iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065791

Ensembl Protein ID

ENSMPUP00000014943.1

UniProt Accession

M3YUD3; M3YUD3_MUSPF

Genbank Protein ID

ENSMPUP00000014943

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01001438

Gene Name

SKP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000015054.1	ENSMPUT00000015180.1	ENSMPUP00000014943.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	28.40	1.00e-31	134.00	IUUC-Cel-018410
E3 adaptor/Cullin RING/SCF/F-box	91.28	0.00e+00	816.00	IUUC-Hsa-046512

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MHAFKTPEPV DAMHRKHLQE IPDQSSNVTT SFTWGWDSSK TSELLSGMGV SALEKEEVDS 60
ENIPQELLSN LAHPQSPPRK RLKSKGNEKD FVIVRRPKLN RDSFPGVSWD SLPDELLLGI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCACGCAT TTAAAACTCC AGAACCTGTG GACGCCATGC ACAGGTAACC CGATTGCAAA 60
AGGGGGCGGC GAGTGAGTGA ACCATCTCAA TTCTTTTAGG CCGCGAACAT TGCTGCTTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0033148--P:positive regulation of intracellular estrogen receptor signaling pathway
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0051726--P:regulation of cell cycle
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002197	Ailuropoda melanoleuca	97.88	0.00e+00	821.00
IUUC-Atr-002711	Amborella trichopoda	25.00	2.00e-10	61.60
IUUC-Apl-003453	Anas platyrhynchos	68.18	2.00e-119	422.00
IUUC-Aca-005185	Anolis carolinensis	63.15	2.00e-144	505.00
IUUC-Ame-010665	Astyanax mexicanus	46.06	7.00e-93	334.00
IUUC-Bta-013450	Bos taurus	93.40	0.00e+00	823.00
IUUC-Bra-016626	Brassica rapa	23.53	1.00e-11	65.10
IUUC-Cel-018410	Caenorhabditis elegans	27.47	3.00e-29	122.00
IUUC-Cja-019834	Callithrix jacchus	91.04	0.00e+00	797.00
IUUC-Cfa-020401	Canis familiaris	98.17	0.00e+00	876.00
IUUC-Cpo-022183	Cavia porcellus	90.57	0.00e+00	796.00
IUUC-Csa-023418	Chlorocebus sabaeus	92.22	0.00e+00	802.00
IUUC-Cho-024412	Choloepus hoffmanni	89.83	0.00e+00	639.00
IUUC-Cin-025248	Ciona intestinalis	31.10	7.00e-41	161.00
IUUC-Csv-026189	Ciona savignyi	34.24	7.00e-37	148.00
IUUC-Cme-027297	Cyanidioschyzon merolae	36.36	6.00e-06	45.40
IUUC-Dre-028032	Danio rerio	48.27	2.00e-106	379.00
IUUC-Dno-029222	Dasypus novemcinctus	91.74	0.00e+00	821.00
IUUC-Dor-030505	Dipodomys ordii	86.44	3.00e-175	607.00
IUUC-Dme-031972	Drosophila melanogaster	32.88	2.00e-52	200.00
IUUC-Ete-032234	Echinops telfairi	84.81	5.00e-119	421.00
IUUC-Eca-033944	Equus caballus	97.02	0.00e+00	867.00
IUUC-Eeu-035008	Erinaceus europaeus	85.00	4.00e-122	430.00
IUUC-Fca-035412	Felis catus	96.46	0.00e+00	840.00
IUUC-Fal-037337	Ficedula albicollis	63.74	5.00e-141	494.00
IUUC-Gmo-038934	Gadus morhua	44.09	4.00e-42	165.00
IUUC-Gga-041152	Gallus gallus	66.90	3.00e-160	558.00
IUUC-Gac-041819	Gasterosteus aculeatus	45.57	4.00e-80	291.00
IUUC-Ggo-045479	Gorilla gorilla	91.24	0.00e+00	665.00
IUUC-Hsa-046512	Homo sapiens	91.28	0.00e+00	816.00
IUUC-Itr-048515	Ictidomys tridecemlineatus	92.63	0.00e+00	771.00
IUUC-Lch-050115	Latimeria chalumnae	59.19	8.00e-140	489.00
IUUC-Loc-052554	Lepisosteus oculatus	50.23	6.00e-109	387.00
IUUC-Laf-053563	Loxodonta africana	91.47	0.00e+00	756.00
IUUC-Mcc-055143	Macaca mulatta	92.18	0.00e+00	797.00
IUUC-Meu-056593	Macropus eugenii	57.49	4.00e-107	381.00
IUUC-Mga-060084	Meleagris gallopavo	59.39	1.00e-84	305.00
IUUC-Mmr-060660	Microcebus murinus	95.18	0.00e+00	852.00
IUUC-Mdo-062363	Monodelphis domestica	69.81	1.00e-161	562.00
IUUC-Mmu-063287	Mus musculus	85.14	0.00e+00	754.00
IUUC-Mlu-067714	Myotis lucifugus	90.82	0.00e+00	777.00
IUUC-Nle-069823	Nomascus leucogenys	92.45	0.00e+00	805.00
IUUC-Opr-071046	Ochotona princeps	75.00	3.00e-108	385.00
IUUC-Ont-071820	Oreochromis niloticus	46.88	2.00e-70	259.00
IUUC-Ocu-074868	Oryctolagus cuniculus	93.16	0.00e+00	813.00
IUUC-Ola-086608	Oryzias latipes	47.00	7.00e-78	284.00
IUUC-Oga-089044	Otolemur garnettii	94.34	0.00e+00	823.00
IUUC-Oar-089650	Ovis aries	93.35	0.00e+00	843.00
IUUC-Ptr-090743	Pan troglodytes	91.98	0.00e+00	802.00
IUUC-Pan-092501	Papio anubis	92.22	0.00e+00	803.00
IUUC-Psi-094032	Pelodiscus sinensis	67.30	6.00e-164	570.00
IUUC-Pfo-097279	Poecilia formosa	46.53	2.00e-65	243.00
IUUC-Pab-097821	Pongo abelii	92.09	0.00e+00	669.00
IUUC-Pca-100100	Procavia capensis	90.96	1.00e-180	625.00
IUUC-Pva-103181	Pteropus vampyrus	94.35	0.00e+00	662.00
IUUC-Rno-105091	Rattus norvegicus	86.97	0.00e+00	761.00
IUUC-Sha-107226	Sarcophilus harrisii	72.04	4.00e-171	593.00
IUUC-Ssc-115665	Sus scrofa	96.46	0.00e+00	839.00
IUUC-Tgu-116982	Taeniopygia guttata	63.59	2.00e-138	485.00
IUUC-Tru-118276	Takifugu rubripes	47.29	3.00e-76	278.00
IUUC-Tsy-119074	Tarsius syrichta	92.66	0.00e+00	675.00
IUUC-Tni-120702	Tetraodon nigroviridis	47.55	2.00e-51	196.00
IUUC-Tbe-127990	Tupaia belangeri	93.29	8.00e-163	566.00
IUUC-Ttr-128661	Tursiops truncatus	82.31	2.00e-120	425.00
IUUC-Vvi-131526	Vitis vinifera	25.77	5.00e-10	60.10
IUUC-Xtr-132166	Xenopus tropicalis	57.04	1.00e-128	452.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence