iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-116027

Ensembl Protein ID

ENSSSCP00000012658.2

UniProt Accession

F1SPE8; F1SPE8_PIG

Genbank Protein ID

ENSSSCP00000012658

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU861646

Gene Name

HCLS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000011884.2	ENSSSCT00000013000.2	ENSSSCP00000012658.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.50e-11	43.2	439	490

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
            +lydy+++ +de ++   d+++ i  e  degW++g    +g  GlfP+n+v+ l
   Q: 439  VALYDYQGEGSDEISFDPDDIITDI--EMVDEGWWRG--RCHGHFGLFPANYVKLL 490
           68**********************9..9*********..8*************977 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MWKSVVGHDV SVSMETQGDD WDTDPDFVND ISEKEQRWGA KTIEGSGRTE HINIHQLRNK 60
VSEEHDILKK KEMESGPKAS HGYGGRFGVE RDRMDKSAVG HEYVAEVEKH SSQTDAARGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGAATACG GAACTGAAGC AGCAGCTCAG AATTTCTTGC TCTGAAGTCG CAGCAGCTAG 60
AGAGGAGCTG AGTGTCGCTG TGAGGAGCTG AGAGCTGAGA GCTGAGAGCA AACGCTTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR028534--HS1
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005667--C:transcription factor complex
GO:0030041--P:actin filament polymerization
GO:0071345--P:cellular response to cytokine stimulus
GO:0030218--P:erythrocyte differentiation
GO:2000107--P:negative regulation of leukocyte apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0008284--P:positive regulation of cell proliferation
GO:0030854--P:positive regulation of granulocyte differentiation
GO:0045651--P:positive regulation of macrophage differentiation
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042531--P:positive regulation of tyrosine phosphorylation of STAT protein
GO:0030833--P:regulation of actin filament polymerization
GO:0009725--P:response to hormone

KEGG

ssc:100521992

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001194	Ailuropoda melanoleuca	84.54	0.00e+00	728.00
IUUC-Apl-003745	Anas platyrhynchos	57.31	9.00e-85	307.00
IUUC-Aca-004438	Anolis carolinensis	64.38	4.00e-81	295.00
IUUC-Ame-011504	Astyanax mexicanus	52.81	8.00e-79	287.00
IUUC-Bta-012591	Bos taurus	88.03	0.00e+00	714.00
IUUC-Cel-018639	Caenorhabditis elegans	68.52	1.00e-17	84.70
IUUC-Cja-019982	Callithrix jacchus	83.87	0.00e+00	678.00
IUUC-Cfa-020262	Canis familiaris	87.40	0.00e+00	649.00
IUUC-Cpo-021362	Cavia porcellus	80.08	0.00e+00	638.00
IUUC-Csa-023911	Chlorocebus sabaeus	91.22	2.00e-171	595.00
IUUC-Cin-025677	Ciona intestinalis	54.63	2.00e-65	243.00
IUUC-Csv-026140	Ciona savignyi	58.60	3.00e-63	235.00
IUUC-Dre-028127	Danio rerio	70.42	2.00e-93	336.00
IUUC-Dno-029332	Dasypus novemcinctus	64.73	6.00e-91	327.00
IUUC-Dor-030437	Dipodomys ordii	77.33	4.00e-177	613.00
IUUC-Dme-031931	Drosophila melanogaster	42.74	7.00e-72	264.00
IUUC-Ete-033160	Echinops telfairi	72.84	3.00e-151	528.00
IUUC-Eca-033269	Equus caballus	89.25	0.00e+00	745.00
IUUC-Eeu-035032	Erinaceus europaeus	73.10	2.00e-130	458.00
IUUC-Fca-035999	Felis catus	86.57	0.00e+00	776.00
IUUC-Fal-037107	Ficedula albicollis	64.44	3.00e-105	375.00
IUUC-Gmo-038507	Gadus morhua	68.52	7.00e-18	85.10
IUUC-Gga-040335	Gallus gallus	66.78	1.00e-105	376.00
IUUC-Gac-042253	Gasterosteus aculeatus	69.48	1.00e-88	320.00
IUUC-Ggo-044505	Gorilla gorilla	81.25	0.00e+00	684.00
IUUC-Hsa-046728	Homo sapiens	90.11	2.00e-170	591.00
IUUC-Itr-048592	Ictidomys tridecemlineatus	66.67	4.00e-163	567.00
IUUC-Lch-050221	Latimeria chalumnae	77.31	1.00e-99	356.00
IUUC-Loc-052855	Lepisosteus oculatus	50.94	3.00e-86	312.00
IUUC-Laf-054202	Loxodonta africana	83.03	0.00e+00	666.00
IUUC-Mcc-055824	Macaca mulatta	90.68	3.00e-171	594.00
IUUC-Mga-059791	Meleagris gallopavo	56.52	3.00e-84	305.00
IUUC-Mmr-061281	Microcebus murinus	71.81	5.00e-165	573.00
IUUC-Mdo-062515	Monodelphis domestica	67.52	7.00e-150	523.00
IUUC-Mmu-064341	Mus musculus	81.98	0.00e+00	683.00
IUUC-Mpu-066565	Mustela putorius furo	79.72	0.00e+00	660.00
IUUC-Mlu-066942	Myotis lucifugus	82.83	0.00e+00	666.00
IUUC-Nle-069436	Nomascus leucogenys	92.45	4.00e-27	115.00
IUUC-Opr-070288	Ochotona princeps	75.20	2.00e-165	575.00
IUUC-Ont-071712	Oreochromis niloticus	73.24	3.00e-91	328.00
IUUC-Oan-073528	Ornithorhynchus anatinus	41.06	7.00e-45	174.00
IUUC-Ocu-074686	Oryctolagus cuniculus	82.19	0.00e+00	627.00
IUUC-Ola-086894	Oryzias latipes	59.09	6.00e-94	337.00
IUUC-Oga-088585	Otolemur garnettii	77.53	0.00e+00	655.00
IUUC-Oar-089686	Ovis aries	87.35	0.00e+00	725.00
IUUC-Ptr-090461	Pan troglodytes	90.68	7.00e-171	593.00
IUUC-Pan-091887	Papio anubis	90.96	4.00e-172	597.00
IUUC-Psi-093785	Pelodiscus sinensis	50.45	1.00e-137	483.00
IUUC-Pma-094161	Petromyzon marinus	62.96	9.00e-56	211.00
IUUC-Pfo-097391	Poecilia formosa	68.08	6.00e-89	321.00
IUUC-Pab-098222	Pongo abelii	90.11	1.00e-169	589.00
IUUC-Pca-100668	Procavia capensis	82.38	0.00e+00	663.00
IUUC-Pva-102767	Pteropus vampyrus	74.85	3.00e-165	574.00
IUUC-Rno-106001	Rattus norvegicus	81.17	0.00e+00	685.00
IUUC-Sha-106912	Sarcophilus harrisii	92.49	3.00e-117	415.00
IUUC-Sar-113338	Sorex araneus	77.42	2.00e-174	604.00
IUUC-Tgu-117472	Taeniopygia guttata	56.47	8.00e-148	516.00
IUUC-Tru-118718	Takifugu rubripes	64.15	3.00e-84	305.00
IUUC-Tni-119931	Tetraodon nigroviridis	57.24	2.00e-93	336.00
IUUC-Tre-122167	Trichoderma reesei	57.14	2.00e-11	63.90
IUUC-Tvi-122614	Trichoderma virens	57.14	2.00e-11	64.70
IUUC-Xtr-131797	Xenopus tropicalis	68.08	2.00e-81	295.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence