iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115441

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEMK01080538

Gene Name

HECTD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000020912.1	ENSSSCT00000031754.1	ENSSSCP00000023610.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	7.80e-103	344.6	439	777

Active Site

Position(s)	Description	Evidence
745	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+v+fvgE+gld+gG+t+e++ ll++++++pd+g+f+y++++ ++++ + +      ++ + F+++G+l+g+a++++  ld+
   Q: 439  RADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSYCHWFSSFKC-----DNYSEFRLVGILMGLAVYNSITLDI 522
           589*************************************************9977765.....789********************** PP
   S: 91   plsksfyklllgk..............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           ++++++yk+ll+               +++ +dl +++pel++ l e++++ e ++ee  +  tf+v +e++g +k+++LkpgG++ipV
   Q: 523  RFPPCCYKKLLSPpivpsdqntpvgicSVTTDDLCQIMPELAHGLSELLSY-EGNVEED-FYSTFQVFQEEFGIIKSYNLKPGGDKIPV 609
           ************9666666666665555**********************9.6788885.***************************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevle 254
           tn+N++eYv+l++++ l+++i +q++af+ Gf++v+  + l l+++ee+e+l+cG++e+d+++l++ t+y+g y +++ +i++Fw+v+ 
   Q: 610  TNQNRKEYVHLYIDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVEILVCGSPELDMHALQRSTQYDG-YAKTDLTIRYFWDVVL 697
           **********************************************************************76.**************** PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +f  + +k++L+F+Tgs+r+P+gG+a+l+   f i+k ++s+++lP ++TCfn+L+LP+Y+sk+ lk+kL++ i++++gF+l+
   Q: 698  GFPLDLQKKLLHFTTGSDRVPVGGMADLN---FKISKnETSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE 777
           *****************************...9999967777**************************************985 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MSEADRVPSP AAPPAVVAAA PEEKKGKEPE REKLPPIVSA GAGAAAGLDR GSKGQISTFS 60
SFISTVNQKK EATENRSSPT HLVFPNIKNV RDLPPICLDV RQKQRVSVDA LSSEMKAPVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTGAGG CGGATCGGGT GCCCTCGCCT GCCGCGCCGC CGGCGGTGGT GGCGGCCGCG 60
CCCGAGGAGA AGAAAGGGAA GGAGCCGGAG CGCGAGAAGC TGCCACCCAT CGTGTCGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	96.59	0.00e+00	1426.00
IUUC-Apl-003589	Anas platyrhynchos	86.32	0.00e+00	1269.00
IUUC-Aca-004350	Anolis carolinensis	81.23	0.00e+00	1186.00
IUUC-Ago-007908	Ashbya gossypii	35.06	6.00e-80	291.00
IUUC-Acl-008288	Aspergillus clavatus	35.30	4.00e-96	346.00
IUUC-Afl-008402	Aspergillus flavus	33.77	3.00e-89	322.00
IUUC-Afu-008762	Aspergillus fumigatus	34.26	4.00e-93	336.00
IUUC-Ani-009176	Aspergillus nidulans	35.49	5.00e-92	332.00
IUUC-Ang-009791	Aspergillus niger	35.97	4.00e-92	332.00
IUUC-Aor-009921	Aspergillus oryzae	33.61	1.00e-88	321.00
IUUC-Ate-010295	Aspergillus terreus	35.82	2.00e-99	357.00
IUUC-Ame-010660	Astyanax mexicanus	82.61	1.00e-153	535.00
IUUC-Bgr-011981	Blumeria graminis	32.24	5.00e-92	332.00
IUUC-Bta-012945	Bos taurus	96.63	0.00e+00	1398.00
IUUC-Bci-013697	Botrytis cinerea	33.50	1.00e-79	291.00
IUUC-Cja-019263	Callithrix jacchus	93.69	0.00e+00	1365.00
IUUC-Cfa-020486	Canis familiaris	97.37	0.00e+00	1299.00
IUUC-Cpo-021755	Cavia porcellus	93.94	0.00e+00	1387.00
IUUC-Csa-023814	Chlorocebus sabaeus	95.01	0.00e+00	1303.00
IUUC-Cho-024980	Choloepus hoffmanni	78.00	0.00e+00	1093.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	42.17	3.00e-96	346.00
IUUC-Dre-028551	Danio rerio	75.66	0.00e+00	1143.00
IUUC-Dno-029497	Dasypus novemcinctus	93.49	0.00e+00	1247.00
IUUC-Dor-030867	Dipodomys ordii	83.01	0.00e+00	1178.00
IUUC-Dse-031239	Dothistroma septosporum	29.57	3.00e-88	320.00
IUUC-Ete-032902	Echinops telfairi	79.62	0.00e+00	1142.00
IUUC-Eca-033678	Equus caballus	96.71	0.00e+00	1429.00
IUUC-Eeu-035262	Erinaceus europaeus	78.60	0.00e+00	1026.00
IUUC-Fca-035590	Felis catus	96.85	0.00e+00	1432.00
IUUC-Fal-037123	Ficedula albicollis	81.60	0.00e+00	1214.00
IUUC-Fox-037941	Fusarium oxysporum	40.80	1.00e-100	361.00
IUUC-Fso-038388	Fusarium solani	41.39	6.00e-103	369.00
IUUC-Gmo-039553	Gadus morhua	66.20	0.00e+00	848.00
IUUC-Ggr-040110	Gaeumannomyces graminis	40.20	1.00e-96	347.00
IUUC-Gga-040406	Gallus gallus	86.44	0.00e+00	1300.00
IUUC-Gac-042141	Gasterosteus aculeatus	75.83	0.00e+00	1093.00
IUUC-Ggo-045504	Gorilla gorilla	93.58	0.00e+00	1372.00
IUUC-Hsa-045786	Homo sapiens	94.35	0.00e+00	1379.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	90.26	0.00e+00	1219.00
IUUC-Kpa-049152	Komagataella pastoris	33.98	3.00e-74	273.00
IUUC-Lch-049824	Latimeria chalumnae	81.77	0.00e+00	1102.00
IUUC-Loc-052173	Lepisosteus oculatus	78.60	0.00e+00	1191.00
IUUC-Laf-054017	Loxodonta africana	95.78	0.00e+00	1319.00
IUUC-Mcc-055713	Macaca mulatta	94.63	0.00e+00	1354.00
IUUC-Meu-056212	Macropus eugenii	69.72	1.00e-117	416.00
IUUC-Mor-057045	Magnaporthe oryzae	36.14	2.00e-88	320.00
IUUC-Mla-059187	Melampsora laricipopulina	43.86	2.00e-86	312.00
IUUC-Mga-059884	Meleagris gallopavo	80.16	0.00e+00	1157.00
IUUC-Mmr-061344	Microcebus murinus	94.66	0.00e+00	1381.00
IUUC-Mdo-062653	Monodelphis domestica	87.87	0.00e+00	1306.00
IUUC-Mmu-063775	Mus musculus	92.05	0.00e+00	1303.00
IUUC-Mpu-066069	Mustela putorius furo	97.13	0.00e+00	1303.00
IUUC-Mlu-067925	Myotis lucifugus	95.48	0.00e+00	1372.00
IUUC-Nfi-068439	Neosartorya fischeri	34.26	6.00e-93	335.00
IUUC-Ncr-068903	Neurospora crassa	37.80	6.00e-92	332.00
IUUC-Nle-070046	Nomascus leucogenys	94.12	0.00e+00	1381.00
IUUC-Opr-071085	Ochotona princeps	79.19	1.00e-136	479.00
IUUC-Ont-072126	Oreochromis niloticus	72.62	0.00e+00	1141.00
IUUC-Oan-072933	Ornithorhynchus anatinus	89.35	0.00e+00	1173.00
IUUC-Ocu-073800	Oryctolagus cuniculus	96.08	0.00e+00	1268.00
IUUC-Ola-086988	Oryzias latipes	76.16	0.00e+00	1099.00
IUUC-Oga-088117	Otolemur garnettii	96.56	0.00e+00	1126.00
IUUC-Oar-089371	Ovis aries	96.85	0.00e+00	1373.00
IUUC-Ptr-090551	Pan troglodytes	93.05	0.00e+00	1333.00
IUUC-Pan-092067	Papio anubis	95.14	0.00e+00	1360.00
IUUC-Psi-092963	Pelodiscus sinensis	86.42	0.00e+00	1262.00
IUUC-Pfo-096562	Poecilia formosa	70.94	0.00e+00	1111.00
IUUC-Pab-098680	Pongo abelii	94.76	0.00e+00	1384.00
IUUC-Pca-100986	Procavia capensis	76.21	0.00e+00	891.00
IUUC-Pva-102219	Pteropus vampyrus	80.46	0.00e+00	1065.00
IUUC-Pgr-103315	Puccinia graminis	36.76	3.00e-95	342.00
IUUC-Ptt-103736	Puccinia triticina	41.83	5.00e-94	338.00
IUUC-Rno-105270	Rattus norvegicus	89.84	0.00e+00	1301.00
IUUC-Sce-106306	Saccharomyces cerevisiae	34.45	2.00e-68	254.00
IUUC-Sha-106819	Sarcophilus harrisii	91.10	0.00e+00	1367.00
IUUC-Spo-108271	Schizosaccharomyces pombe	32.17	2.00e-84	306.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	31.47	2.00e-84	307.00
IUUC-Sar-113134	Sorex araneus	86.71	0.00e+00	1239.00
IUUC-Tgu-117166	Taeniopygia guttata	84.81	0.00e+00	1252.00
IUUC-Tsy-118898	Tarsius syrichta	81.86	0.00e+00	1083.00
IUUC-Tre-122108	Trichoderma reesei	39.26	6.00e-89	322.00
IUUC-Tvi-122644	Trichoderma virens	39.44	1.00e-94	341.00
IUUC-Tme-127004	Tuber melanosporum	34.81	6.00e-102	365.00
IUUC-Tbe-127292	Tupaia belangeri	79.59	0.00e+00	1046.00
IUUC-Ttr-128352	Tursiops truncatus	93.29	0.00e+00	1326.00
IUUC-Vda-129969	Verticillium dahliae	40.57	2.00e-92	334.00
IUUC-Vpa-130218	Vicugna pacos	95.73	0.00e+00	1021.00
IUUC-Xtr-132594	Xenopus tropicalis	78.96	0.00e+00	1160.00
IUUC-Xma-134157	Xiphophorus maculatus	75.19	0.00e+00	1024.00
IUUC-Yli-134470	Yarrowia lipolytica	30.81	9.00e-76	278.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence