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Tag Content
UUCD2 ID IUUC-Cpo-021807
UUCD1 version UUC-CaP-01096
Ensembl Protein ID ENSCPOP00000001838.2
UniProt Accession H0UXL2; H0UXL2_CAVPO
Genbank Protein ID ENSCPOP00000001838
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAKN02034373
Gene Name USP25
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCPOG00000002031.3 ENSCPOT00000002058.2 ENSCPOP00000001838.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 8.70e-64 215.8 169 655
UBD/Alpha-Helix/UBA 9.30e-06 25.6 19 54
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +GlkN+gNtC++ +++Q+L+n+ e+r+l+l+    ++ ++l+++++++++ +++++l+ lf+ l+ +k+k+v+p++ +++lk++ ++ +
   Q: 169  VGLKNVGNTCWFSAIIQSLFNLLEFRRLVLNykppSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTKRKYVDPSRAVEILKDAFKS-N 256
           6******************************99988889999999999999*******************************99997.9 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
            ++qqD++Ef++ lld le+++++                  + +ee +++k k+++++lF g++    + +  +++ + +e f +++l
   Q: 257  DSQQQDVSEFTHKLLDWLEDAFQM------------------KAEEETDEEKPKNPMVELFYGRFLAVGVLE--GKKFENTEMFGQYPL 325
           **********************33..................123456788999************777664..444556899****** PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           +v+g +     +l++cLe+ + e e+e+   +++e+  k+    +++++++lP+vL+++L+Rf+f+++ +++eki++k+efp+ L l++
   Q: 326  QVNGFK-----DLHECLEAAMIEGEIES---LHSENSGKS---GQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDR 403
           ******.....9**************96...999998865...589******************************************* PP
   S: 264  fcts..................................................................................... 267
           ++++                                                                                     
   Q: 404  YMHRnreitrikreeikrlkdyltvlqqrlerylsygsgpkrfplvdvlqyalefasskpvctspvddidassqpsgsipsqtlpstae 492
           ****8888888888888888888888888888888888888888888877777777777777777777777777777777777666555 PP
   S: 268  .........peekqke......................................................................... 274
                    p     +                                                                         
   Q: 493  qqgapasepP-----Ntspasvaailsrsvvhkpftqsrippdlpmhpaprhiteeelsvlesclhrwrteiendtrdlqesisrihrt 576
           5555555550.....05555556666666666666666666666666666666666666677777777777777777777888888888 PP
   S: 275  ...........kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                      ++ Y+L+av+vH+G+++ GHY+ay+ +++++ W++++D  Vt++++ee ++++      ++aY+l+Y 
   Q: 577  ielmysdksmiQVPYRLHAVLVHEGQANAGHYWAYIFDHHESrWMKYNDIAVTKSSWEELVRDSFggyrnASAYCLMYI 655
           88888888888**************************966667***************99997779************6 PP
   

   UBD/Alpha-Helix/UBA
   S: 5    dkleqlve.MGF.dreealqaLraannnleaAveyL 38
             l+ql+e +G+ d++  +qaL ++n+nle Av++L
   Q: 19   TFLNQLREiTGInDTQILQQALKDSNGNLELAVAFL 54
           569*******************************98 PP
   
Organism Cavia porcellus
Protein Sequence
(Fasta)
MTVEQNVLQQ SAAQKHQQTF LNQLREITGI NDTQILQQAL KDSNGNLELA VAFLTAKNAK 60
SPQQEETTYY QTALPGNDRY ISVGSQADTN VIDLTGDDKD DLQRAIALSL AESNRAFRET 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cpo-021807|DUB,USP;UBD,UBA|Cavia porcellus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGACCGTTG AGCAGAACGT GCTGCAACAG AGCGCGGCAC AGAAGGTGAA GGCCGCCCGT 60
GGCGGCCCCG GGCCTCGGCG CCCGGCTGCG CGTGCGAGCG GGGTGCAGTT TGCGGGGCTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cpo-021807|DUB,USP;UBD,UBA|Cavia porcellus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR003903--UIM_dom
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
PF02809--UIM
SMART

SM00726--UIM
Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1904293--P:negative regulation of ERAD pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001340 Ailuropoda melanoleuca 96.31 0.00e+00 2072.00
IUUC-Apl-004030 Anas platyrhynchos 85.29 0.00e+00 1907.00
IUUC-Aca-004753 Anolis carolinensis 67.78 0.00e+00 1072.00
IUUC-Ani-009503 Aspergillus nidulans 33.02 5.00e-11 63.90
IUUC-Ame-010624 Astyanax mexicanus 74.97 0.00e+00 1169.00
IUUC-Bta-013166 Bos taurus 92.44 0.00e+00 1947.00
IUUC-Cel-018346 Caenorhabditis elegans 26.87 4.00e-28 120.00
IUUC-Cja-019150 Callithrix jacchus 93.24 0.00e+00 2037.00
IUUC-Cfa-020649 Canis familiaris 92.97 0.00e+00 2051.00
IUUC-Csa-023388 Chlorocebus sabaeus 92.88 0.00e+00 2036.00
IUUC-Cho-024343 Choloepus hoffmanni 79.42 0.00e+00 980.00
IUUC-Cin-025302 Ciona intestinalis 37.17 2.00e-95 343.00
IUUC-Dre-028016 Danio rerio 72.57 0.00e+00 1627.00
IUUC-Dno-029495 Dasypus novemcinctus 90.71 0.00e+00 2047.00
IUUC-Dor-030948 Dipodomys ordii 84.24 0.00e+00 1501.00
IUUC-Fca-035876 Felis catus 93.46 0.00e+00 1986.00
IUUC-Fal-036762 Ficedula albicollis 83.62 0.00e+00 1120.00
IUUC-Gmo-039490 Gadus morhua 74.43 0.00e+00 1605.00
IUUC-Gga-040817 Gallus gallus 82.00 0.00e+00 1887.00
IUUC-Gac-042473 Gasterosteus aculeatus 73.64 0.00e+00 1634.00
IUUC-Ggo-044939 Gorilla gorilla 94.76 0.00e+00 2013.00
IUUC-Hsa-046204 Homo sapiens 93.65 0.00e+00 1976.00
IUUC-Kpa-049349 Komagataella pastoris 28.27 2.00e-10 62.00
IUUC-Lch-049572 Latimeria chalumnae 76.68 0.00e+00 1709.00
IUUC-Loc-052070 Lepisosteus oculatus 75.38 0.00e+00 1672.00
IUUC-Lma-053078 Leptosphaeria maculans 30.56 4.00e-12 67.40
IUUC-Laf-054426 Loxodonta africana 93.09 0.00e+00 1835.00
IUUC-Mcc-055858 Macaca mulatta 93.07 0.00e+00 2065.00
IUUC-Mla-058944 Melampsora laricipopulina 23.00 1.00e-10 62.80
IUUC-Mga-059808 Meleagris gallopavo 82.59 0.00e+00 1825.00
IUUC-Mmr-060987 Microcebus murinus 93.32 0.00e+00 2028.00
IUUC-Mmu-064245 Mus musculus 90.43 0.00e+00 1968.00
IUUC-Mpu-066304 Mustela putorius furo 92.18 0.00e+00 2013.00
IUUC-Mlu-067139 Myotis lucifugus 92.62 0.00e+00 2009.00
IUUC-Nle-069075 Nomascus leucogenys 93.65 0.00e+00 1972.00
IUUC-Ont-072150 Oreochromis niloticus 70.84 0.00e+00 1623.00
IUUC-Oan-073054 Ornithorhynchus anatinus 81.49 0.00e+00 1759.00
IUUC-Ocu-074102 Oryctolagus cuniculus 90.71 0.00e+00 2041.00
IUUC-Ola-086529 Oryzias latipes 71.94 0.00e+00 1571.00
IUUC-Oga-088939 Otolemur garnettii 91.93 0.00e+00 1960.00
IUUC-Oar-090266 Ovis aries 92.25 0.00e+00 2004.00
IUUC-Ptr-090546 Pan troglodytes 93.47 0.00e+00 1972.00
IUUC-Pan-092311 Papio anubis 92.98 0.00e+00 2066.00
IUUC-Psi-093459 Pelodiscus sinensis 90.06 0.00e+00 1179.00
IUUC-Pfo-096726 Poecilia formosa 67.04 0.00e+00 1486.00
IUUC-Pab-097608 Pongo abelii 96.36 0.00e+00 2030.00
IUUC-Pca-100718 Procavia capensis 85.35 0.00e+00 1464.00
IUUC-Pva-103150 Pteropus vampyrus 94.67 0.00e+00 1547.00
IUUC-Pyt-104434 Pyrenophora triticirepentis 23.67 1.00e-13 72.40
IUUC-Rno-105727 Rattus norvegicus 90.98 0.00e+00 1934.00
IUUC-Sha-107051 Sarcophilus harrisii 86.55 0.00e+00 1870.00
IUUC-Sar-113097 Sorex araneus 87.30 0.00e+00 1873.00
IUUC-Sre-115145 Sporisorium reilianum 31.73 7.00e-09 57.00
IUUC-Ssc-115877 Sus scrofa 90.50 0.00e+00 1933.00
IUUC-Tgu-117473 Taeniopygia guttata 78.58 0.00e+00 1724.00
IUUC-Tru-118135 Takifugu rubripes 67.34 0.00e+00 1424.00
IUUC-Tsy-119471 Tarsius syrichta 91.09 0.00e+00 1864.00
IUUC-Tni-120139 Tetraodon nigroviridis 64.43 0.00e+00 1306.00
IUUC-Tbe-127549 Tupaia belangeri 89.82 0.00e+00 1895.00
IUUC-Ttr-128896 Tursiops truncatus 91.71 0.00e+00 1969.00
IUUC-Vda-129742 Verticillium dahliae 24.13 1.00e-11 65.90
IUUC-Vpa-130500 Vicugna pacos 89.09 0.00e+00 1890.00
IUUC-Xtr-132896 Xenopus tropicalis 78.74 0.00e+00 1726.00
Created Date 25-Jun-2017

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