iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044736

UUCD1 version

UUC-GoG-00222

Ensembl Protein ID

ENSGGOP00000005391.2

UniProt Accession

G3QRX4; G3QRX4_GORGO

Protein Name

Uncharacterized protein

Gene Name

FBXO4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000005501.2	ENSGGOT00000005532.2	ENSGGOP00000005391.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	99.22	0.00e+00	758.00	IUUC-Hsa-046558

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MAGSEPRRGS NSPPPPFSDW GRLEAAILSG WKTFWQSVSK ERVARTTSRE EVDEAASTLM 60
RLPIDVQLYI LSFLSPHDLC QLGSTNHYWN ETVRDPILWR YFLLRDLPSW SSVDWKSLPD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGGCTGAC GCACTAGCGT GGCTCTGAGA CGCGTCACCC ACGCTGCGGG CAAGCCATGG 60
CGGGAAGCGA GCCGCGCAGG GGCAGTAACT CGCCGCCGCC GCCGTTCAGC GACTGGGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom

PROSITE

PS50181--FBOX

Pfam

PF00646--F-box

SMART

SM00256--FBOX

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0007568--P:aging
GO:0019725--P:cellular homeostasis
GO:0071479--P:cellular response to ionizing radiation
GO:0035726--P:common myeloid progenitor cell proliferation
GO:0048147--P:negative regulation of fibroblast proliferation
GO:1900181--P:negative regulation of protein localization to nucleus
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0010608--P:posttranscriptional regulation of gene expression
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:2000001--P:regulation of DNA damage checkpoint
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

ggo:101150092

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001232	Ailuropoda melanoleuca	91.06	0.00e+00	682.00
IUUC-Apl-004129	Anas platyrhynchos	63.45	1.00e-111	395.00
IUUC-Aca-005076	Anolis carolinensis	49.49	3.00e-110	391.00
IUUC-Aly-006351	Arabidopsis lyrata	37.21	1.00e-03	37.40
IUUC-Ath-007114	Arabidopsis thaliana	33.85	4.00e-04	38.50
IUUC-Ame-011122	Astyanax mexicanus	47.04	2.00e-86	312.00
IUUC-Bta-012449	Bos taurus	89.92	0.00e+00	682.00
IUUC-Bol-015278	Brassica oleracea	23.17	1.00e-04	40.80
IUUC-Cja-019890	Callithrix jacchus	95.09	0.00e+00	752.00
IUUC-Cfa-021134	Canis familiaris	89.66	0.00e+00	686.00
IUUC-Cpo-021693	Cavia porcellus	90.43	6.00e-171	592.00
IUUC-Csa-023540	Chlorocebus sabaeus	97.93	0.00e+00	749.00
IUUC-Dre-028667	Danio rerio	47.27	9.00e-87	313.00
IUUC-Dno-028997	Dasypus novemcinctus	90.98	0.00e+00	676.00
IUUC-Dor-030135	Dipodomys ordii	80.00	4.00e-154	537.00
IUUC-Ete-033149	Echinops telfairi	84.82	0.00e+00	644.00
IUUC-Eca-033292	Equus caballus	92.90	1.00e-176	611.00
IUUC-Eeu-034504	Erinaceus europaeus	73.15	2.00e-128	451.00
IUUC-Fca-036476	Felis catus	91.21	0.00e+00	741.00
IUUC-Fal-036711	Ficedula albicollis	64.92	3.00e-120	424.00
IUUC-Gmo-039592	Gadus morhua	48.60	1.00e-85	310.00
IUUC-Gga-040924	Gallus gallus	64.00	4.00e-126	444.00
IUUC-Gac-041791	Gasterosteus aculeatus	50.31	3.00e-84	305.00
IUUC-Hsa-046558	Homo sapiens	99.22	0.00e+00	758.00
IUUC-Itr-048956	Ictidomys tridecemlineatus	90.44	0.00e+00	678.00
IUUC-Lch-049817	Latimeria chalumnae	66.46	9.00e-129	452.00
IUUC-Loc-052226	Lepisosteus oculatus	51.77	1.00e-107	383.00
IUUC-Laf-054371	Loxodonta africana	90.18	0.00e+00	694.00
IUUC-Mcc-054904	Macaca mulatta	97.67	0.00e+00	748.00
IUUC-Meu-056192	Macropus eugenii	56.79	9.00e-92	329.00
IUUC-Mmr-061692	Microcebus murinus	90.44	0.00e+00	712.00
IUUC-Mdo-062666	Monodelphis domestica	75.41	9.00e-158	549.00
IUUC-Mmu-064223	Mus musculus	87.86	0.00e+00	713.00
IUUC-Mpu-066290	Mustela putorius furo	91.47	0.00e+00	691.00
IUUC-Mlu-067882	Myotis lucifugus	88.89	0.00e+00	694.00
IUUC-Nle-070162	Nomascus leucogenys	97.93	0.00e+00	747.00
IUUC-Opr-070789	Ochotona princeps	85.62	2.00e-74	272.00
IUUC-Ont-071690	Oreochromis niloticus	44.70	2.00e-77	282.00
IUUC-Oan-072928	Ornithorhynchus anatinus	73.46	4.00e-114	404.00
IUUC-Ocu-073857	Oryctolagus cuniculus	90.51	0.00e+00	638.00
IUUC-Ogu-078061	Oryza glumaepatula	31.15	7.00e-01	30.80
IUUC-Oni-083091	Oryza nivara	31.15	6.60e-01	30.80
IUUC-Oru-085096	Oryza rufipogon	31.15	6.70e-01	30.40
IUUC-Osa-086253	Oryza sativa	33.33	2.00e-01	30.40
IUUC-Ola-086607	Oryzias latipes	46.99	9.00e-84	303.00
IUUC-Oga-088929	Otolemur garnettii	92.90	0.00e+00	667.00
IUUC-Oar-089305	Ovis aries	94.14	5.00e-179	619.00
IUUC-Ptr-090813	Pan troglodytes	94.06	0.00e+00	723.00
IUUC-Pan-092924	Papio anubis	95.84	0.00e+00	673.00
IUUC-Psi-093237	Pelodiscus sinensis	67.47	2.00e-132	465.00
IUUC-Pfo-096259	Poecilia formosa	47.25	8.00e-86	310.00
IUUC-Pab-098292	Pongo abelii	98.19	0.00e+00	750.00
IUUC-Pva-102221	Pteropus vampyrus	91.99	0.00e+00	721.00
IUUC-Rno-105910	Rattus norvegicus	88.37	0.00e+00	713.00
IUUC-Sha-106998	Sarcophilus harrisii	76.55	4.00e-161	560.00
IUUC-Sar-113033	Sorex araneus	78.81	6.00e-172	596.00
IUUC-Ssc-115507	Sus scrofa	89.41	0.00e+00	651.00
IUUC-Tgu-116502	Taeniopygia guttata	63.25	6.00e-117	413.00
IUUC-Tru-118203	Takifugu rubripes	45.21	8.00e-75	273.00
IUUC-Tni-120249	Tetraodon nigroviridis	48.18	5.00e-76	277.00
IUUC-Tur-126361	Triticum urartu	26.15	2.00e-03	36.60
IUUC-Tbe-128100	Tupaia belangeri	67.60	2.00e-121	428.00
IUUC-Ttr-128299	Tursiops truncatus	81.91	0.00e+00	627.00
IUUC-Vpa-130394	Vicugna pacos	79.07	1.00e-165	575.00
IUUC-Xtr-131825	Xenopus tropicalis	55.32	7.00e-122	430.00
IUUC-Xma-133942	Xiphophorus maculatus	47.17	1.00e-88	320.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence