iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Yli-134470

Ensembl Protein ID

CAG81049

UniProt Accession

Q6C901; Q6C901_YARLI

Genbank Protein ID

CAG81049.1

Protein Name

YALI0D15444p

Genbank Nucleotide ID

CR382130

Gene Name

YALI0_D15444g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YALI0_D15444g	CAG81049	CAG81049

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.70e-78	261.6	670	999

Active Site

Position(s)	Description	Evidence
969	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllgk 103
            + kk+l+vefvgE g+d gG+ +e++ ll  +l+np  +lf+ +e+++++++ np  + +    l+ ++++G++ g+al+++ +ldlpl+++++k+llg 
   Q: 670  GNYKKSLRVEFVGEPGIDVGGIRKEWFLLLKTALFNPARNLFVEDEESHYCWF-NPGCKAQ-DGDLREYRLAGVITGLALYNSSMLDLPLPPVVFKKLLGC 768
           57899*****************************************9999988.8988875.59************************************* PP
   S: 104  klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviple 204
           ++ led+  v+p++ +sl ++++  es++e l+l  ++ +++   g  k+ +L+++G++++Vt  N+++Yv+++v++ l+++i + +++ ++Gf++v+  +
   Q: 769  PVGLEDFTVVNPTVGRSLSQLLKFTESEVESLNLSYNVIIDS--EGVKKSCDLISNGSHVSVTTRNRRDYVSRLVKFFLETSISTTFAEYKKGFHSVVGGN 867
           **********************99888888876666666555..77788888************************************************* PP
   S: 205  llslFteeelellicGe.eeidvedlkketkykggytedsp....aiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlP 299
            lslF++eele l+ G+ e +d+ +lk  t+y++ +t ++p    +++wFw+  e++++e++k++L+F+Tgs+r+P+ G+ +++   f i  ++ d dr+P
   Q: 868  ALSLFRPEELEALVKGSsEPLDIGTLKTVTRYQN-FTTEDPeselVVRWFWKWAENLEEEKQKKLLRFITGSDRIPATGISNMN---FKITFSGPDcDRFP 964
           *****************99***********9977.444333122279*************************************...7777777777**** PP
   S: 300  ssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
            s+TCfn L++  Yss +++ +k+ +A++e++gF+
   Q: 965  VSHTCFNELCVYGYSSRQKFIDKIVMAMNESEGFG 999
           **********************************8 PP

Organism

Yarrowia lipolytica

Protein Sequence
(Fasta)

MFNLPWQKSR GSKSSPSTVL SELHVGSSVP TIPASKNRPN SSRSITTTCS SCGSSISLPP 60
HLRSFLCSTC NTIKDLRSTS VRGGDLEPVS CALLEKWIET PHSLCKNLFD SFSSPTCLNA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCAACT TGCCGTGGCA GAAATCCCGC GGCTCAAAGT CGTCGCCCAG TACTGTACTA 60
AGCGAGCTAC ATGTTGGCAG TTCTGTTCCG ACCATTCCAG CTTCTAAAAA CCGCCCAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

yli:YALI0D15444g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	35.35	5.00e-90	323.00
IUUC-Atr-003144	Amborella trichopoda	34.87	3.00e-70	256.00
IUUC-Apl-003589	Anas platyrhynchos	35.15	2.00e-83	301.00
IUUC-Aca-004350	Anolis carolinensis	36.36	1.00e-87	315.00
IUUC-Ago-007908	Ashbya gossypii	35.06	3.00e-106	377.00
IUUC-Acl-008288	Aspergillus clavatus	35.51	9.00e-119	419.00
IUUC-Afl-008402	Aspergillus flavus	36.07	1.00e-109	388.00
IUUC-Afu-008762	Aspergillus fumigatus	35.22	4.00e-120	424.00
IUUC-Ani-009176	Aspergillus nidulans	36.85	9.00e-117	412.00
IUUC-Ang-009791	Aspergillus niger	35.19	8.00e-114	403.00
IUUC-Aor-009921	Aspergillus oryzae	35.91	9.00e-110	389.00
IUUC-Ate-010295	Aspergillus terreus	35.97	2.00e-117	415.00
IUUC-Ame-010768	Astyanax mexicanus	32.30	1.00e-71	263.00
IUUC-Bgr-011981	Blumeria graminis	36.06	1.00e-111	395.00
IUUC-Bta-012945	Bos taurus	36.09	3.00e-88	317.00
IUUC-Bci-013697	Botrytis cinerea	32.61	1.00e-99	355.00
IUUC-Cel-018150	Caenorhabditis elegans	29.19	2.00e-51	195.00
IUUC-Cja-019263	Callithrix jacchus	35.88	1.00e-87	315.00
IUUC-Cfa-020486	Canis familiaris	35.76	4.00e-90	323.00
IUUC-Cpo-021755	Cavia porcellus	35.56	1.00e-90	325.00
IUUC-Cre-022790	Chlamydomonas reinhardtii	38.53	1.00e-56	211.00
IUUC-Csa-023814	Chlorocebus sabaeus	35.76	5.00e-76	276.00
IUUC-Cho-024980	Choloepus hoffmanni	32.59	2.00e-61	228.00
IUUC-Cin-025643	Ciona intestinalis	33.97	5.00e-65	240.00
IUUC-Csv-026282	Ciona savignyi	33.97	8.00e-58	216.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	39.71	2.00e-103	369.00
IUUC-Cme-027151	Cyanidioschyzon merolae	33.20	1.00e-69	256.00
IUUC-Dre-028551	Danio rerio	37.39	3.00e-88	317.00
IUUC-Dno-029497	Dasypus novemcinctus	36.09	8.00e-89	319.00
IUUC-Dor-030867	Dipodomys ordii	32.48	5.00e-72	263.00
IUUC-Dse-031239	Dothistroma septosporum	32.84	2.00e-101	362.00
IUUC-Dme-032035	Drosophila melanogaster	37.47	1.00e-61	229.00
IUUC-Ete-032902	Echinops telfairi	34.14	2.00e-83	301.00
IUUC-Eca-033678	Equus caballus	31.34	5.00e-90	323.00
IUUC-Eeu-035109	Erinaceus europaeus	33.82	1.00e-60	225.00
IUUC-Fca-035590	Felis catus	35.96	6.00e-91	326.00
IUUC-Fal-037123	Ficedula albicollis	33.40	3.00e-73	268.00
IUUC-Fox-037941	Fusarium oxysporum	34.82	6.00e-112	397.00
IUUC-Fso-038388	Fusarium solani	33.64	2.00e-109	389.00
IUUC-Gmo-039553	Gadus morhua	35.68	1.00e-69	255.00
IUUC-Ggr-040110	Gaeumannomyces graminis	39.92	3.00e-107	381.00
IUUC-Gga-040406	Gallus gallus	35.35	1.00e-88	318.00
IUUC-Gac-042141	Gasterosteus aculeatus	31.45	4.00e-83	300.00
IUUC-Ggo-045504	Gorilla gorilla	35.88	1.00e-87	315.00
IUUC-Hsa-045786	Homo sapiens	35.88	2.00e-87	315.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	31.71	2.00e-69	254.00
IUUC-Kpa-049152	Komagataella pastoris	37.48	1.00e-101	362.00
IUUC-Lch-049824	Latimeria chalumnae	36.56	4.00e-71	260.00
IUUC-Loc-052173	Lepisosteus oculatus	33.87	6.00e-96	343.00
IUUC-Laf-054017	Loxodonta africana	35.88	2.00e-88	317.00
IUUC-Mcc-055713	Macaca mulatta	35.88	9.00e-88	315.00
IUUC-Meu-056061	Macropus eugenii	35.05	5.00e-67	247.00
IUUC-Mor-057045	Magnaporthe oryzae	34.64	9.00e-108	383.00
IUUC-Mla-059187	Melampsora laricipopulina	39.50	3.00e-91	327.00
IUUC-Mga-059884	Meleagris gallopavo	38.24	2.00e-84	304.00
IUUC-Mmr-061344	Microcebus murinus	34.95	1.00e-88	319.00
IUUC-Mdo-062653	Monodelphis domestica	36.02	1.00e-87	315.00
IUUC-Mmu-063775	Mus musculus	36.94	2.00e-89	321.00
IUUC-Mpu-066069	Mustela putorius furo	35.56	6.00e-90	323.00
IUUC-Mlu-067925	Myotis lucifugus	36.09	1.00e-88	318.00
IUUC-Nfi-068439	Neosartorya fischeri	35.07	3.00e-119	421.00
IUUC-Ncr-068903	Neurospora crassa	35.75	5.00e-107	380.00
IUUC-Nle-070046	Nomascus leucogenys	34.95	2.00e-88	318.00
IUUC-Opr-070891	Ochotona princeps	29.75	1.00e-50	192.00
IUUC-Ont-072126	Oreochromis niloticus	31.50	6.00e-87	313.00
IUUC-Oan-072933	Ornithorhynchus anatinus	35.67	3.00e-87	313.00
IUUC-Ocu-073800	Oryctolagus cuniculus	36.09	1.00e-88	318.00
IUUC-Ola-086988	Oryzias latipes	32.58	4.00e-87	313.00
IUUC-Oga-088117	Otolemur garnettii	35.67	3.00e-87	313.00
IUUC-Oar-089371	Ovis aries	36.09	4.00e-88	317.00
IUUC-Ptr-090551	Pan troglodytes	35.88	2.00e-87	314.00
IUUC-Pan-092067	Papio anubis	35.88	1.00e-87	315.00
IUUC-Psi-092963	Pelodiscus sinensis	36.52	8.00e-88	316.00
IUUC-Pma-094643	Petromyzon marinus	36.27	5.00e-71	260.00
IUUC-Ppa-095354	Physcomitrella patens	34.24	2.00e-78	285.00
IUUC-Pfo-096562	Poecilia formosa	32.15	7.00e-88	316.00
IUUC-Pab-098680	Pongo abelii	35.88	1.00e-87	315.00
IUUC-Pca-100869	Procavia capensis	34.23	3.00e-65	241.00
IUUC-Pva-102219	Pteropus vampyrus	34.82	3.00e-71	260.00
IUUC-Pgr-103315	Puccinia graminis	38.21	1.00e-93	336.00
IUUC-Ptt-103736	Puccinia triticina	39.29	3.00e-96	344.00
IUUC-Rno-105270	Rattus norvegicus	36.73	2.00e-89	321.00
IUUC-Sce-106306	Saccharomyces cerevisiae	34.48	8.00e-98	349.00
IUUC-Sha-106819	Sarcophilus harrisii	35.76	3.00e-90	324.00
IUUC-Sja-107974	Schizosaccharomyces japonicus	45.08	1.00e-47	182.00
IUUC-Spo-108271	Schizosaccharomyces pombe	38.29	4.00e-103	367.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	34.28	3.00e-105	374.00
IUUC-Smo-108858	Selaginella moellendorffii	34.38	3.00e-80	290.00
IUUC-Sar-113293	Sorex araneus	35.05	5.00e-68	250.00
IUUC-Ssc-115441	Sus scrofa	36.09	4.00e-88	317.00
IUUC-Tgu-117166	Taeniopygia guttata	35.56	1.00e-83	302.00
IUUC-Tru-118368	Takifugu rubripes	35.54	2.00e-72	265.00
IUUC-Tsy-118898	Tarsius syrichta	32.70	5.00e-73	266.00
IUUC-Tni-120143	Tetraodon nigroviridis	36.03	4.00e-73	267.00
IUUC-Tre-122108	Trichoderma reesei	34.98	4.00e-102	364.00
IUUC-Tvi-122644	Trichoderma virens	35.36	1.00e-107	382.00
IUUC-Tme-127004	Tuber melanosporum	40.26	6.00e-113	400.00
IUUC-Tbe-127292	Tupaia belangeri	30.35	9.00e-61	226.00
IUUC-Ttr-128352	Tursiops truncatus	34.61	9.00e-81	292.00
IUUC-Vda-129969	Verticillium dahliae	40.17	2.00e-103	369.00
IUUC-Vpa-130448	Vicugna pacos	32.23	2.00e-66	245.00
IUUC-Xtr-132719	Xenopus tropicalis	32.44	3.00e-68	251.00
IUUC-Xma-134157	Xiphophorus maculatus	35.71	2.00e-74	271.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence