iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004844

Ensembl Protein ID

ENSACAP00000008399.2

UniProt Accession

H9GE23; H9GE23_ANOCA

Protein Name

Uncharacterized protein

Gene Name

ARHGEF38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000008587.2	ENSACAT00000008581.2	ENSACAP00000008399.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.90e-11	43.7	697	755

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlvi..ekeeqdegWlkgvkelegkrGlfPenFvek 61
           k+++ + + ++a ++ eL+l++   v+++  ++ + +++W+ +  e++g++G +P+n+  k
   Q: 697  KQTFYAVHAFQARSQQELSLQEYQRVRILrfSDLSGNKEWWLA--EAKGQKGYVPANYLGK 755
           678899***********************************99..9************865 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

NMLLSCWEDS LMSPRPIGSP LENEEELNRR MMARRQKIIA EMVQTERDYL NDLELCIRIV 60
VEPLRKKQIT RFDVDGLFSN IKSLHQISTK LLSLLEEATT LTGQVFVQIK DLIEEAYKVY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACATGTTAC TATCCTGCTG GGAAGATTCT CTTATGTCCC CACATGGGAA GCTAGGTTTG 60
ACAGACAGGA GCTCACCCTG TCTTGCAGAT TCAAACCTTC AACCTTCAGG TCAATAGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR001452--SH3_domain

PROSITE

PS50010--DH_2
PS50002--SH3

Pfam

PF00621--RhoGEF
PF14604--SH3_9

SMART

SM00721--BAR
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043547--P:positive regulation of GTPase activity
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003698	Anas platyrhynchos	61.72	0.00e+00	679.00
IUUC-Gga-040892	Gallus gallus	58.92	0.00e+00	657.00
IUUC-Mga-060170	Meleagris gallopavo	62.22	4.00e-148	517.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence