iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012841

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02012154

Gene Name

UBE3C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000008025.5	ENSBTAT00000010553.5	ENSBTAP00000010553.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.40e-104	350.2	748	1085

Active Site

Position(s)	Description	Evidence
1053	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f++++++    +p+ ++ + +    ++++flGr+lgkal++
   Q: 748  PDLKKRIRVHLLNahgldEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGD-AFARHYYFLGRMLGKALYE 833
           689**********99**9************************************9999999999965.99***************** PP
   S: 85   grlldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + l++lp++ +f+++llg+  ++++++l+++dpe+y++l ++k++ e d+eelgl++t+   ++ lge++++eLk+gG++ipVt +N
   Q: 834  NMLVELPFAGFFLSKLLGTsaDVDIHHLASLDPEVYRNLLFLKSY-EGDVEELGLNFTVV--NNDLGEAQVVELKSGGKDIPVTSAN 917
           ******************9666889******************99.78999987777765..888********************** PP
   S: 170  keeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
           + +Y++lv++yrl+++i+ ++ afr+G+ +v++le+l++F+++e+++li+G    i++edlk++t+y ggy++++p+i+ Fw+v+e+
   Q: 918  RIAYIHLVADYRLNRQIRPHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAqVPISLEDLKSFTNYSGGYSAEHPVIKVFWRVVEG 1004
           ****************************************************899******************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f++ee++++L+FvT++sr Pl Gf+el p  f+i++ +sd +rlP+++TC+n+LkLPe++ +  l++kLlyAie ++gFels
   Q: 1005 FTDEEKRKLLKFVTSCSRPPLLGFKELYPA-FCIHNGGSDlERLPTASTCMNLLKLPEFQDEALLRSKLLYAIECAAGFELS 1085
           ****************************88.*****99999**************************************985 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MFSFEGDFKT RPKVSLGGAS RKEEKASLLH RTQEERRKRE EERRRLKNAI IIQSFIRGYR 60
DRKQQCSIQR SAFDRCASLS QSGGAFPLAS GPNLTLLVRQ LLFFYRQSED SKRLIWMYQN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTAGTT TTGAGGGGGA CTTCAAAACC AGGCCCAAGG TGTCCCTGGG AGGCGCGAGC 60
CGGAAGGTAA GAGCGGCCTG CGAGCGGCGG CGCCTCGGGG CCGGGCGGGG GCGGGGCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001355	Ailuropoda melanoleuca	90.88	0.00e+00	1904.00
IUUC-Atr-002669	Amborella trichopoda	35.24	6.00e-101	362.00
IUUC-Apl-003731	Anas platyrhynchos	87.57	0.00e+00	1881.00
IUUC-Aca-005248	Anolis carolinensis	86.36	0.00e+00	1880.00
IUUC-Aly-005768	Arabidopsis lyrata	35.75	4.00e-110	392.00
IUUC-Ath-006576	Arabidopsis thaliana	29.22	1.00e-113	404.00
IUUC-Ago-007748	Ashbya gossypii	42.08	5.00e-78	286.00
IUUC-Acl-008158	Aspergillus clavatus	38.59	3.00e-78	287.00
IUUC-Afl-008398	Aspergillus flavus	35.07	9.00e-80	292.00
IUUC-Afu-008937	Aspergillus fumigatus	39.28	1.00e-80	295.00
IUUC-Ani-009252	Aspergillus nidulans	38.59	3.00e-82	300.00
IUUC-Ang-009773	Aspergillus niger	34.60	6.00e-80	292.00
IUUC-Aor-009940	Aspergillus oryzae	35.07	9.00e-80	292.00
IUUC-Ate-010395	Aspergillus terreus	35.65	3.00e-80	293.00
IUUC-Ame-010769	Astyanax mexicanus	62.84	0.00e+00	1046.00
IUUC-Bgr-012269	Blumeria graminis	38.04	2.00e-75	276.00
IUUC-Bci-013743	Botrytis cinerea	38.76	3.00e-84	307.00
IUUC-Bdi-014123	Brachypodium distachyon	46.57	7.00e-103	368.00
IUUC-Bol-015390	Brassica oleracea	34.97	1.00e-102	367.00
IUUC-Bra-016853	Brassica rapa	35.07	2.00e-109	390.00
IUUC-Cel-018638	Caenorhabditis elegans	39.37	6.00e-90	325.00
IUUC-Cja-019743	Callithrix jacchus	91.19	0.00e+00	1918.00
IUUC-Cfa-021031	Canis familiaris	92.29	0.00e+00	1959.00
IUUC-Cpo-022401	Cavia porcellus	90.32	0.00e+00	1920.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	44.50	2.00e-86	312.00
IUUC-Csa-024107	Chlorocebus sabaeus	93.18	0.00e+00	1977.00
IUUC-Cho-024750	Choloepus hoffmanni	81.67	0.00e+00	794.00
IUUC-Cin-025432	Ciona intestinalis	45.37	4.00e-99	354.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	34.67	3.00e-89	323.00
IUUC-Cne-026841	Cryptococcus neoformans	36.48	8.00e-94	338.00
IUUC-Cme-027265	Cyanidioschyzon merolae	47.10	2.00e-103	370.00
IUUC-Dre-028196	Danio rerio	77.14	0.00e+00	1600.00
IUUC-Dno-029024	Dasypus novemcinctus	91.06	0.00e+00	1962.00
IUUC-Dor-030483	Dipodomys ordii	91.12	0.00e+00	685.00
IUUC-Dse-031416	Dothistroma septosporum	34.42	3.00e-79	290.00
IUUC-Dme-031946	Drosophila melanogaster	38.00	0.00e+00	683.00
IUUC-Ete-032240	Echinops telfairi	79.62	1.00e-170	593.00
IUUC-Eca-033828	Equus caballus	92.00	0.00e+00	1930.00
IUUC-Eeu-034604	Erinaceus europaeus	85.00	1.00e-126	447.00
IUUC-Fca-035907	Felis catus	91.71	0.00e+00	1968.00
IUUC-Fal-037389	Ficedula albicollis	87.83	0.00e+00	1905.00
IUUC-Fox-037788	Fusarium oxysporum	37.73	6.00e-94	338.00
IUUC-Fso-038088	Fusarium solani	36.38	2.00e-91	330.00
IUUC-Gmo-039254	Gadus morhua	66.20	0.00e+00	1224.00
IUUC-Ggr-039941	Gaeumannomyces graminis	33.57	4.00e-82	300.00
IUUC-Gga-040310	Gallus gallus	87.65	0.00e+00	1897.00
IUUC-Gac-042054	Gasterosteus aculeatus	68.76	0.00e+00	1291.00
IUUC-Gma-042836	Glycine max	35.94	5.00e-103	369.00
IUUC-Ggo-045031	Gorilla gorilla	93.36	0.00e+00	1981.00
IUUC-Hsa-045880	Homo sapiens	93.27	0.00e+00	1979.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	81.37	0.00e+00	653.00
IUUC-Kpa-049307	Komagataella pastoris	36.52	3.00e-65	243.00
IUUC-Lch-050403	Latimeria chalumnae	80.71	0.00e+00	1665.00
IUUC-Lpe-051428	Leersia perrieri	46.40	5.00e-97	349.00
IUUC-Loc-052218	Lepisosteus oculatus	80.68	0.00e+00	1702.00
IUUC-Lma-053096	Leptosphaeria maculans	38.79	1.00e-81	298.00
IUUC-Laf-054162	Loxodonta africana	87.60	0.00e+00	1659.00
IUUC-Mcc-055127	Macaca mulatta	93.09	0.00e+00	1975.00
IUUC-Meu-056187	Macropus eugenii	81.74	3.00e-105	376.00
IUUC-Mor-057021	Magnaporthe oryzae	34.49	3.00e-79	290.00
IUUC-Mpo-057570	Magnaporthe poae	36.24	1.00e-75	278.00
IUUC-Mtr-058154	Medicago truncatula	35.71	8.00e-107	381.00
IUUC-Mla-059124	Melampsora laricipopulina	48.28	7.00e-103	367.00
IUUC-Mga-059581	Meleagris gallopavo	87.21	0.00e+00	1878.00
IUUC-Mvi-060445	Microbotryum violaceum	38.22	1.00e-106	381.00
IUUC-Mmr-061360	Microcebus murinus	88.76	0.00e+00	1826.00
IUUC-Mdo-062194	Monodelphis domestica	84.68	0.00e+00	1887.00
IUUC-Mmu-064189	Mus musculus	90.14	0.00e+00	1944.00
IUUC-Mac-065275	Musa acuminata	50.61	1.00e-111	397.00
IUUC-Mpu-066439	Mustela putorius furo	90.83	0.00e+00	1899.00
IUUC-Mlu-068228	Myotis lucifugus	88.47	0.00e+00	1888.00
IUUC-Nfi-068280	Neosartorya fischeri	39.28	8.00e-81	295.00
IUUC-Ncr-068869	Neurospora crassa	36.19	1.00e-84	308.00
IUUC-Nle-069687	Nomascus leucogenys	92.94	0.00e+00	1927.00
IUUC-Opr-070592	Ochotona princeps	75.97	5.00e-123	435.00
IUUC-Ont-071836	Oreochromis niloticus	77.51	0.00e+00	1652.00
IUUC-Oan-072800	Ornithorhynchus anatinus	88.48	0.00e+00	1901.00
IUUC-Ocu-074587	Oryctolagus cuniculus	92.53	0.00e+00	1986.00
IUUC-Ola-087209	Oryzias latipes	76.77	0.00e+00	1613.00
IUUC-Olu-087699	Ostreococcus lucimarinus	43.13	2.00e-87	316.00
IUUC-Oga-088776	Otolemur garnettii	88.11	0.00e+00	1803.00
IUUC-Oar-089441	Ovis aries	98.34	0.00e+00	2040.00
IUUC-Ptr-091273	Pan troglodytes	93.27	0.00e+00	1977.00
IUUC-Pan-091981	Papio anubis	93.18	0.00e+00	1978.00
IUUC-Psi-093203	Pelodiscus sinensis	86.34	0.00e+00	1641.00
IUUC-Pma-094738	Petromyzon marinus	65.78	0.00e+00	1347.00
IUUC-Pno-095132	Phaeosphaeria nodorum	34.92	4.00e-58	219.00
IUUC-Ppa-095682	Physcomitrella patens	36.47	3.00e-112	399.00
IUUC-Pfo-097511	Poecilia formosa	77.33	0.00e+00	1652.00
IUUC-Pab-098634	Pongo abelii	90.15	0.00e+00	1897.00
IUUC-Pop-099574	Populus trichocarpa	42.27	3.00e-96	346.00
IUUC-Pca-100987	Procavia capensis	97.39	0.00e+00	785.00
IUUC-Ppe-102040	Prunus persica	34.73	2.00e-97	350.00
IUUC-Pva-103034	Pteropus vampyrus	88.05	0.00e+00	1813.00
IUUC-Pgr-103513	Puccinia graminis	39.18	2.00e-107	384.00
IUUC-Ptt-103967	Puccinia triticina	41.12	3.00e-95	343.00
IUUC-Pte-104105	Pyrenophora teres	34.43	2.00e-82	300.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	37.80	6.00e-80	292.00
IUUC-Rno-105380	Rattus norvegicus	88.80	0.00e+00	1684.00
IUUC-Sce-106446	Saccharomyces cerevisiae	40.91	1.00e-68	254.00
IUUC-Sha-107108	Sarcophilus harrisii	80.96	0.00e+00	1732.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	42.96	2.00e-95	343.00
IUUC-Spo-108097	Schizosaccharomyces pombe	44.36	2.00e-94	340.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	30.48	2.00e-84	307.00
IUUC-Smo-109537	Selaginella moellendorffii	37.22	3.00e-106	379.00
IUUC-Sit-110457	Setaria italica	48.53	4.00e-100	359.00
IUUC-Sly-111362	Solanum lycopersicum	35.97	1.00e-102	368.00
IUUC-Sar-113687	Sorex araneus	82.82	0.00e+00	919.00
IUUC-Sre-115038	Sporisorium reilianum	44.47	1.00e-98	354.00
IUUC-Ssc-116168	Sus scrofa	88.70	0.00e+00	827.00
IUUC-Tgu-116729	Taeniopygia guttata	87.66	0.00e+00	1889.00
IUUC-Tru-118068	Takifugu rubripes	76.22	0.00e+00	1612.00
IUUC-Tsy-118942	Tarsius syrichta	90.60	0.00e+00	696.00
IUUC-Tni-120732	Tetraodon nigroviridis	74.91	0.00e+00	1551.00
IUUC-Tca-121737	Theobroma cacao	35.53	2.00e-108	387.00
IUUC-Tre-121892	Trichoderma reesei	36.94	9.00e-91	328.00
IUUC-Tvi-122354	Trichoderma virens	35.88	5.00e-92	332.00
IUUC-Tme-127102	Tuber melanosporum	36.24	3.00e-93	337.00
IUUC-Tbe-127351	Tupaia belangeri	79.31	0.00e+00	1489.00
IUUC-Ttr-129061	Tursiops truncatus	90.97	0.00e+00	1911.00
IUUC-Uma-129343	Ustilago maydis	44.47	3.00e-99	356.00
IUUC-Vda-129748	Verticillium dahliae	38.82	3.00e-81	296.00
IUUC-Vvi-131234	Vitis vinifera	35.48	8.00e-105	375.00
IUUC-Xtr-132094	Xenopus tropicalis	83.62	0.00e+00	1764.00
IUUC-Xma-133923	Xiphophorus maculatus	77.42	0.00e+00	1652.00
IUUC-Yli-134496	Yarrowia lipolytica	40.16	7.00e-91	328.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence