iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033986

Ensembl Protein ID

ENSECAP00000005173.1

UniProt Accession

F7DA04; F7DA04_HORSE

Protein Name

Uncharacterized protein

Gene Name

NACC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000006963.1	ENSECAT00000007147.1	ENSECAP00000005173.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	7.40e-16	58.4	30	92

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgklde 67
           +Dv +vv+g+ f+ah++vLaasS +F++lf+++     sk+  e+ + v p +f+++l+F+Ytg+l++
   Q: 30   CDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGN-----SKSAFELPGtVPPACFQQILSFCYTGRLTM 92
           8*****************************774.....46778***88*****************986 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MSQMLHIEIP NFGNTVLGCL NEQRLLGLYC DVSIVVKGQA FKAHRAVLAA SSLYFRDLFS 60
GNSKSAFELP GTVPPACFQQ ILSFCYTGRL TMAASEQLVV MYTAGFLQIQ HIVERGTDLM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGCCTGCC CACTTGCGCC CGCCCGCCAT GTCGCAGATG CTGCACATAG AGATTCCCAA 60
CTTCGGGAAC ACCGTGCTCG GCTGCCTCAA CGAGCAGCGC CTGCTGGGCC TCTACTGCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR018379--BEN_domain
IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ

PROSITE

PS51457--BEN
PS50097--BTB

Pfam

PF10523--BEN
PF00651--BTB

SMART

SM01025--BEN
SM00225--BTB

Gene Ontology

GO:0005739--C:mitochondrion
GO:0000790--C:nuclear chromatin
GO:0005730--C:nucleolus
GO:0016581--C:NuRD complex
GO:0004407--F:histone deacetylase activity
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001076--F:transcription factor activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0034629--P:cellular protein complex localization
GO:0008285--P:negative regulation of cell proliferation
GO:1900477--P:negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010608--P:posttranscriptional regulation of gene expression
GO:0051260--P:protein homooligomerization

KEGG

ecb:100066292

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001902	Ailuropoda melanoleuca	93.28	0.00e+00	833.00
IUUC-Apl-004203	Anas platyrhynchos	81.77	0.00e+00	954.00
IUUC-Ame-011046	Astyanax mexicanus	56.60	4.00e-149	521.00
IUUC-Bta-012908	Bos taurus	95.73	0.00e+00	975.00
IUUC-Cja-019140	Callithrix jacchus	93.38	0.00e+00	1038.00
IUUC-Cfa-020493	Canis familiaris	94.48	1.00e-172	599.00
IUUC-Cpo-022399	Cavia porcellus	92.20	0.00e+00	1058.00
IUUC-Csa-024135	Chlorocebus sabaeus	93.20	0.00e+00	1025.00
IUUC-Dre-027761	Danio rerio	70.91	2.00e-81	296.00
IUUC-Dno-029271	Dasypus novemcinctus	78.81	0.00e+00	760.00
IUUC-Ete-032427	Echinops telfairi	88.46	0.00e+00	915.00
IUUC-Eeu-035211	Erinaceus europaeus	91.82	0.00e+00	1017.00
IUUC-Fca-035733	Felis catus	94.38	0.00e+00	910.00
IUUC-Fal-037348	Ficedula albicollis	83.19	0.00e+00	952.00
IUUC-Gmo-039529	Gadus morhua	82.44	1.00e-94	340.00
IUUC-Gga-040405	Gallus gallus	84.67	0.00e+00	987.00
IUUC-Gac-041308	Gasterosteus aculeatus	67.74	2.00e-172	598.00
IUUC-Ggo-044687	Gorilla gorilla	75.18	0.00e+00	769.00
IUUC-Hsa-045955	Homo sapiens	95.65	0.00e+00	1003.00
IUUC-Itr-048872	Ictidomys tridecemlineatus	92.88	0.00e+00	1013.00
IUUC-Lch-049615	Latimeria chalumnae	75.72	0.00e+00	899.00
IUUC-Loc-051881	Lepisosteus oculatus	69.62	0.00e+00	683.00
IUUC-Lma-053325	Leptosphaeria maculans	35.09	2.00e-06	45.80
IUUC-Laf-054170	Loxodonta africana	89.23	0.00e+00	976.00
IUUC-Mga-059627	Meleagris gallopavo	83.99	0.00e+00	981.00
IUUC-Mdo-063014	Monodelphis domestica	88.57	2.00e-178	618.00
IUUC-Mmu-063897	Mus musculus	91.68	0.00e+00	1059.00
IUUC-Mpu-066806	Mustela putorius furo	94.21	0.00e+00	942.00
IUUC-Nle-069114	Nomascus leucogenys	91.34	0.00e+00	922.00
IUUC-Opr-071127	Ochotona princeps	94.57	2.00e-71	263.00
IUUC-Ont-071693	Oreochromis niloticus	79.65	5.00e-106	377.00
IUUC-Oan-073510	Ornithorhynchus anatinus	87.29	0.00e+00	1015.00
IUUC-Ola-086572	Oryzias latipes	64.72	0.00e+00	633.00
IUUC-Oga-088653	Otolemur garnettii	89.61	0.00e+00	1024.00
IUUC-Oar-089811	Ovis aries	91.93	0.00e+00	811.00
IUUC-Ptr-090703	Pan troglodytes	93.84	0.00e+00	989.00
IUUC-Pan-092388	Papio anubis	92.06	0.00e+00	1031.00
IUUC-Psi-093786	Pelodiscus sinensis	84.67	0.00e+00	993.00
IUUC-Pma-094566	Petromyzon marinus	70.37	1.00e-64	240.00
IUUC-Pno-095029	Phaeosphaeria nodorum	27.85	3.00e-05	41.60
IUUC-Pfo-096554	Poecilia formosa	62.72	5.00e-179	620.00
IUUC-Pca-101090	Procavia capensis	90.71	0.00e+00	980.00
IUUC-Pva-102843	Pteropus vampyrus	92.15	0.00e+00	1001.00
IUUC-Rno-105139	Rattus norvegicus	90.66	0.00e+00	1060.00
IUUC-Sha-107545	Sarcophilus harrisii	87.41	0.00e+00	1005.00
IUUC-Tgu-117401	Taeniopygia guttata	84.50	0.00e+00	968.00
IUUC-Tru-118080	Takifugu rubripes	68.12	2.00e-167	582.00
IUUC-Tni-120321	Tetraodon nigroviridis	64.83	1.00e-169	589.00
IUUC-Ttr-128369	Tursiops truncatus	92.60	0.00e+00	724.00
IUUC-Xtr-131793	Xenopus tropicalis	79.77	6.00e-156	543.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence