iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062776

UUCD1 version

UUC-MoD-01008

Ensembl Protein ID

ENSMODP00000009317.3

UniProt Accession

F7GK24; F7GK24_MONDO

Protein Name

Uncharacterized protein

Gene Name

KLHL28

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000007505.3	ENSMODT00000009498.3	ENSMODP00000009317.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.30e-18	66.0	60	123
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.50e-13	47.7	159	190

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +D+il vg+++++ahk+vLa+ S++F+a+f+++l+e++ +++ve++ ++  +++a++++ Ytg++
   Q: 60   CDIILRVGDVKIHAHKVVLASISPYFKAMFTGNLSEKE-NNEVEFQCIDEAALQAIVEYAYTGTV 123
           8***********************************97.************************87 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nc+gi rfA++y+c+dL++aa+++i+++F+
   Q: 159  PGNCIGISRFAETYGCHDLYLAANKYICQNFE 190
           56*****************************5 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MPLDRSPQTS EHHLYRTRRE LHWTEMDQTP PTYMLANLTL LHSEQLLQGL NLLRQHHELC 60
DIILRVGDVK IHAHKVVLAS ISPYFKAMFT GNLSEKENNE VEFQCIDEAA LQAIVEYAYT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAATTCTCC CAAAAGAGTG AAATATATGA AGGGCAATGC CTTTGGATAG AAGCCCACAG 60
ACTTCTGAGC ATGTAAGTTC AGCCCACCTA CAAGCTACGT ACCATAGAGG AAGTCTTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030569--KLHL28
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001581	Ailuropoda melanoleuca	93.36	0.00e+00	1131.00
IUUC-Apl-003577	Anas platyrhynchos	94.41	0.00e+00	1109.00
IUUC-Aca-004320	Anolis carolinensis	89.44	0.00e+00	956.00
IUUC-Ame-011433	Astyanax mexicanus	86.51	0.00e+00	1013.00
IUUC-Bta-012650	Bos taurus	93.35	0.00e+00	1126.00
IUUC-Cja-019878	Callithrix jacchus	92.13	0.00e+00	1125.00
IUUC-Cfa-020936	Canis familiaris	92.99	0.00e+00	1125.00
IUUC-Cpo-022212	Cavia porcellus	92.12	0.00e+00	1116.00
IUUC-Csa-023372	Chlorocebus sabaeus	92.64	0.00e+00	1124.00
IUUC-Cho-024885	Choloepus hoffmanni	93.31	7.00e-165	573.00
IUUC-Dno-029895	Dasypus novemcinctus	91.77	0.00e+00	1114.00
IUUC-Ete-032703	Echinops telfairi	91.28	0.00e+00	864.00
IUUC-Eca-034150	Equus caballus	93.17	0.00e+00	1123.00
IUUC-Eeu-035233	Erinaceus europaeus	90.89	0.00e+00	1102.00
IUUC-Fca-036445	Felis catus	92.82	0.00e+00	1121.00
IUUC-Fal-037156	Ficedula albicollis	83.36	0.00e+00	1012.00
IUUC-Gmo-039158	Gadus morhua	86.51	0.00e+00	1040.00
IUUC-Gga-040855	Gallus gallus	94.05	0.00e+00	1136.00
IUUC-Gac-041294	Gasterosteus aculeatus	85.11	0.00e+00	1026.00
IUUC-Ggo-045399	Gorilla gorilla	92.66	0.00e+00	1124.00
IUUC-Hsa-046199	Homo sapiens	92.66	0.00e+00	1124.00
IUUC-Itr-048859	Ictidomys tridecemlineatus	92.29	0.00e+00	1117.00
IUUC-Lch-049445	Latimeria chalumnae	92.17	0.00e+00	843.00
IUUC-Loc-052737	Lepisosteus oculatus	88.27	0.00e+00	1042.00
IUUC-Laf-054173	Loxodonta africana	92.13	0.00e+00	1113.00
IUUC-Mcc-055000	Macaca mulatta	92.66	0.00e+00	1125.00
IUUC-Meu-056028	Macropus eugenii	91.00	9.00e-153	533.00
IUUC-Mga-059609	Meleagris gallopavo	93.55	0.00e+00	1134.00
IUUC-Mmr-060842	Microcebus murinus	92.33	0.00e+00	1123.00
IUUC-Mmu-063720	Mus musculus	91.94	0.00e+00	1117.00
IUUC-Mpu-066594	Mustela putorius furo	81.56	1.00e-157	549.00
IUUC-Mlu-067403	Myotis lucifugus	91.42	0.00e+00	1103.00
IUUC-Nle-069242	Nomascus leucogenys	92.29	0.00e+00	1118.00
IUUC-Opr-070942	Ochotona princeps	93.05	1.00e-167	582.00
IUUC-Ont-072586	Oreochromis niloticus	86.04	0.00e+00	1038.00
IUUC-Oan-073070	Ornithorhynchus anatinus	95.61	0.00e+00	1110.00
IUUC-Ocu-074536	Oryctolagus cuniculus	92.31	0.00e+00	1118.00
IUUC-Ola-086669	Oryzias latipes	71.16	0.00e+00	822.00
IUUC-Oga-088974	Otolemur garnettii	92.47	0.00e+00	1120.00
IUUC-Oar-089544	Ovis aries	93.19	0.00e+00	1130.00
IUUC-Ptr-091478	Pan troglodytes	92.31	0.00e+00	1116.00
IUUC-Pan-092653	Papio anubis	92.82	0.00e+00	1125.00
IUUC-Psi-094014	Pelodiscus sinensis	95.27	0.00e+00	1151.00
IUUC-Pfo-097316	Poecilia formosa	85.66	0.00e+00	1030.00
IUUC-Pab-098609	Pongo abelii	92.48	0.00e+00	1122.00
IUUC-Pva-102527	Pteropus vampyrus	94.00	1.00e-167	582.00
IUUC-Rno-105188	Rattus norvegicus	92.29	0.00e+00	1120.00
IUUC-Sha-106543	Sarcophilus harrisii	99.30	0.00e+00	1158.00
IUUC-Sar-113507	Sorex araneus	90.89	0.00e+00	1106.00
IUUC-Ssc-115803	Sus scrofa	92.64	0.00e+00	1120.00
IUUC-Tgu-116661	Taeniopygia guttata	83.43	0.00e+00	931.00
IUUC-Tru-118738	Takifugu rubripes	82.81	0.00e+00	1000.00
IUUC-Tsy-119570	Tarsius syrichta	85.31	0.00e+00	1015.00
IUUC-Tni-120041	Tetraodon nigroviridis	83.94	0.00e+00	1020.00
IUUC-Tre-122227	Trichoderma reesei	32.50	1.00e-06	46.20
IUUC-Tbe-127655	Tupaia belangeri	85.31	0.00e+00	998.00
IUUC-Ttr-129249	Tursiops truncatus	93.35	0.00e+00	1126.00
IUUC-Vpa-130034	Vicugna pacos	92.47	0.00e+00	1120.00
IUUC-Xtr-132964	Xenopus tropicalis	89.67	0.00e+00	1088.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence