iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033801

Ensembl Protein ID

ENSECAP00000019317.1

UniProt Accession

F6X4S0; F6X4S0_HORSE

Protein Name

Uncharacterized protein

Gene Name

CTTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000021450.1	ENSECAT00000023332.1	ENSECAP00000019317.1
ENSECAG00000021450.1	ENSECAT00000023407.1	ENSECAP00000019385.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.80e-13	48.0	499	548

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           ++lydy+a+ dde ++   d+++ i  e  d gW++g    +g+ GlfP+n+ve
   Q: 499  IALYDYQAAGDDEISFDPDDIITNI--EMIDDGWWRG--LCKGRYGLFPANYVE 548
           79***********************..9*********..9************97 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

LLFQMWKASA GHAVSLSQDD GGADDWETDP DFVNDVSEKE QRWGAKTVQG SGHQEHINIH 60
KLRENVFQEH QTLKEKELET GPRASHGYGG KFGVEQDRMD KSAVGHEYQS KLSKHCSQVD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCTCTTCC AGATGTGGAA AGCTTCAGCC GGCCACGCTG TGTCCCTCAG CCAGGACGAT 60
GGGGGAGCCG ACGACTGGGA AACCGACCCC GATTTTGTGG TATGACTCTC CGCCTACCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015503--Cortactin
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005884--C:actin filament
GO:0030863--C:cortical cytoskeleton
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0030027--C:lamellipodium
GO:1990023--C:mitotic spindle midzone
GO:0002102--C:podosome
GO:0001726--C:ruffle
GO:0008076--C:voltage-gated potassium channel complex
GO:0030041--P:actin filament polymerization
GO:0097062--P:dendritic spine maintenance
GO:0006886--P:intracellular protein transport
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:0045987--P:positive regulation of smooth muscle contraction
GO:1903146--P:regulation of mitophagy
GO:0006930--P:substrate-dependent cell migration, cell extension

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002064	Ailuropoda melanoleuca	92.01	0.00e+00	937.00
IUUC-Apl-003745	Anas platyrhynchos	84.02	0.00e+00	799.00
IUUC-Aca-004438	Anolis carolinensis	79.65	0.00e+00	860.00
IUUC-Ame-011170	Astyanax mexicanus	46.03	2.00e-110	392.00
IUUC-Bgr-012041	Blumeria graminis	57.89	1.00e-15	78.60
IUUC-Bta-013563	Bos taurus	90.33	0.00e+00	890.00
IUUC-Bci-013690	Botrytis cinerea	58.82	5.00e-12	66.60
IUUC-Cfa-020718	Canis familiaris	89.25	0.00e+00	935.00
IUUC-Cpo-022303	Cavia porcellus	88.18	0.00e+00	964.00
IUUC-Csa-023431	Chlorocebus sabaeus	91.64	0.00e+00	927.00
IUUC-Cin-025677	Ciona intestinalis	61.33	4.00e-117	415.00
IUUC-Csv-026140	Ciona savignyi	63.33	3.00e-106	378.00
IUUC-Dre-028012	Danio rerio	64.17	7.00e-179	620.00
IUUC-Dno-029332	Dasypus novemcinctus	82.00	0.00e+00	781.00
IUUC-Dme-031931	Drosophila melanogaster	62.61	4.00e-74	272.00
IUUC-Fca-035633	Felis catus	89.49	0.00e+00	762.00
IUUC-Fal-036775	Ficedula albicollis	83.27	0.00e+00	778.00
IUUC-Fox-037778	Fusarium oxysporum	59.65	1.00e-14	75.10
IUUC-Gmo-038507	Gadus morhua	56.79	8.00e-21	94.70
IUUC-Gga-040568	Gallus gallus	83.87	0.00e+00	816.00
IUUC-Gac-042253	Gasterosteus aculeatus	55.46	1.00e-112	400.00
IUUC-Hsa-046818	Homo sapiens	92.55	0.00e+00	935.00
IUUC-Itr-048833	Ictidomys tridecemlineatus	87.80	0.00e+00	864.00
IUUC-Lch-050199	Latimeria chalumnae	70.33	1.00e-144	506.00
IUUC-Loc-052855	Lepisosteus oculatus	74.44	1.00e-151	529.00
IUUC-Laf-053866	Loxodonta africana	90.40	0.00e+00	974.00
IUUC-Mcc-055515	Macaca mulatta	92.18	0.00e+00	928.00
IUUC-Mga-059791	Meleagris gallopavo	84.63	0.00e+00	811.00
IUUC-Mmr-061147	Microcebus murinus	91.85	0.00e+00	875.00
IUUC-Mdo-062660	Monodelphis domestica	62.21	3.00e-177	615.00
IUUC-Mmu-064023	Mus musculus	90.69	0.00e+00	910.00
IUUC-Mpu-065867	Mustela putorius furo	81.68	0.00e+00	798.00
IUUC-Mlu-067704	Myotis lucifugus	87.07	0.00e+00	812.00
IUUC-Ont-071873	Oreochromis niloticus	79.72	5.00e-165	574.00
IUUC-Oan-073528	Ornithorhynchus anatinus	82.79	2.00e-164	571.00
IUUC-Oga-088028	Otolemur garnettii	90.91	0.00e+00	919.00
IUUC-Oar-090203	Ovis aries	90.79	0.00e+00	815.00
IUUC-Pan-092594	Papio anubis	87.93	0.00e+00	878.00
IUUC-Psi-093389	Pelodiscus sinensis	82.60	0.00e+00	819.00
IUUC-Pma-094161	Petromyzon marinus	46.03	6.00e-82	298.00
IUUC-Pfo-097391	Poecilia formosa	54.19	5.00e-109	387.00
IUUC-Pab-097913	Pongo abelii	85.25	0.00e+00	825.00
IUUC-Rno-105489	Rattus norvegicus	89.96	0.00e+00	875.00
IUUC-Sha-107308	Sarcophilus harrisii	70.27	0.00e+00	680.00
IUUC-Sja-107956	Schizosaccharomyces japonicus	55.17	2.00e-14	74.30
IUUC-Tgu-117049	Taeniopygia guttata	77.70	0.00e+00	717.00
IUUC-Tru-118718	Takifugu rubripes	75.21	2.00e-156	545.00
IUUC-Tni-120535	Tetraodon nigroviridis	68.35	2.00e-143	502.00
IUUC-Tre-122167	Trichoderma reesei	59.18	1.00e-11	65.10
IUUC-Tvi-122614	Trichoderma virens	59.18	1.00e-11	65.50
IUUC-Vda-129766	Verticillium dahliae	57.89	1.00e-13	71.60
IUUC-Xtr-131797	Xenopus tropicalis	74.02	1.00e-151	530.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence