iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074587

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02056774

Gene Name

UBE3C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000012490.3	ENSOCUT00000012499.3	ENSOCUP00000010761.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.00e-104	349.6	746	1083

Active Site

Position(s)	Description	Evidence
1051	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f++++++    +p+ ++ + +    ++++flGr+lgkal++
   Q: 746  PDLKKRIRVHLLNahgldEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGD-SFARHYYFLGRMLGKALYE 831
           689**********99**9************************************9999999999965.999**************** PP
   S: 85   grlldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + l++lp++ +f+++llg+  ++++++l+++dpe+yk+l ++k++ e d+eelgl++t+   ++ lge++++eLk gG++ipVt +N
   Q: 832  NMLVELPFAGFFLSKLLGTsaDVDIHHLASLDPEVYKNLLFLKSY-EGDVEELGLNFTVV--NNDLGEAQVVELKFGGKDIPVTSAN 915
           ******************9666889******************99.78999987777765..888********************** PP
   S: 170  keeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
           + +Y++lv++yrl+++i+ ++ afr+G+ +v++le+l++F+++e+++li+G    i++edlk++t+y ggy++d+p+i+ Fw+v+e+
   Q: 916  RIAYIHLVADYRLNKQIRPHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAqVPISLEDLKSFTNYSGGYSADHPVIKLFWRVVEG 1002
           ****************************************************899******************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f++ee++++L+FvT++sr Pl Gf+el p  f+i++ +sd +rlP+++TC+n+LkLPe+  ++ l++kLlyAie ++gFels
   Q: 1003 FTDEEKRKLLKFVTSCSRPPLLGFKELYPA-FCIHNGGSDlERLPTASTCMNLLKLPEFYDETLLRSKLLYAIECAAGFELS 1083
           ****************************88.*****99999**************************************985 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MFSFEGDFKT RPKVSLGGAS RKEEKASLLH RTQEERRKRE EERRRLKNAI IIQSFIRGYR 60
DRKQQYSIQR SAFDRCANLS QSGGTFPIAN GPNLTLLVRQ LLFFYKQNED SKRLIWLYQN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTGTGCACA AGGGTTGTGT ATATGCGCTA TGCATACATG ACATATATGA TATATACATG 60
CTTATGCATG TGTATACGGT AAATATTTGT GTGGCTATGT GTGGTATGAT ATATATCACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0000209--P:protein polyubiquitination

KEGG

ocu:100352014

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001355	Ailuropoda melanoleuca	93.66	0.00e+00	1950.00
IUUC-Apl-003731	Anas platyrhynchos	91.24	0.00e+00	1942.00
IUUC-Aca-005248	Anolis carolinensis	89.58	0.00e+00	1948.00
IUUC-Aly-005768	Arabidopsis lyrata	35.29	5.00e-108	385.00
IUUC-Ath-006576	Arabidopsis thaliana	33.38	2.00e-108	387.00
IUUC-Ago-007748	Ashbya gossypii	41.84	6.00e-77	282.00
IUUC-Acl-008158	Aspergillus clavatus	38.59	3.00e-77	283.00
IUUC-Afl-008398	Aspergillus flavus	34.19	5.00e-79	289.00
IUUC-Afu-008937	Aspergillus fumigatus	35.05	5.00e-81	296.00
IUUC-Ani-009252	Aspergillus nidulans	38.38	5.00e-81	296.00
IUUC-Ang-009773	Aspergillus niger	34.42	4.00e-79	290.00
IUUC-Aor-009940	Aspergillus oryzae	34.19	7.00e-79	289.00
IUUC-Ate-010395	Aspergillus terreus	39.23	1.00e-77	285.00
IUUC-Ame-010769	Astyanax mexicanus	63.15	0.00e+00	1050.00
IUUC-Bgr-012269	Blumeria graminis	37.83	2.00e-74	273.00
IUUC-Bta-012841	Bos taurus	92.81	0.00e+00	1967.00
IUUC-Bci-013743	Botrytis cinerea	29.94	8.00e-86	312.00
IUUC-Bol-015390	Brassica oleracea	45.87	2.00e-100	360.00
IUUC-Bra-016853	Brassica rapa	35.28	3.00e-107	382.00
IUUC-Cel-018638	Caenorhabditis elegans	40.10	5.00e-91	329.00
IUUC-Cja-019743	Callithrix jacchus	94.80	0.00e+00	1971.00
IUUC-Cfa-021031	Canis familiaris	95.13	0.00e+00	2010.00
IUUC-Cpo-022401	Cavia porcellus	94.00	0.00e+00	1989.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	44.25	3.00e-85	308.00
IUUC-Csa-024107	Chlorocebus sabaeus	97.32	0.00e+00	2043.00
IUUC-Cho-024750	Choloepus hoffmanni	83.33	0.00e+00	807.00
IUUC-Cin-025432	Ciona intestinalis	44.63	2.00e-97	349.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	34.49	5.00e-88	319.00
IUUC-Cne-026841	Cryptococcus neoformans	35.52	2.00e-94	340.00
IUUC-Cme-027265	Cyanidioschyzon merolae	46.86	1.00e-102	367.00
IUUC-Dre-028196	Danio rerio	78.32	0.00e+00	1617.00
IUUC-Dno-029024	Dasypus novemcinctus	95.85	0.00e+00	2028.00
IUUC-Dor-030483	Dipodomys ordii	92.43	0.00e+00	694.00
IUUC-Dse-031416	Dothistroma septosporum	34.25	1.00e-78	288.00
IUUC-Dme-031946	Drosophila melanogaster	36.95	0.00e+00	673.00
IUUC-Ete-032240	Echinops telfairi	86.02	3.00e-178	619.00
IUUC-Eca-033828	Equus caballus	95.57	0.00e+00	1995.00
IUUC-Eeu-034604	Erinaceus europaeus	85.77	1.00e-127	450.00
IUUC-Fca-035907	Felis catus	94.00	0.00e+00	2008.00
IUUC-Fal-037389	Ficedula albicollis	91.33	0.00e+00	1973.00
IUUC-Fox-037788	Fusarium oxysporum	37.79	9.00e-94	338.00
IUUC-Fso-038088	Fusarium solani	36.38	4.00e-90	326.00
IUUC-Gmo-039254	Gadus morhua	67.57	0.00e+00	1244.00
IUUC-Ggr-039941	Gaeumannomyces graminis	34.45	8.00e-84	305.00
IUUC-Gga-040310	Gallus gallus	90.87	0.00e+00	1959.00
IUUC-Gac-042054	Gasterosteus aculeatus	70.30	0.00e+00	1317.00
IUUC-Gma-042836	Glycine max	33.83	7.00e-102	365.00
IUUC-Ggo-045031	Gorilla gorilla	97.69	0.00e+00	2051.00
IUUC-Hsa-045880	Homo sapiens	97.60	0.00e+00	2050.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	91.00	0.00e+00	713.00
IUUC-Kpa-049307	Komagataella pastoris	36.75	5.00e-65	243.00
IUUC-Lch-050403	Latimeria chalumnae	82.13	0.00e+00	1698.00
IUUC-Loc-052218	Lepisosteus oculatus	81.95	0.00e+00	1723.00
IUUC-Lma-053096	Leptosphaeria maculans	38.58	2.00e-80	294.00
IUUC-Laf-054162	Loxodonta africana	91.52	0.00e+00	1713.00
IUUC-Mcc-055127	Macaca mulatta	97.41	0.00e+00	2044.00
IUUC-Meu-056187	Macropus eugenii	83.04	5.00e-106	379.00
IUUC-Mor-057021	Magnaporthe oryzae	34.84	2.00e-79	290.00
IUUC-Mpo-057570	Magnaporthe poae	36.68	4.00e-76	280.00
IUUC-Mtr-058154	Medicago truncatula	30.01	2.00e-106	380.00
IUUC-Mla-059124	Melampsora laricipopulina	48.28	4.00e-102	364.00
IUUC-Mga-059581	Meleagris gallopavo	90.91	0.00e+00	1947.00
IUUC-Mvi-060445	Microbotryum violaceum	37.79	7.00e-105	375.00
IUUC-Mmr-061360	Microcebus murinus	92.34	0.00e+00	1894.00
IUUC-Mdo-062194	Monodelphis domestica	88.21	0.00e+00	1957.00
IUUC-Mmu-064189	Mus musculus	93.81	0.00e+00	2017.00
IUUC-Mac-065275	Musa acuminata	49.39	9.00e-109	387.00
IUUC-Mpu-066439	Mustela putorius furo	93.07	0.00e+00	1930.00
IUUC-Mlu-068228	Myotis lucifugus	89.75	0.00e+00	1920.00
IUUC-Nfi-068280	Neosartorya fischeri	39.07	6.00e-80	292.00
IUUC-Ncr-068869	Neurospora crassa	35.96	8.00e-83	302.00
IUUC-Nle-069687	Nomascus leucogenys	96.98	0.00e+00	1989.00
IUUC-Opr-070592	Ochotona princeps	80.52	4.00e-131	462.00
IUUC-Ont-071836	Oreochromis niloticus	78.58	0.00e+00	1662.00
IUUC-Oan-072800	Ornithorhynchus anatinus	91.33	0.00e+00	1962.00
IUUC-Ola-087209	Oryzias latipes	78.30	0.00e+00	1637.00
IUUC-Olu-087699	Ostreococcus lucimarinus	42.86	1.00e-86	313.00
IUUC-Oga-088776	Otolemur garnettii	91.32	0.00e+00	1857.00
IUUC-Oar-089441	Ovis aries	91.71	0.00e+00	1944.00
IUUC-Ptr-091273	Pan troglodytes	97.51	0.00e+00	2047.00
IUUC-Pan-091981	Papio anubis	97.32	0.00e+00	2043.00
IUUC-Psi-093203	Pelodiscus sinensis	89.74	0.00e+00	1695.00
IUUC-Pma-094738	Petromyzon marinus	65.06	0.00e+00	1339.00
IUUC-Pno-095132	Phaeosphaeria nodorum	29.98	6.00e-61	229.00
IUUC-Ppa-095682	Physcomitrella patens	35.71	3.00e-113	402.00
IUUC-Pfo-097511	Poecilia formosa	78.67	0.00e+00	1679.00
IUUC-Pab-098634	Pongo abelii	94.46	0.00e+00	1967.00
IUUC-Pop-099574	Populus trichocarpa	41.65	1.00e-94	341.00
IUUC-Pca-100987	Procavia capensis	85.95	0.00e+00	864.00
IUUC-Ppe-102040	Prunus persica	30.19	1.00e-98	354.00
IUUC-Pva-103034	Pteropus vampyrus	89.27	0.00e+00	1837.00
IUUC-Pgr-103513	Puccinia graminis	39.18	9.00e-107	381.00
IUUC-Ptt-103967	Puccinia triticina	41.32	1.00e-94	341.00
IUUC-Pte-104105	Pyrenophora teres	34.38	2.00e-81	297.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	34.38	4.00e-80	293.00
IUUC-Rno-105380	Rattus norvegicus	93.35	0.00e+00	1758.00
IUUC-Sce-106446	Saccharomyces cerevisiae	41.01	6.00e-68	252.00
IUUC-Sha-107108	Sarcophilus harrisii	84.62	0.00e+00	1792.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	43.89	1.00e-94	341.00
IUUC-Spo-108097	Schizosaccharomyces pombe	44.61	2.00e-94	340.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	30.35	2.00e-83	304.00
IUUC-Sar-113687	Sorex araneus	82.30	0.00e+00	918.00
IUUC-Sre-115038	Sporisorium reilianum	44.72	6.00e-98	352.00
IUUC-Ssc-116168	Sus scrofa	88.68	0.00e+00	822.00
IUUC-Tgu-116729	Taeniopygia guttata	91.15	0.00e+00	1956.00
IUUC-Tru-118068	Takifugu rubripes	77.47	0.00e+00	1626.00
IUUC-Tsy-118942	Tarsius syrichta	98.31	0.00e+00	736.00
IUUC-Tni-120732	Tetraodon nigroviridis	76.63	0.00e+00	1569.00
IUUC-Tre-121892	Trichoderma reesei	37.30	1.00e-89	325.00
IUUC-Tvi-122354	Trichoderma virens	35.68	8.00e-91	328.00
IUUC-Tme-127102	Tuber melanosporum	36.03	2.00e-92	333.00
IUUC-Tbe-127351	Tupaia belangeri	82.24	0.00e+00	1551.00
IUUC-Ttr-129061	Tursiops truncatus	91.24	0.00e+00	1907.00
IUUC-Uma-129343	Ustilago maydis	44.72	5.00e-99	355.00
IUUC-Vda-129748	Verticillium dahliae	38.82	6.00e-81	295.00
IUUC-Vvi-131234	Vitis vinifera	30.20	1.00e-106	381.00
IUUC-Xtr-132094	Xenopus tropicalis	86.19	0.00e+00	1801.00
IUUC-Xma-133923	Xiphophorus maculatus	78.95	0.00e+00	1682.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence