iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036380

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02102069

Gene Name

RBCK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000003278.3	ENSFCAT00000003278.3	ENSFCAP00000003025.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	2.90e-11	42.7	195	221
ULD/UDP/UBQ/UBQ_Other	1.60e-06	27.9	60	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 3    aqWaCsaCTflNePeavkCemCsrpRg 29
            +W+C+ CTf+N+P +++CemC+r R+
   Q: 195  VGWQCPGCTFINKPTRPGCEMCCRARP 221
           68************************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 4    tvksldgseltlk..vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglk 62
            v++++  + t++  v p++tVa LK++++   g+pp  q++++ G+ L +d  tL ++g++
   Q: 60   SVEDAQMHTVTIWltVRPDMTVASLKDMVFLDYGFPPVLQQWVI-GQRLaRDQETLHSHGVR 120
           5666665577777889****************************.55555*********996 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MDEKTKKAEE MALRLTRAVA GGDEHVAVQC AIWLAEQRVP LSVQLKPEVS PTQDIRLWVS 60
VEDAQMHTVT IWLTVRPDMT VASLKDMVFL DYGFPPVLQQ WVIGQRLARD QETLHSHGVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCAGACCC GCCCCCCGCC CCTTCCCGTG GCGGTGCGGG CGCGGCCTGC CGGGTGAGTG 60
AAGGTCGGGG AGTCCCGGAT CAGCCCAACA GGGGTCACCC CGGTCAAGGT CTTTGAGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR002867--IBR_dom
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR027370--Znf-RING_LisH
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50053--UBIQUITIN_2
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00547--ZnF_RBZ

Gene Ontology

GO:0071797--C:LUBAC complex
GO:0043130--F:ubiquitin binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060546--P:negative regulation of necroptotic process
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0042346--P:positive regulation of NF-kappaB import into nucleus
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination
GO:0050852--P:T cell receptor signaling pathway

KEGG

fca:101083505

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001540	Ailuropoda melanoleuca	95.69	0.00e+00	892.00
IUUC-Apl-003627	Anas platyrhynchos	60.81	3.00e-19	85.50
IUUC-Aca-004507	Anolis carolinensis	64.10	2.00e-151	528.00
IUUC-Ame-011008	Astyanax mexicanus	52.56	3.00e-141	494.00
IUUC-Bta-013247	Bos taurus	94.12	0.00e+00	887.00
IUUC-Bci-013637	Botrytis cinerea	25.37	6.00e-13	69.70
IUUC-Cja-018880	Callithrix jacchus	93.73	0.00e+00	882.00
IUUC-Cfa-020477	Canis familiaris	97.45	0.00e+00	915.00
IUUC-Cpo-021558	Cavia porcellus	89.80	0.00e+00	837.00
IUUC-Csa-024129	Chlorocebus sabaeus	94.12	0.00e+00	849.00
IUUC-Cin-025630	Ciona intestinalis	38.34	3.00e-81	295.00
IUUC-Csv-026069	Ciona savignyi	50.80	6.00e-72	263.00
IUUC-Dre-027591	Danio rerio	51.56	3.00e-138	485.00
IUUC-Dno-029015	Dasypus novemcinctus	91.37	0.00e+00	847.00
IUUC-Dor-030313	Dipodomys ordii	81.87	0.00e+00	736.00
IUUC-Ete-032908	Echinops telfairi	81.60	0.00e+00	746.00
IUUC-Eca-034295	Equus caballus	77.34	0.00e+00	718.00
IUUC-Eeu-034454	Erinaceus europaeus	85.76	4.00e-115	407.00
IUUC-Fal-037440	Ficedula albicollis	58.82	3.00e-14	69.30
IUUC-Gmo-038561	Gadus morhua	53.85	7.00e-118	417.00
IUUC-Gac-041319	Gasterosteus aculeatus	52.25	1.00e-136	479.00
IUUC-Ggo-044456	Gorilla gorilla	65.00	7.00e-146	510.00
IUUC-Hsa-045738	Homo sapiens	95.29	0.00e+00	849.00
IUUC-Itr-049042	Ictidomys tridecemlineatus	92.55	0.00e+00	845.00
IUUC-Lch-050269	Latimeria chalumnae	44.28	2.00e-112	400.00
IUUC-Loc-052776	Lepisosteus oculatus	50.18	6.00e-138	484.00
IUUC-Laf-054269	Loxodonta africana	91.76	0.00e+00	865.00
IUUC-Mcc-055669	Macaca mulatta	94.90	0.00e+00	863.00
IUUC-Mga-059615	Meleagris gallopavo	56.25	3.00e-17	79.30
IUUC-Mmr-061562	Microcebus murinus	92.49	0.00e+00	766.00
IUUC-Mdo-062263	Monodelphis domestica	78.29	0.00e+00	741.00
IUUC-Mmu-064325	Mus musculus	90.39	0.00e+00	817.00
IUUC-Mpu-066385	Mustela putorius furo	97.25	0.00e+00	918.00
IUUC-Mlu-067000	Myotis lucifugus	91.76	0.00e+00	846.00
IUUC-Nle-069812	Nomascus leucogenys	94.71	0.00e+00	856.00
IUUC-Opr-070575	Ochotona princeps	95.59	1.00e-107	383.00
IUUC-Ont-072405	Oreochromis niloticus	50.30	1.00e-132	466.00
IUUC-Ocu-074358	Oryctolagus cuniculus	81.57	0.00e+00	765.00
IUUC-Ola-086403	Oryzias latipes	52.80	2.00e-137	482.00
IUUC-Oga-087986	Otolemur garnettii	92.75	0.00e+00	830.00
IUUC-Oar-089600	Ovis aries	91.76	0.00e+00	881.00
IUUC-Ptr-091224	Pan troglodytes	95.10	0.00e+00	848.00
IUUC-Pan-092739	Papio anubis	95.10	0.00e+00	866.00
IUUC-Pma-094407	Petromyzon marinus	47.46	3.00e-125	441.00
IUUC-Pfo-097161	Poecilia formosa	51.67	6.00e-132	464.00
IUUC-Pab-098627	Pongo abelii	95.10	0.00e+00	842.00
IUUC-Pca-100641	Procavia capensis	93.08	0.00e+00	814.00
IUUC-Pva-102670	Pteropus vampyrus	93.92	0.00e+00	890.00
IUUC-Pte-104234	Pyrenophora teres	25.41	9.00e-12	64.70
IUUC-Rno-105504	Rattus norvegicus	90.00	0.00e+00	811.00
IUUC-Sha-107342	Sarcophilus harrisii	77.52	0.00e+00	761.00
IUUC-Sar-113425	Sorex araneus	89.04	8.00e-114	403.00
IUUC-Ssc-115904	Sus scrofa	94.22	1.00e-90	324.00
IUUC-Tru-118096	Takifugu rubripes	51.73	3.00e-139	488.00
IUUC-Tni-119873	Tetraodon nigroviridis	49.12	8.00e-136	476.00
IUUC-Tbe-127578	Tupaia belangeri	91.73	0.00e+00	696.00
IUUC-Ttr-129107	Tursiops truncatus	94.51	0.00e+00	847.00
IUUC-Vpa-130353	Vicugna pacos	95.55	1.00e-118	419.00
IUUC-Xtr-132168	Xenopus tropicalis	42.50	2.00e-93	336.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence