iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	miRNAMap	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	6.50e-15	55.6	189	261

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvg....geeffahkivLaasSsvFyalflmeleesksklmveik..dvqpevfrallkFlYtgklde 67
           aDv +vvg    +++++ahk vL+  S vF a+f+++l  ++ ++  ei+  dv+p++f allkFlY++++++
   Q: 189  ADVFFVVGiddsRQRIPAHKFVLSIGSVVFDAMFNGGLTPKNTEEALEIElpDVEPSAFLALLKFLYSDEVKI 261
           69*****88789***************************66556666666659****************9986 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MSSENGVEVS DPEEGPCNRR QSSGSCEPEN SDSIFQGENQ LYPSRRTAAN HEHQQQQKSS 60
STLDLPANVL HEYASSSPPQ SSSRHVHSSS TSSLGEVAAL FGTRFPQDEG KQASNVEKAV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAAAGAAT TAAATTTATC TTCTTCCTTT AGCCTCCATA ATTGTGTAGA TTTTTAGAAG 60
TTTATTCTTT GTTTGTTTCG TTATTTCGTT ATTATATCGT GCCTTTTCCA CTGTTTACGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR012983--PHR
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF08005--PHR

SMART

SM00875--BACK
SM00225--BTB

Gene Ontology

GO:0005829--C:cytosol
GO:0019005--C:SCF ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0022008--P:neurogenesis
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030162--P:regulation of proteolysis

KEGG

cel:CELE_F38H4.7

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002337	Ailuropoda melanoleuca	54.93	1.00e-139	488.00
IUUC-Apl-003687	Anas platyrhynchos	42.99	8.00e-97	346.00
IUUC-Aca-004409	Anolis carolinensis	54.75	2.00e-140	491.00
IUUC-Ame-011722	Astyanax mexicanus	57.47	8.00e-149	519.00
IUUC-Bta-013384	Bos taurus	58.35	4.00e-150	523.00
IUUC-Bol-016130	Brassica oleracea	26.03	6.00e-14	71.60
IUUC-Cja-019900	Callithrix jacchus	57.82	7.00e-149	519.00
IUUC-Cfa-020164	Canis familiaris	53.15	1.00e-119	421.00
IUUC-Cpo-021442	Cavia porcellus	55.43	2.00e-141	494.00
IUUC-Csa-023065	Chlorocebus sabaeus	55.28	7.00e-142	495.00
IUUC-Cho-025005	Choloepus hoffmanni	40.09	4.00e-93	333.00
IUUC-Cin-025192	Ciona intestinalis	52.95	5.00e-138	483.00
IUUC-Csv-026025	Ciona savignyi	52.26	1.00e-128	451.00
IUUC-Dre-028297	Danio rerio	57.82	7.00e-151	526.00
IUUC-Dno-029188	Dasypus novemcinctus	55.26	3.00e-140	490.00
IUUC-Dor-031079	Dipodomys ordii	52.83	4.00e-134	469.00
IUUC-Dme-032181	Drosophila melanogaster	42.92	6.00e-98	350.00
IUUC-Ete-032361	Echinops telfairi	38.15	6.00e-87	313.00
IUUC-Eca-033745	Equus caballus	50.51	7.00e-103	365.00
IUUC-Eeu-035112	Erinaceus europaeus	47.12	1.00e-47	182.00
IUUC-Fca-036108	Felis catus	43.94	1.00e-95	342.00
IUUC-Fal-037173	Ficedula albicollis	60.15	1.00e-139	488.00
IUUC-Gmo-038536	Gadus morhua	57.30	2.00e-148	517.00
IUUC-Gga-040414	Gallus gallus	58.64	1.00e-152	531.00
IUUC-Gac-042278	Gasterosteus aculeatus	58.28	1.00e-150	525.00
IUUC-Gma-043440	Glycine max	29.58	5.00e-13	68.60
IUUC-Ggo-044634	Gorilla gorilla	55.06	2.00e-140	491.00
IUUC-Hsa-046206	Homo sapiens	58.81	5.00e-151	526.00
IUUC-Itr-048353	Ictidomys tridecemlineatus	58.28	2.00e-151	527.00
IUUC-Lch-050091	Latimeria chalumnae	54.83	8.00e-134	469.00
IUUC-Loc-052236	Lepisosteus oculatus	56.49	5.00e-146	509.00
IUUC-Laf-054062	Loxodonta africana	55.38	1.00e-140	491.00
IUUC-Mcc-055221	Macaca mulatta	43.47	2.00e-93	335.00
IUUC-Meu-056514	Macropus eugenii	43.53	8.00e-94	336.00
IUUC-Mga-059788	Meleagris gallopavo	42.99	7.00e-96	342.00
IUUC-Mmr-060924	Microcebus murinus	54.93	2.00e-140	490.00
IUUC-Mdo-062009	Monodelphis domestica	58.86	1.00e-153	535.00
IUUC-Mmu-064043	Mus musculus	57.43	6.00e-152	529.00
IUUC-Mpu-065960	Mustela putorius furo	58.90	4.00e-138	483.00
IUUC-Mlu-067926	Myotis lucifugus	54.77	6.00e-116	409.00
IUUC-Nle-069698	Nomascus leucogenys	39.66	2.00e-93	334.00
IUUC-Opr-070931	Ochotona princeps	44.18	1.00e-95	342.00
IUUC-Ont-071481	Oreochromis niloticus	58.28	2.00e-151	527.00
IUUC-Oan-072789	Ornithorhynchus anatinus	41.23	5.00e-92	330.00
IUUC-Ocu-074518	Oryctolagus cuniculus	56.67	4.00e-121	426.00
IUUC-Ola-086590	Oryzias latipes	58.05	2.00e-151	528.00
IUUC-Oga-088011	Otolemur garnettii	58.39	2.00e-148	517.00
IUUC-Oar-089514	Ovis aries	58.69	1.00e-135	474.00
IUUC-Ptr-091613	Pan troglodytes	55.06	2.00e-140	491.00
IUUC-Pan-092323	Papio anubis	55.06	2.00e-141	494.00
IUUC-Psi-094048	Pelodiscus sinensis	55.46	9.00e-141	491.00
IUUC-Pma-094699	Petromyzon marinus	57.37	2.00e-150	524.00
IUUC-Pfo-097138	Poecilia formosa	58.50	7.00e-145	506.00
IUUC-Pab-098330	Pongo abelii	54.83	3.00e-140	490.00
IUUC-Pca-100556	Procavia capensis	43.15	1.00e-85	308.00
IUUC-Pva-102923	Pteropus vampyrus	39.96	3.00e-93	334.00
IUUC-Rno-105116	Rattus norvegicus	55.06	1.00e-141	495.00
IUUC-Sha-106477	Sarcophilus harrisii	60.15	1.00e-143	501.00
IUUC-Ssl-108583	Sclerotinia sclerotiorum	33.33	1.80e-02	33.10
IUUC-Sar-113466	Sorex araneus	58.33	6.00e-133	465.00
IUUC-Ssc-115374	Sus scrofa	54.79	1.00e-139	488.00
IUUC-Tgu-116583	Taeniopygia guttata	59.40	1.00e-150	524.00
IUUC-Tru-118211	Takifugu rubripes	58.50	8.00e-152	528.00
IUUC-Tsy-119141	Tarsius syrichta	39.87	2.00e-93	334.00
IUUC-Tni-120528	Tetraodon nigroviridis	58.28	1.00e-151	528.00
IUUC-Tvi-122627	Trichoderma virens	34.78	6.00e-05	41.60
IUUC-Tbe-127750	Tupaia belangeri	41.63	5.00e-87	313.00
IUUC-Ttr-128417	Tursiops truncatus	42.64	4.00e-84	303.00
IUUC-Vpa-130673	Vicugna pacos	53.69	3.00e-130	456.00
IUUC-Xtr-132426	Xenopus tropicalis	59.09	6.00e-153	532.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence