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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-136555
Ensembl Protein ID ENSMUSP00000028105.6
UniProt Accession Q9CV28; Q3UPS0; Q9DCC9; MINY3_MOUSE
Genbank Protein ID AK002900; AK009891; AK143250; AL772342; AL845533; AL845533; AL772342; BC027202
Protein Name Ubiquitin carboxyl-terminal hydrolase MINDY-3;Deubiquitinating enzyme MINDY-3;Protein CARP
Genbank Nucleotide ID BAB22443.1; BAB26566.2; BAE25325.1; CAM13409.1; CAM13409.1; CAM18188.1; CAM18188.1; AAH27202.1
Gene Name MINDY3;Carp;Fam188a
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000026767.12 ENSMUST00000129489.7 ENSMUSP00000122501.1
ENSMUSG00000026767.12 ENSMUST00000154899.6 ENSMUSP00000121476.3
ENSMUSG00000026767.12 ENSMUST00000028105.12 ENSMUSP00000028105.6
ENSMUSG00000026767.12 ENSMUST00000144645.7 ENSMUSP00000116836.1
ENSMUSG00000026767.12 ENSMUST00000135397.7 ENSMUSP00000114789.1
ENSMUSG00000026767.12 ENSMUST00000124603.7 ENSMUSP00000117457.2
ENSMUSG00000026767.12 ENSMUST00000129993.2 ENSMUSP00000141479.1
ENSMUSG00000026767.12 ENSMUST00000129348.1 ENSMUSP00000121265.1
ENSMUSG00000026767.12 ENSMUST00000124515.1 ENSMUSP00000120193.1
ENSMUSG00000026767.12 ENSMUST00000151529.7 ENSMUSP00000122798.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitecircBasemiRTarBasemicroRNA
TRANSFACRAID2
Protein-protein Interaction
IIDiRefIndex
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
UniProtmUbiSiDa
Protein Expression/Proteomics
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/MIU 95.73 0.00e+00 847.00 IUUC-Hsa-136747
DUB/MINDY 95.73 0.00e+00 847.00 IUUC-Hsa-136747
Active Site
Position(s) Description Evidence
51 Nucleophile {ECO:0000250|UniProtKB:Q8N5J2}
286 Proton acceptor {ECO:0000250|UniProtKB:Q8N5J2}
Organism Mus musculus
Functional Description
(View)

Functional Description


     Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.
 Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.
Protein Sequence
(Fasta)
MSEVTKELLE LVWGTKSSPG LSDTIFCRWT QGFVFSESEG SALEQFEGGP CAVIAPVQAF 60
LLKKLLFSSE KSSWRDCSEE EQKELLCHTL CDIVESAYDS SGSYCLVSWL RGRTPEEAAR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-136555|DUB,MINDY;UBD,MIU|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGGAAGTCAG GCCGCTTCCG GCAGGGGAAA CTCCTAGTTG CCGCTTCGCC CGGCTTGACA 60
GGCGGTCTGT GCCGGCAGTG TGCTGCCCTC ACCCATCTCG ACCTCCCGTT CGCGTCCGAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-136555|DUB,MINDY;UBD,MIU|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0053--Apoptosis
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
Interpro

IPR025257--DUF4205
IPR011992--EF-hand-dom_pair
Pfam

PF13898--DUF4205
SMART

SM01174--DUF4205
Gene Ontology

GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0016807--F:cysteine-type carboxypeptidase activity
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0006915--P:apoptotic process
KEGG mmu:66960
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-136377 Aegilops tauschii 29.62 1.00e-44 174.00
IUUC-Aml-136379 Ailuropoda melanoleuca 95.07 0.00e+00 839.00
IUUC-Atr-136383 Amborella trichopoda 31.35 7.00e-42 164.00
IUUC-Apl-136385 Anas platyrhynchos 84.43 0.00e+00 637.00
IUUC-Aca-136389 Anolis carolinensis 81.84 0.00e+00 754.00
IUUC-Aly-136394 Arabidopsis lyrata 29.39 3.00e-45 176.00
IUUC-Ath-136396 Arabidopsis thaliana 31.06 5.00e-47 182.00
IUUC-Ame-136407 Astyanax mexicanus 72.95 0.00e+00 692.00
IUUC-Bta-136411 Bos taurus 94.38 0.00e+00 840.00
IUUC-Bdi-136416 Brachypodium distachyon 29.66 6.00e-46 179.00
IUUC-Bol-136419 Brassica oleracea 30.80 5.00e-44 172.00
IUUC-Bra-136421 Brassica rapa 31.56 1.00e-44 174.00
IUUC-Cja-136424 Callithrix jacchus 95.06 0.00e+00 840.00
IUUC-Cfa-136428 Canis familiaris 91.55 0.00e+00 750.00
IUUC-Cpo-136432 Cavia porcellus 94.83 0.00e+00 838.00
IUUC-Csa-136438 Chlorocebus sabaeus 95.73 0.00e+00 847.00
IUUC-Cho-136444 Choloepus hoffmanni 89.94 5.00e-163 566.00
IUUC-Cin-136447 Ciona intestinalis 41.41 2.00e-94 339.00
IUUC-Csv-136448 Ciona savignyi 41.76 3.00e-94 338.00
IUUC-Dre-136452 Danio rerio 72.65 0.00e+00 647.00
IUUC-Dno-136456 Dasypus novemcinctus 93.71 0.00e+00 830.00
IUUC-Dor-136461 Dipodomys ordii 91.21 0.00e+00 651.00
IUUC-Dme-136466 Drosophila melanogaster 41.86 2.00e-108 386.00
IUUC-Ete-136467 Echinops telfairi 72.30 0.00e+00 636.00
IUUC-Eca-136471 Equus caballus 95.28 0.00e+00 845.00
IUUC-Eeu-136476 Erinaceus europaeus 87.64 0.00e+00 738.00
IUUC-Fca-136477 Felis catus 94.17 0.00e+00 834.00
IUUC-Fal-136481 Ficedula albicollis 83.68 0.00e+00 743.00
IUUC-Gmo-136486 Gadus morhua 68.61 8.00e-178 616.00
IUUC-Gga-136491 Gallus gallus 84.08 0.00e+00 777.00
IUUC-Gac-136495 Gasterosteus aculeatus 68.83 0.00e+00 629.00
IUUC-Gma-136499 Glycine max 29.65 5.00e-43 169.00
IUUC-Ggo-136502 Gorilla gorilla 87.25 0.00e+00 750.00
IUUC-Hsa-136747 Homo sapiens 95.73 0.00e+00 847.00
IUUC-Hvu-136508 Hordeum vulgare 34.80 6.00e-39 154.00
IUUC-Itr-136510 Ictidomys tridecemlineatus 93.40 5.00e-105 373.00
IUUC-Lch-136515 Latimeria chalumnae 76.61 0.00e+00 699.00
IUUC-Lpe-136518 Leersia perrieri 28.05 1.00e-40 161.00
IUUC-Loc-136521 Lepisosteus oculatus 75.50 0.00e+00 704.00
IUUC-Laf-136527 Loxodonta africana 93.71 0.00e+00 828.00
IUUC-Mcc-136530 Macaca mulatta 95.73 0.00e+00 847.00
IUUC-Meu-136534 Macropus eugenii 58.08 1.00e-88 320.00
IUUC-Mga-136543 Meleagris gallopavo 83.53 0.00e+00 721.00
IUUC-Mmr-136547 Microcebus murinus 95.28 0.00e+00 845.00
IUUC-Mdo-136551 Monodelphis domestica 87.87 0.00e+00 826.00
IUUC-Mpu-136561 Mustela putorius furo 94.15 0.00e+00 628.00
IUUC-Mlu-136565 Myotis lucifugus 94.16 0.00e+00 835.00
IUUC-Nle-136572 Nomascus leucogenys 95.73 0.00e+00 847.00
IUUC-Opr-136576 Ochotona princeps 65.66 2.00e-132 465.00
IUUC-Ont-136579 Oreochromis niloticus 67.79 1.00e-179 622.00
IUUC-Oan-136582 Ornithorhynchus anatinus 85.39 0.00e+00 734.00
IUUC-Ocu-136585 Oryctolagus cuniculus 95.28 0.00e+00 841.00
IUUC-Oba-136589 Oryza barthii 29.63 2.00e-47 183.00
IUUC-Obr-136592 Oryza brachyantha 29.68 4.00e-46 179.00
IUUC-Ogl-136593 Oryza glaberrima 29.53 2.00e-47 183.00
IUUC-Ogu-136595 Oryza glumaepatula 29.53 2.00e-47 183.00
IUUC-Oin-136597 Oryza indica 29.89 2.00e-45 176.00
IUUC-Olo-136599 Oryza longistaminata 29.59 3.00e-47 183.00
IUUC-Oni-136602 Oryza nivara 29.53 2.00e-47 183.00
IUUC-Opu-136604 Oryza punctata 29.59 1.00e-47 184.00
IUUC-Oru-136606 Oryza rufipogon 29.53 2.00e-47 183.00
IUUC-Osa-136608 Oryza sativa 30.87 7.00e-33 134.00
IUUC-Ola-136610 Oryzias latipes 68.83 0.00e+00 645.00
IUUC-Oga-136614 Otolemur garnettii 94.41 0.00e+00 834.00
IUUC-Oar-136619 Ovis aries 94.16 0.00e+00 838.00
IUUC-Ptr-136623 Pan troglodytes 95.51 0.00e+00 845.00
IUUC-Pan-136627 Papio anubis 95.73 0.00e+00 847.00
IUUC-Psi-136631 Pelodiscus sinensis 85.26 3.00e-179 620.00
IUUC-Pma-136635 Petromyzon marinus 71.13 2.00e-47 181.00
IUUC-Pfo-136641 Poecilia formosa 66.01 0.00e+00 632.00
IUUC-Pab-136645 Pongo abelii 95.51 0.00e+00 843.00
IUUC-Pop-136650 Populus trichocarpa 30.12 2.00e-37 150.00
IUUC-Pca-136652 Procavia capensis 72.58 1.00e-180 625.00
IUUC-Ppe-136656 Prunus persica 27.76 5.00e-44 172.00
IUUC-Pva-136658 Pteropus vampyrus 85.84 0.00e+00 726.00
IUUC-Rno-136665 Rattus norvegicus 97.52 0.00e+00 867.00
IUUC-Sha-136671 Sarcophilus harrisii 87.64 0.00e+00 822.00
IUUC-Smo-136678 Selaginella moellendorffii 30.48 5.00e-44 172.00
IUUC-Sit-136680 Setaria italica 28.82 4.00e-36 145.00
IUUC-Sly-136683 Solanum lycopersicum 28.51 4.00e-43 169.00
IUUC-Sar-136685 Sorex araneus 84.95 0.00e+00 627.00
IUUC-Sbi-136688 Sorghum bicolor 31.90 2.00e-45 177.00
IUUC-Ssc-136691 Sus scrofa 95.06 0.00e+00 844.00
IUUC-Tgu-136694 Taeniopygia guttata 85.75 0.00e+00 735.00
IUUC-Tru-136698 Takifugu rubripes 67.75 0.00e+00 642.00
IUUC-Tsy-136703 Tarsius syrichta 90.11 0.00e+00 773.00
IUUC-Tni-136706 Tetraodon nigroviridis 70.47 0.00e+00 656.00
IUUC-Tca-136711 Theobroma cacao 29.16 3.00e-44 173.00
IUUC-Tae-136714 Triticum aestivum 29.44 8.00e-47 181.00
IUUC-Tur-136716 Triticum urartu 25.50 1.00e-28 121.00
IUUC-Tbe-136719 Tupaia belangeri 93.95 0.00e+00 764.00
IUUC-Ttr-136722 Tursiops truncatus 90.56 0.00e+00 800.00
IUUC-Vda-136727 Verticillium dahliae 24.36 6.50e-02 31.60
IUUC-Vpa-136729 Vicugna pacos 94.43 0.00e+00 773.00
IUUC-Vvi-136732 Vitis vinifera 28.84 4.00e-45 176.00
IUUC-Xtr-136734 Xenopus tropicalis 70.88 4.00e-178 617.00
IUUC-Xma-136738 Xiphophorus maculatus 68.01 0.00e+00 640.00
Created Date 25-Jun-2017

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