iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Stu-112820

Ensembl Protein ID

PGSC0003DMT400080363

UniProt Accession

M1D3E1; M1D3E1_SOLTU

Protein Name

Ubiquitinyl hydrolase 1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PGSC0003DMG400031289	PGSC0003DMT400080363	PGSC0003DMT400080363

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.90e-79	266.3	231	801

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgye 88
           Gl+NlgNtC++NS++Q L++++ lr ++le    ++        +g+l+ +++klf+e    + +++a++p++++ +l+++a++f+gy+
   Q: 231  GLHNLGNTCFFNSIIQNLLAVNRLRGYFLE--LDEC--------DGPLAAAFKKLFTETSigDASRSAINPKSFFGSLCAKAPQFRGYQ 309
           9*****************************..4444........589***********999999************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           q+D++E+l++lld+l +e                 +++++ ++++++ k+++ ++ +F+g+l+s+++clec+++s  +epfldlslpvp
   Q: 310  QHDSHELLHCLLDGLGTEE---------------LTARKKLKSSQDHGKSPTYVDAIFGGRLSSTVTCLECGHSSLVYEPFLDLSLPVP 383
           ***************9988...............234455567789999**************************************** PP
   S: 178  gkeetkke................................................................................. 185
            k++ +k+                                                                                 
   Q: 384  TKKTPSKKaqlvsrvkkakhapkrsgrvrlkinrdaasfnsqsaqesgsksfcqvqssapiaegtevpsdcalvdsldassmaddmglt 472
           ***99988********************************************************************************* PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 473  shniysslkskneknvdnvtgqptsednfswldyldqdvlpngneqnddcvtgqstsmdnftcseyldqdimpkgddvasqadilsnqg 561
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 562  caaenivqpnvslqndlnapsdskltfgeeacspddlmrlddqgqskspdcniasqfgeevevkdwnarevehnsasssrflsvdsnld 650
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 651  ssarleeveaplqvkdseilllpykeetsttndvlkgesevspdaagceqdlldfdgfgglfnepepvagpaekpllsgaasmangfge 739
           ***************************************************************************************** PP
   S: 186  .......................slqdcLesftkeeelegenk.yycekckkkqeaekklklk 224
                                  s+++cL+ ftk+e l + +  ++ce+c k+ + e++++lk
   Q: 740  assaignssesdpdevdstdapvSVESCLACFTKPELLSKTEHaWQCENCAKLLR-EQRMRLK 801
           **************************************876544*******9885.6666665 PP

Organism

Solanum tuberosum

Protein Sequence
(Fasta)

MVKKAKRKAR GGAKERQNHV ASPNPIAQQD TQNVNAPEDG VTAVNEKKTC PHIDKGIDVE 60
KVSAKLGSSG PVRCEDCREG ADNRRAAKGK GKHGKKKGGG ESKSASKAIW VCLECGHFSC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTGTAGCT GTTTTTTTCT ATATGATATA CTAAATCTAT ACTCTTTTTA TGTGACCGCT 60
AATCTGTTGA AATTACTGGA AAAAATCTTT GCTTTTTTCA TCCATAGTTT CAGGTAAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

