iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034253

UUCD1 version

UUC-EqC-01030

Ensembl Protein ID

ENSECAP00000016530.1

UniProt Accession

F6ZE61; F6ZE61_HORSE

Protein Name

Uncharacterized protein

Gene Name

USP32

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000018702.1	ENSECAT00000020154.1	ENSECAP00000016530.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.40e-107	358.3	694	1527

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++ + ++  +ln++np ++kg+++k++ +l++elw++++k+v+p +l  +++k+a++f+g
   Q: 694  TGLSNLGNTCFMNSSIQCVSNTQPLTQYFISgRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKNVAPLKLRWTIAKYAPRFNG 780
           7******************************9******************************************************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a++++ ++n+s+++dlF+gql+sq+kc++c+++s+r++p
   Q: 781  FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSD--GRPDWevaaeAWDNHLRRNRSIVVDLFHGQLRSQVKCKTCGHISVRFDP 865
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++ +++e                                                                      
   Q: 866  FNFLSLPLPMDSYMHLEitvikldgttpvryglrlnmdekytglkkqlsdlcglkseqillaevhgsniknfpqdnqkvrlsvsgfl 952
           *************9999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 953  cafeipipgspisasspiqtdfssspstngmftlttngdlprsifipngmpntvvpcgteknftngmvnghmpslpdnpftgyiiav 1039
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1040 hrkmmrtelyflssqknrpslfgmplivpctvhtrkkdlydavwiqvsrlasplppqeasnhaqdcddsmgyqypftlrvvqkdgns 1126
           *************************************************************************************** PP
   S: 186  ...................................................................slqdcLesftkeeelegenk 205
                                                                              +l++cL++ft+eeel ++++
   Q: 1127 cawcpwyrfcrgckidcgedrafignayiavdwdptalhlryqtsqervvdehesveqsrraqaepiNLDSCLRAFTSEEELGENEM 1213
           *************************************************************************************** PP
   S: 206  yycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts........................ 267
           yyc+kck ++ a+kkl+l++lP+vLi+hLkRf+f +   + +k +k v+fp+e +d s f++                         
   Q: 1214 YYCSKCKTHCLATKKLDLWRLPPVLIIHLKRFQFVNG--RWIKSQKIVKFPREsFDPSAFLVPrdpalcqrkpltpqgddlsepkvp 1298
           ********************************99775..5569******************99999999999999999999999999 PP
   S: 268  ....................................................................................... 267
                                                                                                  
   Q: 1299 agevkkvdaqnsageedvlmskspsslsaniisspkgspsssrksgtscpssknsspnssprtlgrskgrlrlpqigsknklssske 1385
           999999999999988888888888888888888888888888888888777777777777777776666666666666666666655 PP
   S: 268  ..........peekqke.....................................................................k 275
                           +                                                                     k
   Q: 1386 nldaskengsG-----QvcelvdalsrghmlggsqpelvtpqdhevalangfvyeheacsngysngqlenhseedstddqredihvK 1467
           55555555550.....0555555555555555555555555555555556666666666666666666666666667777778888* PP
   S: 276  kkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
            +Y+L+a+ +HsG l++GHYv+y+kn + kW++++Ds+++e++ +e+ +   ++aY+lfY+++
   Q: 1468 PIYNLYAISCHSGILGGGHYVTYAKNPNSKWYCYNDSSCKELHPDEIDT---DSAYILFYEQQ 1527
           *************************************************...********985 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MGQHCFIREV LGDGVPPKVA EVIYCSFGGT SKGLHFNNLI VGLVLLTRGR DEEKAKYIFS 60
LFASESGSYV IREEMERMLH LVDGKVPDTL RKCFSEGEKV NYEKFRNWLL LNKDAFTFSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGTCGG TGGGCGGCGG CCGGGAGGAG CCCCCGGGGC AAAAGTCGCA CTTGTTAGTG 60
TGGGGGGGAG GGGGCCGGGG GACGCCGACT CCGTCACCCA GGGACGCCGA AGAGAAGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	97.37	0.00e+00	2648.00
IUUC-Apl-003272	Anas platyrhynchos	83.88	0.00e+00	2680.00
IUUC-Aca-005057	Anolis carolinensis	84.18	0.00e+00	2284.00
IUUC-Ame-010781	Astyanax mexicanus	81.36	0.00e+00	2133.00
IUUC-Bta-013502	Bos taurus	93.39	0.00e+00	2850.00
IUUC-Cja-018754	Callithrix jacchus	96.61	0.00e+00	3011.00
IUUC-Cfa-020526	Canis familiaris	97.51	0.00e+00	3047.00
IUUC-Cpo-021568	Cavia porcellus	91.41	0.00e+00	2766.00
IUUC-Csa-023143	Chlorocebus sabaeus	96.61	0.00e+00	2975.00
IUUC-Cho-024603	Choloepus hoffmanni	60.65	0.00e+00	637.00
IUUC-Cin-025583	Ciona intestinalis	50.58	0.00e+00	1228.00
IUUC-Csv-026344	Ciona savignyi	47.23	0.00e+00	1130.00
IUUC-Dre-028121	Danio rerio	76.89	0.00e+00	2322.00
IUUC-Dno-029911	Dasypus novemcinctus	95.79	0.00e+00	3017.00
IUUC-Dor-030608	Dipodomys ordii	67.56	0.00e+00	683.00
IUUC-Dme-032094	Drosophila melanogaster	44.83	7.00e-123	436.00
IUUC-Ete-032639	Echinops telfairi	94.63	0.00e+00	1596.00
IUUC-Eeu-035084	Erinaceus europaeus	84.06	0.00e+00	1575.00
IUUC-Fca-035474	Felis catus	96.88	0.00e+00	2521.00
IUUC-Fal-036985	Ficedula albicollis	84.63	0.00e+00	2638.00
IUUC-Gmo-039568	Gadus morhua	80.23	0.00e+00	2061.00
IUUC-Gga-040509	Gallus gallus	83.16	0.00e+00	2673.00
IUUC-Gac-041757	Gasterosteus aculeatus	80.41	0.00e+00	2122.00
IUUC-Ggo-044956	Gorilla gorilla	87.81	0.00e+00	1761.00
IUUC-Hsa-046107	Homo sapiens	96.68	0.00e+00	3001.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	95.17	0.00e+00	1211.00
IUUC-Lch-050681	Latimeria chalumnae	78.36	0.00e+00	2409.00
IUUC-Loc-052474	Lepisosteus oculatus	77.82	0.00e+00	2424.00
IUUC-Laf-054273	Loxodonta africana	96.42	0.00e+00	2996.00
IUUC-Mcc-054718	Macaca mulatta	96.55	0.00e+00	3003.00
IUUC-Meu-056558	Macropus eugenii	72.43	0.00e+00	1363.00
IUUC-Mga-059892	Meleagris gallopavo	84.89	0.00e+00	2669.00
IUUC-Mmr-060866	Microcebus murinus	95.56	0.00e+00	3023.00
IUUC-Mdo-062607	Monodelphis domestica	92.21	0.00e+00	2923.00
IUUC-Mmu-063797	Mus musculus	94.69	0.00e+00	3030.00
IUUC-Mpu-066121	Mustela putorius furo	98.02	0.00e+00	3078.00
IUUC-Mlu-067581	Myotis lucifugus	95.73	0.00e+00	3031.00
IUUC-Nle-069916	Nomascus leucogenys	94.19	0.00e+00	2897.00
IUUC-Opr-071073	Ochotona princeps	83.82	0.00e+00	1153.00
IUUC-Ont-071310	Oreochromis niloticus	79.85	0.00e+00	2093.00
IUUC-Oan-073356	Ornithorhynchus anatinus	90.55	0.00e+00	2864.00
IUUC-Ocu-074216	Oryctolagus cuniculus	95.97	0.00e+00	3000.00
IUUC-Ola-087434	Oryzias latipes	74.67	0.00e+00	2246.00
IUUC-Oga-089034	Otolemur garnettii	95.15	0.00e+00	2975.00
IUUC-Oar-090369	Ovis aries	97.25	0.00e+00	3093.00
IUUC-Ptr-090605	Pan troglodytes	96.74	0.00e+00	3004.00
IUUC-Pan-092381	Papio anubis	96.55	0.00e+00	2997.00
IUUC-Psi-093819	Pelodiscus sinensis	87.15	0.00e+00	2763.00
IUUC-Pma-094480	Petromyzon marinus	63.88	0.00e+00	1438.00
IUUC-Pfo-096561	Poecilia formosa	80.05	0.00e+00	2063.00
IUUC-Pab-097643	Pongo abelii	96.50	0.00e+00	2946.00
IUUC-Pca-100944	Procavia capensis	78.14	0.00e+00	1050.00
IUUC-Pva-102732	Pteropus vampyrus	87.21	0.00e+00	2640.00
IUUC-Rno-105113	Rattus norvegicus	94.88	0.00e+00	3008.00
IUUC-Sha-107608	Sarcophilus harrisii	85.42	3.00e-179	620.00
IUUC-Sar-113201	Sorex araneus	84.93	0.00e+00	1716.00
IUUC-Ssc-115469	Sus scrofa	95.12	0.00e+00	684.00
IUUC-Tgu-117322	Taeniopygia guttata	84.43	0.00e+00	2705.00
IUUC-Tru-118705	Takifugu rubripes	68.97	0.00e+00	678.00
IUUC-Tsy-119433	Tarsius syrichta	82.51	0.00e+00	1471.00
IUUC-Tni-120631	Tetraodon nigroviridis	79.45	0.00e+00	2103.00
IUUC-Tbe-127553	Tupaia belangeri	86.06	0.00e+00	693.00
IUUC-Ttr-128260	Tursiops truncatus	96.29	0.00e+00	3051.00
IUUC-Vpa-130479	Vicugna pacos	92.20	0.00e+00	2848.00
IUUC-Xtr-132686	Xenopus tropicalis	83.62	0.00e+00	2575.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence