iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Hsa-046629

Ensembl Protein ID

ENSP00000345824.4

UniProt Accession

O95153; O75111; Q8N5W3; RIMB1_HUMAN

Genbank Protein ID

AAD11957.1; BAA31587.2; AAH31401.1

Protein Name

Peripheral-type benzodiazepine receptor-associated protein 1; Peripheral benzodiazepine receptor-interacting protein; RIMS-binding protein 1; TSPO-associated protein 1

Genbank Nucleotide ID

AF039571; AB014512; BC031401

Gene Name

TSPOAP1; BZRAP1; KIAA0612; RBP1; RIMBP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000005379.15	ENST00000581675.5	ENSP00000462518.1
ENSG00000005379.15	ENST00000268893.10	ENSP00000268893.6
ENSG00000005379.15	ENST00000343736.8	ENSP00000345824.4
ENSG00000005379.15	ENST00000580669.5	ENSP00000462822.1
ENSG00000005379.15	ENST00000582679.1	ENSP00000462710.1

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	AREsite	CircNet	miRTarBase
microRNA	TRANSFAC	RepTar	miRcode
RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	HINT
Mentha	InWeb_IM
Disease-associated Variation
ClinVar	GWASdb	OMIM
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	dbPTM
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.80e-19	69.7	1768	1827

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqn.......ddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            + + +dy++q+       + eL +++Gdv++v      d g  +g  el+g+rGl+P+nF e
   Q: 1768 SMVAAFDYNPQEsspnmdvEAELPFRAGDVITVF-GGMDDDGFYYG--ELNGQRGLVPSNFLE 1827
           566778888876222222246************9.999********..9************76 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MEQLTTLPRP GDPGAMEPWA LPTWHSWTPG RGGEPSSAAP SIADTPPAAL QLQELRSEES 60
SKPKGDGSSR PVGGTDPEGA EACLPSLGQQ ASSSGPACQR PEDEEVEAFL KAKLNMSFGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGAGGCTC CTGGACTGTA AGGGACCCCT GCAGTCCCCA GAGCAGAGGC CAGCAGGGGC 60
TGAGACTATG AGGCAAGCAG CCCATCGACC CAGGCCTCCT TAGGACCAGC CCAGCCACCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0496--Mitochondrion
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain

Interpro

IPR003961--FN3_dom
IPR013783--Ig-like_fold
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50853--FN3
PS50002--SH3

Pfam

PF07653--SH3_2
PF14604--SH3_9

SMART

SM00060--FN3
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0098793--C:presynapse
GO:0030156--F:benzodiazepine receptor binding
GO:0014047--P:glutamate secretion
GO:0007269--P:neurotransmitter secretion

KEGG

hsa:9256

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002320	Ailuropoda melanoleuca	82.53	0.00e+00	2372.00
IUUC-Apl-003247	Anas platyrhynchos	49.94	0.00e+00	1328.00
IUUC-Bta-013577	Bos taurus	80.00	0.00e+00	1496.00
IUUC-Cel-018438	Caenorhabditis elegans	34.96	8.00e-56	213.00
IUUC-Cfa-020327	Canis familiaris	83.51	0.00e+00	2470.00
IUUC-Cpo-022129	Cavia porcellus	81.39	0.00e+00	2466.00
IUUC-Csa-023615	Chlorocebus sabaeus	95.91	0.00e+00	2914.00
IUUC-Cin-025483	Ciona intestinalis	45.92	2.00e-39	155.00
IUUC-Dno-028999	Dasypus novemcinctus	80.66	0.00e+00	2145.00
IUUC-Dor-031115	Dipodomys ordii	81.82	0.00e+00	2430.00
IUUC-Ete-032231	Echinops telfairi	64.68	0.00e+00	696.00
IUUC-Eca-033541	Equus caballus	84.24	0.00e+00	2410.00
IUUC-Eeu-034866	Erinaceus europaeus	78.11	0.00e+00	1553.00
IUUC-Fca-035784	Felis catus	84.17	0.00e+00	2526.00
IUUC-Fal-037580	Ficedula albicollis	50.63	0.00e+00	1259.00
IUUC-Gga-040533	Gallus gallus	57.62	1.00e-160	561.00
IUUC-Gac-042384	Gasterosteus aculeatus	53.80	7.00e-140	492.00
IUUC-Ggo-044840	Gorilla gorilla	98.43	0.00e+00	2929.00
IUUC-Itr-048067	Ictidomys tridecemlineatus	86.51	0.00e+00	2155.00
IUUC-Lch-050621	Latimeria chalumnae	50.24	0.00e+00	957.00
IUUC-Loc-051977	Lepisosteus oculatus	51.89	0.00e+00	800.00
IUUC-Laf-054503	Loxodonta africana	80.39	0.00e+00	2352.00
IUUC-Mcc-054617	Macaca mulatta	96.03	0.00e+00	2842.00
IUUC-Meu-056497	Macropus eugenii	68.53	2.00e-155	544.00
IUUC-Mga-060003	Meleagris gallopavo	58.43	0.00e+00	1000.00
IUUC-Mmr-060759	Microcebus murinus	88.55	0.00e+00	2475.00
IUUC-Mdo-062431	Monodelphis domestica	72.51	0.00e+00	1200.00
IUUC-Mmu-063989	Mus musculus	81.10	0.00e+00	2502.00
IUUC-Mpu-066152	Mustela putorius furo	81.25	0.00e+00	2408.00
IUUC-Mlu-067161	Myotis lucifugus	82.88	0.00e+00	2357.00
IUUC-Nle-069018	Nomascus leucogenys	90.91	0.00e+00	2219.00
IUUC-Opr-070559	Ochotona princeps	79.58	0.00e+00	1551.00
IUUC-Ont-071243	Oreochromis niloticus	51.22	0.00e+00	810.00
IUUC-Oan-073533	Ornithorhynchus anatinus	60.66	1.00e-127	451.00
IUUC-Ocu-074839	Oryctolagus cuniculus	82.73	0.00e+00	2310.00
IUUC-Ola-086455	Oryzias latipes	50.93	6.00e-133	469.00
IUUC-Oga-087955	Otolemur garnettii	87.14	0.00e+00	2445.00
IUUC-Oar-090080	Ovis aries	80.03	0.00e+00	1742.00
IUUC-Ptr-091396	Pan troglodytes	95.10	0.00e+00	2984.00
IUUC-Pan-092386	Papio anubis	96.23	0.00e+00	2890.00
IUUC-Psi-094038	Pelodiscus sinensis	47.99	0.00e+00	778.00
IUUC-Pma-094667	Petromyzon marinus	47.05	1.00e-130	461.00
IUUC-Pfo-096696	Poecilia formosa	49.35	1.00e-175	611.00
IUUC-Pab-097590	Pongo abelii	97.31	0.00e+00	2945.00
IUUC-Pca-100489	Procavia capensis	81.10	0.00e+00	1315.00
IUUC-Pva-102429	Pteropus vampyrus	80.35	0.00e+00	2274.00
IUUC-Rno-105003	Rattus norvegicus	79.81	0.00e+00	2399.00
IUUC-Sha-106627	Sarcophilus harrisii	74.14	4.00e-144	506.00
IUUC-Sit-110232	Setaria italica	29.49	2.00e+00	28.90
IUUC-Ssc-115863	Sus scrofa	83.96	0.00e+00	2355.00
IUUC-Tni-120399	Tetraodon nigroviridis	52.47	4.00e-144	506.00
IUUC-Tbe-127326	Tupaia belangeri	86.38	0.00e+00	1510.00
IUUC-Xtr-132438	Xenopus tropicalis	51.29	6.00e-164	572.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence