iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059953

UUCD1 version

UUC-MeG-00365

Ensembl Protein ID

ENSMGAP00000007863.1

UniProt Accession

G1N6V2; G1N6V2_MELGA

Protein Name

Uncharacterized protein

Gene Name

KLHL22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000007698.1	ENSMGAT00000008646.1	ENSMGAP00000007863.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	9.00e-19	67.4	51	115
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.90e-07	29.4	150	179

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lvv+++ ++ah+i Laas+++F+ +f ++l+e++ +++v+i+++++ ++  +l+F+Yt++l++
   Q: 51   DVVLVVEEKPIEAHRILLAASCDYFRGMFAGGLREME-QEEVHIHGISYNAMCKILNFIYTSELEL 115
           9***********************************8.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
           eN l+++ +Ad+yd+++L d+ +++ilk+F
   Q: 150  ENILDVYKLADHYDLRHLSDQLDSYILKNF 179
           8****************************9 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MAEDQELTQP HKAQLESSLQ QRTSNTYRSA EHSQALLSGL VSLRDSSILF DVVLVVEEKP 60
IEAHRILLAA SCDYFRGMFA GGLREMEQEE VHIHGISYNA MCKILNFIYT SELELSVNSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCACAGATT TCATTCTGCT GCAGCTTTTG GCTGAGCATT TCTGCCTGGG ATGGCGGAGG 60
ATCAGGAGCT GACTCAGCCA CACAAAGCTC AACTCGAGTC CTCCCTTCAG CAGCGCACCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005813--C:centrosome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:0005827--C:polar microtubule
GO:0051301--P:cell division
GO:0000070--P:mitotic sister chromatid segregation
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002097	Ailuropoda melanoleuca	77.12	0.00e+00	1017.00
IUUC-Apl-004081	Anas platyrhynchos	99.53	0.00e+00	1330.00
IUUC-Aca-005015	Anolis carolinensis	65.34	0.00e+00	866.00
IUUC-Ame-011712	Astyanax mexicanus	58.44	0.00e+00	761.00
IUUC-Bta-012594	Bos taurus	76.33	0.00e+00	1022.00
IUUC-Cja-019752	Callithrix jacchus	78.39	0.00e+00	851.00
IUUC-Cfa-020884	Canis familiaris	77.27	0.00e+00	1038.00
IUUC-Cpo-021711	Cavia porcellus	77.43	0.00e+00	1036.00
IUUC-Csa-023211	Chlorocebus sabaeus	78.06	0.00e+00	1045.00
IUUC-Dre-028395	Danio rerio	60.61	0.00e+00	785.00
IUUC-Dno-030096	Dasypus novemcinctus	77.43	0.00e+00	1050.00
IUUC-Dor-030709	Dipodomys ordii	77.03	5.00e-170	590.00
IUUC-Eca-033388	Equus caballus	77.12	0.00e+00	1039.00
IUUC-Eeu-034616	Erinaceus europaeus	69.28	0.00e+00	911.00
IUUC-Fca-035815	Felis catus	77.43	0.00e+00	1040.00
IUUC-Fal-037311	Ficedula albicollis	96.75	0.00e+00	1228.00
IUUC-Gmo-039571	Gadus morhua	53.90	8.00e-166	576.00
IUUC-Gga-040992	Gallus gallus	100.00	0.00e+00	1334.00
IUUC-Gac-042041	Gasterosteus aculeatus	59.08	0.00e+00	714.00
IUUC-Ggo-045141	Gorilla gorilla	73.67	0.00e+00	986.00
IUUC-Hsa-045984	Homo sapiens	78.06	0.00e+00	1046.00
IUUC-Itr-048890	Ictidomys tridecemlineatus	77.27	0.00e+00	1040.00
IUUC-Lch-049700	Latimeria chalumnae	63.18	0.00e+00	785.00
IUUC-Loc-052141	Lepisosteus oculatus	64.26	0.00e+00	857.00
IUUC-Laf-053487	Loxodonta africana	79.06	0.00e+00	1038.00
IUUC-Mcc-054682	Macaca mulatta	79.77	0.00e+00	860.00
IUUC-Meu-055937	Macropus eugenii	71.79	0.00e+00	943.00
IUUC-Mmr-061743	Microcebus murinus	77.59	0.00e+00	1036.00
IUUC-Mdo-062328	Monodelphis domestica	79.00	0.00e+00	1048.00
IUUC-Mmu-063979	Mus musculus	76.86	0.00e+00	1020.00
IUUC-Mpu-066750	Mustela putorius furo	77.43	0.00e+00	1040.00
IUUC-Mlu-066960	Myotis lucifugus	77.59	0.00e+00	1041.00
IUUC-Nle-069690	Nomascus leucogenys	79.14	0.00e+00	947.00
IUUC-Opr-071059	Ochotona princeps	71.83	0.00e+00	953.00
IUUC-Ont-072004	Oreochromis niloticus	60.21	0.00e+00	726.00
IUUC-Oan-073172	Ornithorhynchus anatinus	64.07	0.00e+00	772.00
IUUC-Ocu-074310	Oryctolagus cuniculus	75.00	2.00e-123	434.00
IUUC-Ola-086599	Oryzias latipes	57.61	0.00e+00	721.00
IUUC-Oga-087980	Otolemur garnettii	76.96	0.00e+00	1035.00
IUUC-Oar-089956	Ovis aries	64.40	0.00e+00	753.00
IUUC-Ptr-090598	Pan troglodytes	79.22	0.00e+00	951.00
IUUC-Pan-092387	Papio anubis	79.96	0.00e+00	863.00
IUUC-Psi-093484	Pelodiscus sinensis	85.42	0.00e+00	1148.00
IUUC-Pma-094224	Petromyzon marinus	51.59	3.00e-180	624.00
IUUC-Pfo-096149	Poecilia formosa	60.20	0.00e+00	743.00
IUUC-Pab-098097	Pongo abelii	77.90	0.00e+00	1045.00
IUUC-Pca-100118	Procavia capensis	79.19	2.00e-175	608.00
IUUC-Pva-103174	Pteropus vampyrus	74.91	2.00e-123	436.00
IUUC-Rno-105350	Rattus norvegicus	77.87	0.00e+00	999.00
IUUC-Sha-106817	Sarcophilus harrisii	79.03	1.00e-130	459.00
IUUC-Sar-113490	Sorex araneus	79.88	8.00e-163	566.00
IUUC-Ssc-115827	Sus scrofa	76.96	0.00e+00	1031.00
IUUC-Tgu-116748	Taeniopygia guttata	97.34	0.00e+00	1081.00
IUUC-Tru-118644	Takifugu rubripes	57.12	0.00e+00	735.00
IUUC-Tsy-118888	Tarsius syrichta	73.31	0.00e+00	862.00
IUUC-Tni-120060	Tetraodon nigroviridis	54.26	4.00e-180	624.00
IUUC-Ttr-129183	Tursiops truncatus	77.94	0.00e+00	937.00
IUUC-Xtr-132780	Xenopus tropicalis	71.32	0.00e+00	947.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence