iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-051837

Ensembl Protein ID

ENSLOCP00000019950.1

UniProt Accession

W5NH41; W5NH41_LEPOC

Genbank Protein ID

ENSLOCP00000019950

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01008861

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000016186.1	ENSLOCT00000019983.1	ENSLOCP00000019950.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	50.91	4.00e-111	399.00	IUUC-Hsa-046376
E3 activity/RING/RING	47.78	7.00e-100	361.00	IUUC-Mmu-063207
E3 activity/RING/RING	49.49	2.00e-105	379.00	IUUC-Rno-105641

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

QMTDGMATAN CLSSSQINGT DNEKLVKPKT KLHALLQHAG ADKDIFTMKE IMFYLGQYIM 60
DKQLYDKKQQ HIVHCTNDLL GDVLGVNSFS VKEPRNLYAL ISKNLIAVKN EVYEDSQTAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGATGACTG ACGGAATGGC AACTGCTAAC TGCTTAAGCA GTTCACAGAT AAATGGGACA 60
GATAATGAAA AGCTCGTAAG TCATTTCCTT GGCCTTTTGT CACACAGTTT GAAATAATGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR028340--Mdm2
IPR015459--MDM2_E3_ligase
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002039	Ailuropoda melanoleuca	50.40	9.00e-112	397.00
IUUC-Apl-003193	Anas platyrhynchos	51.41	6.00e-114	404.00
IUUC-Aca-004305	Anolis carolinensis	50.33	8.00e-97	347.00
IUUC-Ame-010675	Astyanax mexicanus	58.43	1.00e-128	453.00
IUUC-Bta-013270	Bos taurus	49.90	9.00e-109	387.00
IUUC-Cja-019744	Callithrix jacchus	50.10	8.00e-111	394.00
IUUC-Cfa-020807	Canis familiaris	49.27	8.00e-100	357.00
IUUC-Cpo-022182	Cavia porcellus	49.80	5.00e-107	381.00
IUUC-Csa-023541	Chlorocebus sabaeus	50.51	2.00e-108	386.00
IUUC-Cin-025448	Ciona intestinalis	23.08	3.00e-16	78.20
IUUC-Csv-026151	Ciona savignyi	40.96	2.00e-14	72.40
IUUC-Dre-028419	Danio rerio	56.21	8.00e-120	423.00
IUUC-Dno-028950	Dasypus novemcinctus	50.10	9.00e-105	374.00
IUUC-Dor-031048	Dipodomys ordii	47.64	1.00e-52	201.00
IUUC-Ete-032264	Echinops telfairi	40.87	2.00e-82	300.00
IUUC-Eca-033301	Equus caballus	48.80	2.00e-108	386.00
IUUC-Eeu-035005	Erinaceus europaeus	46.11	4.00e-89	322.00
IUUC-Fca-035454	Felis catus	50.10	2.00e-108	386.00
IUUC-Fal-036720	Ficedula albicollis	54.28	1.00e-51	196.00
IUUC-Gmo-039296	Gadus morhua	44.48	6.00e-52	197.00
IUUC-Gga-040251	Gallus gallus	52.88	6.00e-114	404.00
IUUC-Ggo-044948	Gorilla gorilla	49.39	1.00e-103	370.00
IUUC-Hsa-046376	Homo sapiens	50.51	8.00e-109	387.00
IUUC-Itr-048328	Ictidomys tridecemlineatus	50.20	3.00e-111	395.00
IUUC-Lch-050037	Latimeria chalumnae	61.64	4.00e-66	245.00
IUUC-Laf-053483	Loxodonta africana	47.47	5.00e-106	377.00
IUUC-Mcc-055294	Macaca mulatta	50.51	8.00e-109	387.00
IUUC-Mga-060007	Meleagris gallopavo	51.08	1.00e-108	386.00
IUUC-Mmr-060673	Microcebus murinus	49.60	4.00e-116	411.00
IUUC-Mdo-063057	Monodelphis domestica	53.25	9.00e-115	407.00
IUUC-Mmu-063207	Mus musculus	45.53	2.00e-90	326.00
IUUC-Mpu-065836	Mustela putorius furo	50.20	9.00e-113	400.00
IUUC-Mlu-068193	Myotis lucifugus	51.31	2.00e-109	389.00
IUUC-Nle-069927	Nomascus leucogenys	50.51	1.00e-108	386.00
IUUC-Opr-070590	Ochotona princeps	47.18	8.00e-95	340.00
IUUC-Ont-071984	Oreochromis niloticus	50.00	3.00e-97	348.00
IUUC-Oan-072744	Ornithorhynchus anatinus	52.32	2.00e-105	375.00
IUUC-Ocu-074071	Oryctolagus cuniculus	49.80	5.00e-111	395.00
IUUC-Ola-087329	Oryzias latipes	47.29	3.00e-91	328.00
IUUC-Oga-088135	Otolemur garnettii	47.08	3.00e-100	358.00
IUUC-Oar-090078	Ovis aries	50.00	1.00e-112	400.00
IUUC-Ptr-091399	Pan troglodytes	50.51	1.00e-108	387.00
IUUC-Pan-092720	Papio anubis	50.51	8.00e-109	387.00
IUUC-Psi-093591	Pelodiscus sinensis	50.11	2.00e-97	349.00
IUUC-Pma-094500	Petromyzon marinus	64.29	1.00e-18	86.30
IUUC-Pfo-096316	Poecilia formosa	51.33	4.00e-100	358.00
IUUC-Pab-097696	Pongo abelii	50.61	8.00e-110	390.00
IUUC-Pca-100974	Procavia capensis	47.98	3.00e-108	385.00
IUUC-Pva-102488	Pteropus vampyrus	47.37	5.00e-97	348.00
IUUC-Rno-105641	Rattus norvegicus	47.87	9.00e-97	347.00
IUUC-Sha-107314	Sarcophilus harrisii	52.75	1.00e-118	419.00
IUUC-Sar-112938	Sorex araneus	48.99	6.00e-104	370.00
IUUC-Ssc-115495	Sus scrofa	49.39	1.00e-108	386.00
IUUC-Tgu-116623	Taeniopygia guttata	52.04	2.00e-112	399.00
IUUC-Tru-117820	Takifugu rubripes	47.95	7.00e-90	324.00
IUUC-Tni-119793	Tetraodon nigroviridis	51.20	4.00e-50	192.00
IUUC-Tbe-127816	Tupaia belangeri	52.81	1.00e-62	233.00
IUUC-Ttr-129194	Tursiops truncatus	49.54	3.00e-71	262.00
IUUC-Vpa-130326	Vicugna pacos	46.64	1.00e-96	346.00
IUUC-Xtr-132216	Xenopus tropicalis	49.50	2.00e-109	389.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence