iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066584

Ensembl Protein ID

ENSMPUP00000002112.1

UniProt Accession

M3XSR2; M3XSR2_MUSPF

Genbank Protein ID

ENSMPUP00000002112

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01081014

Gene Name

FBXL5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000002133.1	ENSMPUT00000002155.1	ENSMPUP00000002112.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	6.20e-06	26.3	200	248

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 98   pdaglldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
            +a+ +++lp e++++i+++l+++el+r+++v+ +w++la++ +lwk++
   Q: 200  EQATGITHLPPEVMLSIFSYLNPQELCRCSQVSTKWSQLAKTGSLWKHL 248
           56677899*********************************9****987 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MAPFPEEVDV FTAPHWRMKQ LVGLYCDKLS KTNFSNNNDF RALLQSLYAT FKEFKMHEQI 60
ENEYIIGLLQ QRSQTIYNVH SDNKLSEMLS LFEKGLKNVK NECEQLNYAK QLKERLEAFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCCCT TCCCCGAAGA AGTGGACGTC TTCACCGCCC CACACTGGCG GATGAAGCAG 60
CTGGTGGGGC TCTACTGCGA CAAGGTAACG GTGTGCAGAG CCTCTTGCTC CGGGCAGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR012312--Haemerythrin-like
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF01814--Hemerythrin
PF13516--LRR_6

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0048471--C:perinuclear region of cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0005506--F:iron ion binding
GO:0055072--P:iron ion homeostasis
GO:1903364--P:positive regulation of cellular protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002319	Ailuropoda melanoleuca	97.61	0.00e+00	1217.00
IUUC-Apl-003755	Anas platyrhynchos	79.97	0.00e+00	993.00
IUUC-Aca-004798	Anolis carolinensis	78.18	0.00e+00	1045.00
IUUC-Ame-011091	Astyanax mexicanus	60.40	0.00e+00	770.00
IUUC-Bta-013204	Bos taurus	94.91	0.00e+00	1216.00
IUUC-Cja-019594	Callithrix jacchus	94.69	0.00e+00	1025.00
IUUC-Cfa-020965	Canis familiaris	98.12	0.00e+00	1271.00
IUUC-Cpo-021308	Cavia porcellus	93.34	0.00e+00	1224.00
IUUC-Csa-023865	Chlorocebus sabaeus	95.51	0.00e+00	1303.00
IUUC-Cho-024778	Choloepus hoffmanni	83.24	2.00e-164	572.00
IUUC-Dre-027628	Danio rerio	54.75	4.00e-176	611.00
IUUC-Dno-029899	Dasypus novemcinctus	93.59	0.00e+00	1271.00
IUUC-Dor-031105	Dipodomys ordii	80.98	0.00e+00	1050.00
IUUC-Ete-032314	Echinops telfairi	87.48	0.00e+00	1081.00
IUUC-Eca-033797	Equus caballus	95.60	0.00e+00	1153.00
IUUC-Eeu-034811	Erinaceus europaeus	85.39	0.00e+00	882.00
IUUC-Fca-036516	Felis catus	96.39	0.00e+00	1200.00
IUUC-Fal-036824	Ficedula albicollis	78.34	0.00e+00	929.00
IUUC-Gga-040271	Gallus gallus	81.07	0.00e+00	1066.00
IUUC-Gac-041399	Gasterosteus aculeatus	62.02	0.00e+00	792.00
IUUC-Ggo-044415	Gorilla gorilla	95.66	0.00e+00	1303.00
IUUC-Hsa-047001	Homo sapiens	95.37	0.00e+00	1317.00
IUUC-Itr-048356	Ictidomys tridecemlineatus	93.41	0.00e+00	1034.00
IUUC-Lch-049897	Latimeria chalumnae	66.14	0.00e+00	833.00
IUUC-Loc-052162	Lepisosteus oculatus	66.33	0.00e+00	859.00
IUUC-Laf-054031	Loxodonta africana	95.51	0.00e+00	1273.00
IUUC-Mcc-054680	Macaca mulatta	95.80	0.00e+00	1308.00
IUUC-Meu-056199	Macropus eugenii	84.58	9.00e-102	364.00
IUUC-Mga-059675	Meleagris gallopavo	80.45	0.00e+00	1016.00
IUUC-Mmr-061694	Microcebus murinus	95.08	0.00e+00	1293.00
IUUC-Mdo-062900	Monodelphis domestica	89.73	0.00e+00	1211.00
IUUC-Mmu-063178	Mus musculus	93.04	0.00e+00	1260.00
IUUC-Mlu-067859	Myotis lucifugus	95.78	0.00e+00	1191.00
IUUC-Nle-069172	Nomascus leucogenys	96.24	0.00e+00	1281.00
IUUC-Opr-070992	Ochotona princeps	89.78	0.00e+00	996.00
IUUC-Ont-072577	Oreochromis niloticus	61.72	0.00e+00	788.00
IUUC-Oan-072870	Ornithorhynchus anatinus	85.41	0.00e+00	903.00
IUUC-Ocu-074849	Oryctolagus cuniculus	91.75	0.00e+00	1226.00
IUUC-Ola-087146	Oryzias latipes	60.00	0.00e+00	765.00
IUUC-Oga-088307	Otolemur garnettii	94.01	0.00e+00	1221.00
IUUC-Oar-090192	Ovis aries	92.92	0.00e+00	1228.00
IUUC-Ptr-091049	Pan troglodytes	95.95	0.00e+00	1308.00
IUUC-Pan-091995	Papio anubis	95.66	0.00e+00	1306.00
IUUC-Psi-093154	Pelodiscus sinensis	80.38	0.00e+00	989.00
IUUC-Pma-094334	Petromyzon marinus	46.70	6.00e-138	484.00
IUUC-Pfo-096154	Poecilia formosa	61.30	0.00e+00	768.00
IUUC-Pab-098264	Pongo abelii	94.73	0.00e+00	1247.00
IUUC-Pca-100884	Procavia capensis	74.35	0.00e+00	939.00
IUUC-Pva-102114	Pteropus vampyrus	95.23	0.00e+00	1282.00
IUUC-Rno-105392	Rattus norvegicus	94.06	0.00e+00	1273.00
IUUC-Sha-106508	Sarcophilus harrisii	86.65	0.00e+00	1152.00
IUUC-Stu-112725	Solanum tuberosum	32.20	1.00e-04	41.20
IUUC-Sar-113107	Sorex araneus	90.53	0.00e+00	828.00
IUUC-Ssc-115489	Sus scrofa	96.67	0.00e+00	1251.00
IUUC-Tgu-116734	Taeniopygia guttata	79.21	0.00e+00	1014.00
IUUC-Tru-117632	Takifugu rubripes	60.73	0.00e+00	774.00
IUUC-Tsy-119400	Tarsius syrichta	93.97	0.00e+00	1194.00
IUUC-Tni-120602	Tetraodon nigroviridis	59.92	0.00e+00	790.00
IUUC-Tbe-127833	Tupaia belangeri	91.86	0.00e+00	628.00
IUUC-Ttr-129289	Tursiops truncatus	95.40	0.00e+00	744.00
IUUC-Vpa-130253	Vicugna pacos	96.13	0.00e+00	641.00
IUUC-Vvi-131468	Vitis vinifera	32.39	2.00e-05	43.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence