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Tag Content
iUUCD ID IUUC-Xtr-132869
Ensembl Protein ID ENSXETP00000022290.3
UniProt Accession F6Z1Z0; F6Z1Z0_XENTR
Genbank Protein ID ENSXETP00000022290
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID AAMC01017091
Gene Name kmt2a
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSXETG00000010087.3 ENSXETT00000022290.3 ENSXETP00000022290.3
ENSXETG00000010087.3 ENSXETT00000022279.3 ENSXETP00000022279.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 1.80e-22 79.5 1424 1478
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 1    ekvClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCrsk 54
           +k+C+vCg++++ +k+l+eC+kCr+ +Hp+Cl+++ ++++p+++k  wiC+kC ++
   Q: 1424 CKFCHVCGRQQQATKQLLECNKCRNSYHPECLGPN-YPTKPTKKKrvWICTKCVRC 1478
           589********************************.******9999*******876 PP
   
Organism Xenopus tropicalis
Protein Sequence
(Fasta)
MAHSCRWRFP ARPGTGRRLG ARHRLSAILI DDVSEYRSNP GASGSAGASS AGTLAPGGPG 60
NCLGVALGFD AALQVSAAIG NNLRRFRDVS GGSSGEEEQF LGFGSDEEVK GRSPAKSPKD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Xtr-132869|E3,PHD|Xenopus tropicalis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGCGCACA GCTGTCGGTG GCGGTTCCCT GCTCGGCCCG GGACTGGCCG GAGGCTGGGG 60
GCCCGGCACC GATTATCAGC TATACTGATA GACGATGTGA GCGAGTACAG AAGCAACCCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Xtr-132869|E3,PHD|Xenopus tropicalis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001487--Bromodomain
IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50014--BROMODOMAIN_2
PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2
Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC
SMART

SM00297--BROMO
SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0021782--P:glial cell development
GO:0048823--P:nucleate erythrocyte development
GO:0048339--P:paraxial mesoderm development
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001054 Aegilops tauschii 35.58 2.00e-14 74.30
IUUC-Aml-002274 Ailuropoda melanoleuca 59.85 0.00e+00 3565.00
IUUC-Atr-002455 Amborella trichopoda 48.10 1.00e-39 158.00
IUUC-Apl-003478 Anas platyrhynchos 71.64 0.00e+00 1523.00
IUUC-Aca-005086 Anolis carolinensis 71.84 0.00e+00 1250.00
IUUC-Aly-006448 Arabidopsis lyrata 40.17 2.00e-39 158.00
IUUC-Ame-011195 Astyanax mexicanus 43.12 0.00e+00 776.00
IUUC-Bta-012974 Bos taurus 62.35 0.00e+00 1393.00
IUUC-Bdi-014882 Brachypodium distachyon 32.16 5.00e-28 119.00
IUUC-Bra-017422 Brassica rapa 32.66 9.00e-28 118.00
IUUC-Cja-019226 Callithrix jacchus 65.77 0.00e+00 2144.00
IUUC-Cfa-021049 Canis familiaris 61.85 0.00e+00 1439.00
IUUC-Cpo-021459 Cavia porcellus 61.57 0.00e+00 1388.00
IUUC-Csa-023434 Chlorocebus sabaeus 61.49 0.00e+00 1410.00
IUUC-Cho-024652 Choloepus hoffmanni 56.68 0.00e+00 1283.00
IUUC-Cin-025724 Ciona intestinalis 53.68 1.00e-97 351.00
IUUC-Csv-026268 Ciona savignyi 33.71 1.00e-116 415.00
IUUC-Dre-028180 Danio rerio 60.53 0.00e+00 1012.00
IUUC-Dno-029068 Dasypus novemcinctus 60.41 0.00e+00 1385.00
IUUC-Dor-030550 Dipodomys ordii 69.28 0.00e+00 1021.00
IUUC-Dme-032023 Drosophila melanogaster 47.11 1.00e-91 332.00
IUUC-Ete-032834 Echinops telfairi 57.32 0.00e+00 1280.00
IUUC-Eca-033615 Equus caballus 62.46 0.00e+00 1382.00
IUUC-Eeu-035136 Erinaceus europaeus 63.03 0.00e+00 784.00
IUUC-Fca-036453 Felis catus 56.47 0.00e+00 1006.00
IUUC-Fal-037256 Ficedula albicollis 65.58 0.00e+00 2145.00
IUUC-Gmo-038641 Gadus morhua 61.43 0.00e+00 969.00
IUUC-Gga-040828 Gallus gallus 64.88 0.00e+00 2083.00
IUUC-Gac-041452 Gasterosteus aculeatus 64.12 0.00e+00 1043.00
IUUC-Gma-043554 Glycine max 48.37 2.00e-37 150.00
IUUC-Ggo-045124 Gorilla gorilla 56.59 0.00e+00 1404.00
IUUC-Hsa-046143 Homo sapiens 56.74 0.00e+00 1377.00
IUUC-Hvu-047762 Hordeum vulgare 34.81 5.00e-21 95.90
IUUC-Itr-049024 Ictidomys tridecemlineatus 59.37 0.00e+00 2057.00
IUUC-Lch-049704 Latimeria chalumnae 65.38 0.00e+00 1558.00
IUUC-Lpe-051476 Leersia perrieri 30.09 9.00e-25 108.00
IUUC-Loc-052181 Lepisosteus oculatus 71.08 0.00e+00 1171.00
IUUC-Laf-053946 Loxodonta africana 59.35 0.00e+00 3407.00
IUUC-Mcc-055508 Macaca mulatta 60.43 0.00e+00 1395.00
IUUC-Meu-056485 Macropus eugenii 61.29 0.00e+00 1442.00
IUUC-Mtr-058327 Medicago truncatula 40.51 3.00e-38 154.00
IUUC-Mga-059943 Meleagris gallopavo 65.40 0.00e+00 1987.00
IUUC-Mmr-061178 Microcebus murinus 61.78 0.00e+00 1412.00
IUUC-Mdo-063031 Monodelphis domestica 62.29 0.00e+00 1452.00
IUUC-Mmu-063650 Mus musculus 60.31 0.00e+00 1360.00
IUUC-Mac-064935 Musa acuminata 33.50 2.00e-30 127.00
IUUC-Mpu-066495 Mustela putorius furo 60.91 0.00e+00 1637.00
IUUC-Mlu-068045 Myotis lucifugus 60.03 0.00e+00 1357.00
IUUC-Nle-069064 Nomascus leucogenys 65.86 0.00e+00 2123.00
IUUC-Opr-071043 Ochotona princeps 70.44 0.00e+00 1108.00
IUUC-Ont-072556 Oreochromis niloticus 62.98 0.00e+00 1006.00
IUUC-Oan-073324 Ornithorhynchus anatinus 59.98 0.00e+00 1660.00
IUUC-Ocu-074190 Oryctolagus cuniculus 60.11 0.00e+00 2633.00
IUUC-Obr-076458 Oryza brachyantha 32.66 2.00e-28 120.00
IUUC-Ogl-077851 Oryza glaberrima 32.14 1.00e-27 118.00
IUUC-Ogu-078706 Oryza glumaepatula 31.84 2.00e-28 120.00
IUUC-Oin-079802 Oryza indica 29.13 7.00e-23 102.00
IUUC-Olo-080577 Oryza longistaminata 48.37 6.00e-36 145.00
IUUC-Osa-085421 Oryza sativa 32.14 2.00e-27 117.00
IUUC-Ola-087176 Oryzias latipes 59.47 0.00e+00 1013.00
IUUC-Oga-088208 Otolemur garnettii 61.32 0.00e+00 1404.00
IUUC-Oar-090152 Ovis aries 62.10 0.00e+00 1417.00
IUUC-Ptr-091127 Pan troglodytes 56.67 0.00e+00 1373.00
IUUC-Pan-092679 Papio anubis 61.27 0.00e+00 1398.00
IUUC-Psi-094059 Pelodiscus sinensis 56.40 0.00e+00 1474.00
IUUC-Pma-094258 Petromyzon marinus 53.21 3.00e-175 608.00
IUUC-Ppa-095221 Physcomitrella patens 33.82 2.00e-31 130.00
IUUC-Pfo-096536 Poecilia formosa 64.35 0.00e+00 1026.00
IUUC-Pab-098262 Pongo abelii 56.51 0.00e+00 1412.00
IUUC-Pop-099585 Populus trichocarpa 32.16 2.00e-28 121.00
IUUC-Pca-100358 Procavia capensis 61.55 0.00e+00 1356.00
IUUC-Ppe-101920 Prunus persica 33.71 2.00e-28 120.00
IUUC-Pva-102522 Pteropus vampyrus 63.40 0.00e+00 1469.00
IUUC-Pte-104182 Pyrenophora teres 33.90 6.00e-05 42.40
IUUC-Rno-105200 Rattus norvegicus 60.85 0.00e+00 1332.00
IUUC-Sha-107174 Sarcophilus harrisii 60.72 0.00e+00 2710.00
IUUC-Smo-109164 Selaginella moellendorffii 49.35 1.00e-39 158.00
IUUC-Sit-110552 Setaria italica 31.90 5.00e-29 122.00
IUUC-Sly-111176 Solanum lycopersicum 47.71 3.00e-35 143.00
IUUC-Sar-113503 Sorex araneus 59.29 0.00e+00 1232.00
IUUC-Tgu-117047 Taeniopygia guttata 64.84 0.00e+00 2119.00
IUUC-Tru-118328 Takifugu rubripes 56.31 0.00e+00 1030.00
IUUC-Tsy-118953 Tarsius syrichta 57.95 0.00e+00 1226.00
IUUC-Tni-120837 Tetraodon nigroviridis 58.63 0.00e+00 1022.00
IUUC-Tca-121624 Theobroma cacao 32.14 3.00e-29 124.00
IUUC-Tae-124647 Triticum aestivum 28.30 2.00e-21 96.70
IUUC-Tbe-127950 Tupaia belangeri 53.17 0.00e+00 1495.00
IUUC-Ttr-128643 Tursiops truncatus 63.32 0.00e+00 1993.00
IUUC-Vpa-130660 Vicugna pacos 75.22 0.00e+00 988.00
IUUC-Vvi-131476 Vitis vinifera 46.15 6.00e-40 159.00
IUUC-Xma-133393 Xiphophorus maculatus 62.62 0.00e+00 981.00
Created Date 25-Jun-2017

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