sot:102604177

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001931	Ailuropoda melanoleuca	29.19	4.00e-36	145.00
IUUC-Atr-003015	Amborella trichopoda	39.68	2.00e-79	290.00
IUUC-Apl-004145	Anas platyrhynchos	31.47	4.00e-44	171.00
IUUC-Aca-004314	Anolis carolinensis	29.16	7.00e-36	144.00
IUUC-Aly-005494	Arabidopsis lyrata	40.87	1.00e-167	582.00
IUUC-Ath-007211	Arabidopsis thaliana	39.96	1.00e-172	599.00
IUUC-Ame-011659	Astyanax mexicanus	34.51	8.00e-28	117.00
IUUC-Bta-013362	Bos taurus	28.06	3.00e-35	142.00
IUUC-Bdi-014465	Brachypodium distachyon	38.98	3.00e-60	225.00
IUUC-Bol-015853	Brassica oleracea	51.88	4.00e-91	328.00
IUUC-Bra-016751	Brassica rapa	47.95	3.00e-86	312.00
IUUC-Cja-019177	Callithrix jacchus	29.56	7.00e-38	151.00
IUUC-Cfa-020051	Canis familiaris	29.77	8.00e-37	147.00
IUUC-Cpo-021886	Cavia porcellus	29.95	3.00e-41	162.00
IUUC-Csa-024103	Chlorocebus sabaeus	29.35	3.00e-37	149.00
IUUC-Cho-024315	Choloepus hoffmanni	40.68	3.00e-19	89.40
IUUC-Csv-026075	Ciona savignyi	32.86	4.00e-19	88.60
IUUC-Cme-027348	Cyanidioschyzon merolae	37.31	3.00e-19	89.40
IUUC-Dre-028388	Danio rerio	38.07	3.00e-29	122.00
IUUC-Dno-029409	Dasypus novemcinctus	30.20	3.00e-38	152.00
IUUC-Dor-030438	Dipodomys ordii	35.18	3.00e-26	112.00
IUUC-Ete-032807	Echinops telfairi	26.21	6.00e-27	114.00
IUUC-Eca-033479	Equus caballus	28.79	3.00e-37	149.00
IUUC-Eeu-034835	Erinaceus europaeus	40.27	4.00e-25	108.00
IUUC-Fca-036320	Felis catus	30.38	2.00e-37	149.00
IUUC-Fal-037029	Ficedula albicollis	30.39	6.00e-38	151.00
IUUC-Gmo-039480	Gadus morhua	29.32	7.00e-34	137.00
IUUC-Gga-040527	Gallus gallus	30.65	7.00e-39	154.00
IUUC-Gac-042343	Gasterosteus aculeatus	28.85	2.00e-39	155.00
IUUC-Ggo-045598	Gorilla gorilla	28.76	3.00e-36	146.00
IUUC-Hsa-046598	Homo sapiens	28.76	1.00e-36	147.00
IUUC-Hvu-047146	Hordeum vulgare	40.81	1.00e-56	214.00
IUUC-Itr-047951	Ictidomys tridecemlineatus	28.92	1.00e-38	154.00
IUUC-Lch-050536	Latimeria chalumnae	29.09	2.00e-38	153.00
IUUC-Lpe-050703	Leersia perrieri	41.54	1.00e-57	217.00
IUUC-Loc-051814	Lepisosteus oculatus	28.57	3.00e-36	145.00
IUUC-Laf-053732	Loxodonta africana	28.61	2.00e-37	150.00
IUUC-Mcc-054661	Macaca mulatta	29.35	3.00e-37	149.00
IUUC-Meu-055967	Macropus eugenii	27.11	8.00e-30	124.00
IUUC-Mtr-057945	Medicago truncatula	41.78	0.00e+00	675.00
IUUC-Mga-059551	Meleagris gallopavo	31.51	4.00e-41	162.00
IUUC-Mmr-061747	Microcebus murinus	29.17	1.00e-37	150.00
IUUC-Mdo-062220	Monodelphis domestica	30.46	1.00e-38	154.00
IUUC-Mmu-063582	Mus musculus	29.34	5.00e-38	152.00
IUUC-Mac-064941	Musa acuminata	40.50	3.00e-71	261.00
IUUC-Mpu-066339	Mustela putorius furo	28.61	4.00e-36	145.00
IUUC-Mlu-067511	Myotis lucifugus	30.38	3.00e-38	152.00
IUUC-Nle-069252	Nomascus leucogenys	29.35	2.00e-37	149.00
IUUC-Opr-070969	Ochotona princeps	29.11	2.00e-37	149.00
IUUC-Ont-071786	Oreochromis niloticus	28.85	4.00e-37	149.00
IUUC-Oan-073656	Ornithorhynchus anatinus	28.97	2.00e-37	149.00
IUUC-Ocu-074704	Oryctolagus cuniculus	29.78	2.00e-37	150.00
IUUC-Oba-075094	Oryza barthii	42.28	2.00e-58	219.00
IUUC-Obr-076743	Oryza brachyantha	41.18	5.00e-56	212.00
IUUC-Ogl-077739	Oryza glaberrima	42.28	9.00e-59	220.00
IUUC-Ogu-078851	Oryza glumaepatula	42.28	2.00e-58	219.00
IUUC-Oin-079402	Oryza indica	42.28	2.00e-58	219.00
IUUC-Olo-080431	Oryza longistaminata	42.28	2.00e-58	220.00
IUUC-Ome-081580	Oryza meridionalis	42.65	1.00e-58	220.00
IUUC-Oni-082644	Oryza nivara	42.28	2.00e-58	219.00
IUUC-Opu-083452	Oryza punctata	41.91	5.00e-58	218.00
IUUC-Oru-084546	Oryza rufipogon	42.28	2.00e-58	219.00
IUUC-Osa-085858	Oryza sativa	42.28	2.00e-58	219.00
IUUC-Ola-086795	Oryzias latipes	28.25	5.00e-36	145.00
IUUC-Oga-088713	Otolemur garnettii	29.16	5.00e-37	148.00
IUUC-Oar-089887	Ovis aries	28.64	3.00e-35	142.00
IUUC-Ptr-091670	Pan troglodytes	28.76	3.00e-36	145.00
IUUC-Pan-092293	Papio anubis	29.35	3.00e-37	149.00
IUUC-Psi-093101	Pelodiscus sinensis	29.64	1.00e-37	150.00
IUUC-Ppa-095622	Physcomitrella patens	34.16	9.00e-49	188.00
IUUC-Pfo-097202	Poecilia formosa	29.21	6.00e-40	158.00
IUUC-Pab-098539	Pongo abelii	29.32	2.00e-35	142.00
IUUC-Pca-100610	Procavia capensis	27.47	2.00e-25	109.00
IUUC-Pva-102985	Pteropus vampyrus	27.40	1.00e-27	117.00
IUUC-Rno-105237	Rattus norvegicus	28.43	2.00e-37	149.00
IUUC-Sha-106889	Sarcophilus harrisii	29.23	5.00e-34	138.00
IUUC-Sja-107712	Schizosaccharomyces japonicus	36.73	2.00e-20	92.80
IUUC-Spo-108149	Schizosaccharomyces pombe	38.12	2.00e-25	109.00
IUUC-Smo-108942	Selaginella moellendorffii	50.00	4.00e-41	160.00
IUUC-Sly-111491	Solanum lycopersicum	91.69	0.00e+00	1780.00
IUUC-Sar-113530	Sorex araneus	29.19	1.00e-37	150.00
IUUC-Ssc-116091	Sus scrofa	29.05	2.00e-36	146.00
IUUC-Tgu-117478	Taeniopygia guttata	31.88	4.00e-38	152.00
IUUC-Tru-118640	Takifugu rubripes	29.21	3.00e-41	162.00
IUUC-Tsy-118869	Tarsius syrichta	30.19	7.00e-29	121.00
IUUC-Tni-120015	Tetraodon nigroviridis	28.83	1.00e-38	154.00
IUUC-Tca-121701	Theobroma cacao	46.98	1.00e-178	619.00
IUUC-Tae-125785	Triticum aestivum	32.39	2.00e-54	206.00
IUUC-Tur-126788	Triticum urartu	33.91	4.00e-54	205.00
IUUC-Tbe-128041	Tupaia belangeri	35.35	5.00e-28	118.00
IUUC-Ttr-128271	Tursiops truncatus	29.11	1.00e-36	147.00
IUUC-Vpa-130674	Vicugna pacos	29.41	4.00e-37	148.00
IUUC-Vvi-131230	Vitis vinifera	77.05	1.00e-24	102.00
IUUC-Xtr-131869	Xenopus tropicalis	29.30	9.00e-39	154.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence