	1356.00
IUUC-Bta-013419	Bos taurus	68.25	0.00e+00	1084.00
IUUC-Cel-018623	Caenorhabditis elegans	29.88	3.00e-86	313.00
IUUC-Cja-018976	Callithrix jacchus	79.95	0.00e+00	1344.00
IUUC-Cfa-021276	Canis familiaris	81.28	0.00e+00	1327.00
IUUC-Csa-023355	Chlorocebus sabaeus	79.86	0.00e+00	1326.00
IUUC-Cin-025784	Ciona intestinalis	55.85	0.00e+00	753.00
IUUC-Csv-026305	Ciona savignyi	48.53	0.00e+00	764.00
IUUC-Dre-028728	Danio rerio	82.87	0.00e+00	1387.00
IUUC-Dno-029055	Dasypus novemcinctus	79.17	0.00e+00	1348.00
IUUC-Dor-030628	Dipodomys ordii	79.24	0.00e+00	1307.00
IUUC-Dme-032093	Drosophila melanogaster	38.46	1.00e-121	431.00
IUUC-Eca-034266	Equus caballus	82.45	0.00e+00	1393.00
IUUC-Fca-035446	Felis catus	80.64	0.00e+00	1320.00
IUUC-Fal-036734	Ficedula albicollis	80.83	0.00e+00	1340.00
IUUC-Gmo-038689	Gadus morhua	75.32	0.00e+00	1304.00
IUUC-Gga-040934	Gallus gallus	85.64	0.00e+00	1058.00
IUUC-Gac-042476	Gasterosteus aculeatus	76.30	0.00e+00	1321.00
IUUC-Ggo-044828	Gorilla gorilla	80.57	0.00e+00	1376.00
IUUC-Hsa-045664	Homo sapiens	80.66	0.00e+00	1373.00
IUUC-Lch-050508	Latimeria chalumnae	85.92	0.00e+00	1446.00
IUUC-Laf-054164	Loxodonta africana	77.62	0.00e+00	1249.00
IUUC-Mcc-055810	Macaca mulatta	79.74	0.00e+00	1340.00
IUUC-Mga-059405	Meleagris gallopavo	82.05	0.00e+00	1349.00
IUUC-Mmr-061144	Microcebus murinus	83.13	0.00e+00	1372.00
IUUC-Mdo-062834	Monodelphis domestica	84.34	0.00e+00	1410.00
IUUC-Mmu-063955	Mus musculus	81.07	0.00e+00	1327.00
IUUC-Mpu-066240	Mustela putorius furo	79.90	0.00e+00	1303.00
IUUC-Mlu-067847	Myotis lucifugus	78.96	0.00e+00	971.00
IUUC-Nle-069783	Nomascus leucogenys	80.64	0.00e+00	1355.00
IUUC-Opr-070409	Ochotona princeps	74.16	0.00e+00	1216.00
IUUC-Ont-072468	Oreochromis niloticus	80.63	0.00e+00	1389.00
IUUC-Oan-073315	Ornithorhynchus anatinus	80.39	0.00e+00	1325.00
IUUC-Ocu-074604	Oryctolagus cuniculus	80.95	0.00e+00	1132.00
IUUC-Ola-086734	Oryzias latipes	76.18	0.00e+00	1303.00
IUUC-Oga-089105	Otolemur garnettii	79.72	0.00e+00	1325.00
IUUC-Oar-090057	Ovis aries	81.70	0.00e+00	1358.00
IUUC-Ptr-091138	Pan troglodytes	80.90	0.00e+00	1377.00
IUUC-Pan-092691	Papio anubis	73.93	0.00e+00	1217.00
IUUC-Psi-093076	Pelodiscus sinensis	80.64	0.00e+00	1343.00
IUUC-Pma-094555	Petromyzon marinus	58.28	0.00e+00	832.00
IUUC-Pfo-096794	Poecilia formosa	76.28	0.00e+00	1289.00
IUUC-Pab-097787	Pongo abelii	80.45	0.00e+00	1377.00
IUUC-Pva-102676	Pteropus vampyrus	79.12	0.00e+00	1303.00
IUUC-Rno-105971	Rattus norvegicus	73.06	0.00e+00	1143.00
IUUC-Sha-107530	Sarcophilus harrisii	82.35	0.00e+00	1342.00
IUUC-Ssc-116169	Sus scrofa	72.10	0.00e+00	930.00
IUUC-Tgu-117046	Taeniopygia guttata	82.60	0.00e+00	1333.00
IUUC-Tru-118596	Takifugu rubripes	76.63	0.00e+00	1330.00
IUUC-Tsy-119142	Tarsius syrichta	74.96	0.00e+00	969.00
IUUC-Tni-120377	Tetraodon nigroviridis	77.60	0.00e+00	1327.00
IUUC-Tbe-127916	Tupaia belangeri	68.65	0.00e+00	888.00
IUUC-Ttr-129042	Tursiops truncatus	80.66	0.00e+00	1366.00
IUUC-Xtr-132117	Xenopus tropicalis	79.53	0.00e+00	1303.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence