iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	miRNAMap	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.50e-13	49.0	825	880

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           ++v++ly  ++ +  eL+++ G +++ +  e+++ gWl+g  +l+gk Gl+P+n+ve l
   Q: 825  RRVKTLYACTPDHHSELSFEPGQIITNV-YESNEDGWLVG--TLNGKTGLIPSNYVEPL 880
           689*************************.9**********..8*************987 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MVLRALEFSD SISDSPWFRQ NLHDHEVALD DAFKNIKLIE NQCKELIACT KKLSTAQRAF 60
AKTLSEFKFE TVGTNQTDDE RFIATCLKEF GSLINQVEDE RMKLVGQAEE SYLEPIKKFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGACACCTT GTCCAGTAGA CAAAACCCGT CTACTTAGGA CTCTGCGCTC ATCACAAATG 60
GTGTTACGGG CGCTCGAGTT TTCGGACTCG ATATCCGATT CTCCGTGGTT TCGACAAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0343--GTPase activation
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain

PROSITE

PS50003--PH_DOMAIN
PS50238--RHOGAP
PS50002--SH3

Pfam

PF00620--RhoGAP
PF14604--SH3_9

SMART

SM00233--PH
SM00324--RhoGAP
SM00326--SH3

Gene Ontology

GO:0005096--F:GTPase activator activity
GO:0007165--P:signal transduction

KEGG

cel:CELE_T04C9.1

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001613	Ailuropoda melanoleuca	43.31	2.00e-130	458.00
IUUC-Apl-003297	Anas platyrhynchos	39.66	2.00e-124	438.00
IUUC-Aca-005285	Anolis carolinensis	41.14	5.00e-135	473.00
IUUC-Ame-011422	Astyanax mexicanus	41.92	8.00e-108	383.00
IUUC-Bta-012379	Bos taurus	41.07	2.00e-128	451.00
IUUC-Cja-019208	Callithrix jacchus	43.31	3.00e-130	457.00
IUUC-Cfa-020928	Canis familiaris	43.31	6.00e-130	457.00
IUUC-Cpo-021338	Cavia porcellus	43.47	2.00e-130	458.00
IUUC-Csa-023570	Chlorocebus sabaeus	43.31	5.00e-130	457.00
IUUC-Cin-025725	Ciona intestinalis	35.17	1.00e-100	359.00
IUUC-Dre-027525	Danio rerio	38.45	7.00e-110	390.00
IUUC-Dno-029143	Dasypus novemcinctus	43.31	2.00e-129	455.00
IUUC-Dor-030697	Dipodomys ordii	43.14	2.00e-129	455.00
IUUC-Dme-032147	Drosophila melanogaster	41.11	6.00e-126	444.00
IUUC-Ete-032645	Echinops telfairi	41.14	3.00e-113	401.00
IUUC-Eca-033791	Equus caballus	43.19	5.00e-130	457.00
IUUC-Eeu-035202	Erinaceus europaeus	43.94	6.00e-43	167.00
IUUC-Fca-036131	Felis catus	42.54	4.00e-125	441.00
IUUC-Fal-037129	Ficedula albicollis	43.65	1.00e-131	462.00
IUUC-Gga-041023	Gallus gallus	42.14	3.00e-127	447.00
IUUC-Gac-041728	Gasterosteus aculeatus	37.56	7.00e-105	373.00
IUUC-Ggo-044863	Gorilla gorilla	43.33	1.00e-129	456.00
IUUC-Hsa-046471	Homo sapiens	43.14	1.00e-129	456.00
IUUC-Itr-049060	Ictidomys tridecemlineatus	43.31	7.00e-130	456.00
IUUC-Lch-050300	Latimeria chalumnae	40.96	4.00e-116	410.00
IUUC-Loc-052782	Lepisosteus oculatus	44.26	3.00e-130	457.00
IUUC-Laf-053585	Loxodonta africana	43.31	7.00e-126	443.00
IUUC-Mcc-055458	Macaca mulatta	43.31	4.00e-130	457.00
IUUC-Meu-056107	Macropus eugenii	36.18	6.00e-93	334.00
IUUC-Mga-059914	Meleagris gallopavo	41.50	4.00e-109	387.00
IUUC-Mmr-060728	Microcebus murinus	42.86	7.00e-119	420.00
IUUC-Mdo-062864	Monodelphis domestica	39.94	2.00e-131	461.00
IUUC-Mmu-063756	Mus musculus	43.14	3.00e-136	478.00
IUUC-Mlu-067375	Myotis lucifugus	39.62	2.00e-118	418.00
IUUC-Nle-069043	Nomascus leucogenys	39.52	3.00e-91	328.00
IUUC-Opr-071168	Ochotona princeps	36.20	4.00e-59	221.00
IUUC-Ont-071443	Oreochromis niloticus	39.55	4.00e-121	427.00
IUUC-Oan-072978	Ornithorhynchus anatinus	39.66	4.00e-106	377.00
IUUC-Ocu-073915	Oryctolagus cuniculus	42.58	7.00e-130	456.00
IUUC-Ola-086319	Oryzias latipes	40.67	1.00e-117	416.00
IUUC-Oga-088922	Otolemur garnettii	49.76	4.00e-54	203.00
IUUC-Oar-089349	Ovis aries	43.62	4.00e-130	457.00
IUUC-Ptr-091027	Pan troglodytes	43.31	8.00e-130	456.00
IUUC-Pan-092791	Papio anubis	43.31	5.00e-130	457.00
IUUC-Psi-093144	Pelodiscus sinensis	42.59	6.00e-131	460.00
IUUC-Pma-094731	Petromyzon marinus	28.90	3.00e-18	87.00
IUUC-Pfo-097265	Poecilia formosa	38.85	1.00e-115	409.00
IUUC-Pab-097783	Pongo abelii	43.31	5.00e-130	457.00
IUUC-Pva-102980	Pteropus vampyrus	43.14	1.00e-129	456.00
IUUC-Rno-105142	Rattus norvegicus	43.14	1.00e-136	478.00
IUUC-Sha-107213	Sarcophilus harrisii	42.57	3.00e-118	417.00
IUUC-Ssc-115511	Sus scrofa	47.78	2.00e-70	258.00
IUUC-Tgu-117458	Taeniopygia guttata	40.22	2.00e-132	465.00
IUUC-Tru-117767	Takifugu rubripes	42.31	6.00e-126	443.00
IUUC-Tsy-119150	Tarsius syrichta	41.58	2.00e-118	418.00
IUUC-Tni-119893	Tetraodon nigroviridis	41.03	3.00e-86	311.00
IUUC-Tbe-128126	Tupaia belangeri	26.37	9.00e-07	47.80
IUUC-Ttr-129045	Tursiops truncatus	37.48	4.00e-108	384.00
IUUC-Xtr-131767	Xenopus tropicalis	42.81	2.00e-127	448.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence