iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053967

Ensembl Protein ID

ENSLAFP00000011659.3

UniProt Accession

G3TC99; G3TC99_LOXAF

Protein Name

Uncharacterized protein

Gene Name

RNF144B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000013923.3	ENSLAFT00000013927.3	ENSLAFP00000011659.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	5.90e-51	173.8	30	222

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+e+s +++t+l+eC+++fC++Clkqy++l+i++g+ + i+cp++ c ++  l+e+ei++ lv  ++++ y++l++e++v+ d+ +
   Q: 30   CKLCLCEHSLDKMTTLQECRCIFCTACLKQYMQLAIRDGCGSPITCPDMVCLNHgtLQEAEIAC-LVPVDQFQLYQRLKFEREVHLDPYR 118
           ***************************************************9988899******.6999********************* PP
   S: 89   kwcpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
           +wcp +dC++v+ +++ +  + + vec++c+ +fC++Ck++wH+++sC++ +  +  te   + a   + +ea +k+Cp C+vyie+neg
   Q: 119  TWCPVADCQTVCHVASGDpgQPVLVECPSCHLKFCSCCKDAWHAETSCRDSQSVVLPTE---HGALFGTDAEAPIKQCPVCRVYIERNEG 205
           **************998877899999***************************999999...899************************* PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m+C++Ck++fCw+C
   Q: 206  CAQMMCKNCKHTFCWYC 222
           ***************** PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MDSVGRLHYL TMTAENSTPR DLALAPLVTC KLCLCEHSLD KMTTLQECRC IFCTACLKQY 60
MQLAIRDGCG SPITCPDMVC LNHGTLQEAE IACLVPVDQF QLYQRLKFER EVHLDPYRTW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACTCAG TTGGTAGGCT CCACTATCTC ACCATGACTG CCGAAAACTC GACGCCCAGA 60
GACCTGGCTC TGGCTCCCCT GGTCACTTGC AAACTCTGCC TGTGCGAACA TTCTTTGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1

Pfam

PF01485--IBR

SMART

SM00647--IBR

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0046872--F:metal ion binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

lav:100657272

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001257	Ailuropoda melanoleuca	92.41	8.00e-167	578.00
IUUC-Apl-004112	Anas platyrhynchos	81.49	1.00e-131	462.00
IUUC-Aca-004533	Anolis carolinensis	76.90	2.00e-138	484.00
IUUC-Bta-012641	Bos taurus	93.42	8.00e-167	579.00
IUUC-Cja-019626	Callithrix jacchus	80.53	2.00e-141	494.00
IUUC-Cfa-020702	Canis familiaris	93.07	2.00e-168	584.00
IUUC-Cpo-022147	Cavia porcellus	92.74	4.00e-165	573.00
IUUC-Csa-023473	Chlorocebus sabaeus	94.39	4.00e-170	590.00
IUUC-Cho-024298	Choloepus hoffmanni	89.88	1.00e-138	485.00
IUUC-Dre-028099	Danio rerio	65.41	2.00e-91	328.00
IUUC-Dno-029122	Dasypus novemcinctus	87.50	2.00e-155	541.00
IUUC-Dor-030669	Dipodomys ordii	94.85	1.00e-132	464.00
IUUC-Ete-033141	Echinops telfairi	79.54	4.00e-130	457.00
IUUC-Eca-034360	Equus caballus	95.38	3.00e-172	597.00
IUUC-Eeu-034538	Erinaceus europaeus	73.71	6.00e-86	309.00
IUUC-Fca-036055	Felis catus	91.09	2.00e-163	568.00
IUUC-Fal-037339	Ficedula albicollis	81.00	2.00e-135	474.00
IUUC-Gmo-038780	Gadus morhua	60.66	8.00e-85	306.00
IUUC-Gga-040256	Gallus gallus	80.07	4.00e-134	470.00
IUUC-Gac-042127	Gasterosteus aculeatus	62.01	1.00e-90	325.00
IUUC-Ggo-044867	Gorilla gorilla	95.05	3.00e-171	593.00
IUUC-Hsa-046928	Homo sapiens	94.72	1.00e-170	592.00
IUUC-Hvu-047484	Hordeum vulgare	29.19	1.00e-16	80.90
IUUC-Itr-048250	Ictidomys tridecemlineatus	95.34	3.00e-108	383.00
IUUC-Lch-050168	Latimeria chalumnae	72.79	6.00e-131	459.00
IUUC-Lpe-051649	Leersia perrieri	27.80	8.00e-16	79.30
IUUC-Loc-052150	Lepisosteus oculatus	60.57	7.00e-88	316.00
IUUC-Mcc-055898	Macaca mulatta	94.39	4.00e-170	590.00
IUUC-Meu-056628	Macropus eugenii	97.44	2.00e-43	168.00
IUUC-Mtr-057989	Medicago truncatula	25.94	1.00e-17	83.60
IUUC-Mga-059820	Meleagris gallopavo	79.00	2.00e-132	464.00
IUUC-Mmr-060680	Microcebus murinus	92.41	8.00e-166	575.00
IUUC-Mdo-062839	Monodelphis domestica	85.53	2.00e-153	534.00
IUUC-Mmu-063339	Mus musculus	88.45	5.00e-150	523.00
IUUC-Mac-065414	Musa acuminata	27.96	4.00e-18	85.50
IUUC-Mpu-065973	Mustela putorius furo	91.42	6.00e-165	573.00
IUUC-Mlu-067112	Myotis lucifugus	94.72	7.00e-162	562.00
IUUC-Nle-069795	Nomascus leucogenys	94.72	9.00e-171	592.00
IUUC-Opr-070390	Ochotona princeps	87.79	2.00e-151	527.00
IUUC-Ont-072329	Oreochromis niloticus	59.51	2.00e-89	322.00
IUUC-Oan-072980	Ornithorhynchus anatinus	84.06	2.00e-138	484.00
IUUC-Ocu-073845	Oryctolagus cuniculus	94.39	1.00e-169	588.00
IUUC-Ola-086872	Oryzias latipes	60.67	8.00e-84	303.00
IUUC-Oga-088954	Otolemur garnettii	93.73	4.00e-168	583.00
IUUC-Oar-089879	Ovis aries	94.08	1.00e-167	582.00
IUUC-Ptr-090685	Pan troglodytes	94.72	1.00e-170	592.00
IUUC-Pan-092086	Papio anubis	94.06	5.00e-170	589.00
IUUC-Psi-093481	Pelodiscus sinensis	82.18	6.00e-142	496.00
IUUC-Pfo-096065	Poecilia formosa	64.02	5.00e-91	327.00
IUUC-Pab-098031	Pongo abelii	94.39	1.00e-169	588.00
IUUC-Pca-100936	Procavia capensis	93.73	4.00e-169	586.00
IUUC-Pva-102864	Pteropus vampyrus	84.16	6.00e-147	513.00
IUUC-Rno-105503	Rattus norvegicus	88.45	8.00e-150	522.00
IUUC-Sha-107425	Sarcophilus harrisii	86.51	1.00e-155	541.00
IUUC-Stu-112736	Solanum tuberosum	27.83	6.00e-18	84.30
IUUC-Ssc-115458	Sus scrofa	93.16	3.00e-157	547.00
IUUC-Tgu-117226	Taeniopygia guttata	80.65	5.00e-136	476.00
IUUC-Tru-118362	Takifugu rubripes	63.53	4.00e-92	330.00
IUUC-Tsy-119255	Tarsius syrichta	95.05	6.00e-171	592.00
IUUC-Tni-120140	Tetraodon nigroviridis	61.37	5.00e-88	317.00
IUUC-Tae-124420	Triticum aestivum	30.39	5.00e-17	82.40
IUUC-Tbe-127306	Tupaia belangeri	94.06	7.00e-169	585.00
IUUC-Ttr-128923	Tursiops truncatus	93.42	4.00e-155	540.00
IUUC-Vpa-130148	Vicugna pacos	93.73	2.00e-168	584.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence