iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-072997

Ensembl Protein ID

ENSOANP00000008375.3

UniProt Accession

F6VI70; F6VI70_ORNAN

Protein Name

Tyrosine-protein kinase

Gene Name

YES1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000005265.3	ENSOANT00000008377.3	ENSOANP00000008375.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.80e-15	54.5	17	72

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydyea ++++L++kkG+  ++i  ++++++W+++ + ++gk G +P+n+v+ ++
   Q: 17   FVALYDYEARTTEDLSFKKGERFQII--NNTEGDWWEARSIATGKTGYIPSNYVAPAD 72
           789***********************..8999**********************9875 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MLCVVFFSPF SGGVTIFVAL YDYEARTTED LSFKKGERFQ IINNTEGDWW EARSIATGKT 60
GYIPSNYVAP ADSIQAEEWY FGKMGRKDAE RLLLSPGNQR GIFLVRESET TKGAYSLSIR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTAATCCCT TTACACGTGT GCTGATGCTT TGTGTGGTTT TTTTTTCCCC TTTCTCAGGT 60
GGTGTTACTA TATTTGTGGC CTTATATGAT TATGAAGCTC GAACTACAGA AGATCTTTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005884--C:actin filament
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0036120--P:cellular response to platelet-derived growth factor stimulus
GO:0071300--P:cellular response to retinoic acid
GO:0071560--P:cellular response to transforming growth factor beta stimulus
GO:0015758--P:glucose transport
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

KEGG

oaa:100076997

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002374	Ailuropoda melanoleuca	97.37	0.00e+00	931.00
IUUC-Apl-004032	Anas platyrhynchos	98.25	0.00e+00	940.00
IUUC-Aca-004255	Anolis carolinensis	97.59	0.00e+00	938.00
IUUC-Ath-007146	Arabidopsis thaliana	33.68	2.00e-22	100.00
IUUC-Ame-010954	Astyanax mexicanus	93.91	0.00e+00	910.00
IUUC-Bta-013503	Bos taurus	97.58	0.00e+00	931.00
IUUC-Bol-016049	Brassica oleracea	32.95	2.00e-17	84.30
IUUC-Bra-017486	Brassica rapa	32.12	6.00e-21	95.50
IUUC-Cja-019694	Callithrix jacchus	97.36	0.00e+00	931.00
IUUC-Cfa-020402	Canis familiaris	97.58	0.00e+00	935.00
IUUC-Cpo-022506	Cavia porcellus	97.36	0.00e+00	932.00
IUUC-Csa-023713	Chlorocebus sabaeus	97.58	0.00e+00	933.00
IUUC-Cin-025390	Ciona intestinalis	71.40	0.00e+00	660.00
IUUC-Csv-026029	Ciona savignyi	72.03	1.00e-180	625.00
IUUC-Dre-027978	Danio rerio	94.39	0.00e+00	891.00
IUUC-Dno-029651	Dasypus novemcinctus	80.34	0.00e+00	807.00
IUUC-Dor-030202	Dipodomys ordii	96.46	0.00e+00	916.00
IUUC-Ete-033170	Echinops telfairi	81.00	0.00e+00	783.00
IUUC-Eca-034157	Equus caballus	97.14	0.00e+00	930.00
IUUC-Eeu-034950	Erinaceus europaeus	96.24	3.00e-156	543.00
IUUC-Fca-036233	Felis catus	97.58	0.00e+00	936.00
IUUC-Fal-037461	Ficedula albicollis	98.25	0.00e+00	943.00
IUUC-Gmo-038929	Gadus morhua	92.60	0.00e+00	869.00
IUUC-Gga-041107	Gallus gallus	98.03	0.00e+00	938.00
IUUC-Gac-042321	Gasterosteus aculeatus	92.97	0.00e+00	894.00
IUUC-Hsa-047010	Homo sapiens	97.36	0.00e+00	932.00
IUUC-Itr-049014	Ictidomys tridecemlineatus	82.68	0.00e+00	819.00
IUUC-Lch-050239	Latimeria chalumnae	96.26	0.00e+00	921.00
IUUC-Lpe-051166	Leersia perrieri	34.74	6.00e-24	105.00
IUUC-Loc-052314	Lepisosteus oculatus	94.52	0.00e+00	871.00
IUUC-Laf-053517	Loxodonta africana	97.80	0.00e+00	937.00
IUUC-Mcc-055626	Macaca mulatta	97.58	0.00e+00	933.00
IUUC-Mtr-058733	Medicago truncatula	32.73	7.00e-23	102.00
IUUC-Mga-059310	Meleagris gallopavo	98.03	0.00e+00	938.00
IUUC-Mmr-061652	Microcebus murinus	97.14	0.00e+00	930.00
IUUC-Mdo-062963	Monodelphis domestica	97.14	0.00e+00	929.00
IUUC-Mmu-064128	Mus musculus	97.14	0.00e+00	932.00
IUUC-Mpu-065906	Mustela putorius furo	97.58	0.00e+00	935.00
IUUC-Mlu-067035	Myotis lucifugus	96.94	0.00e+00	929.00
IUUC-Nle-069041	Nomascus leucogenys	92.53	0.00e+00	873.00
IUUC-Opr-070299	Ochotona princeps	87.69	0.00e+00	825.00
IUUC-Ont-072337	Oreochromis niloticus	94.34	0.00e+00	908.00
IUUC-Ocu-074171	Oryctolagus cuniculus	97.58	0.00e+00	935.00
IUUC-Oba-075994	Oryza barthii	34.27	7.00e-22	98.60
IUUC-Ogl-077331	Oryza glaberrima	34.74	4.00e-24	106.00
IUUC-Ogu-078962	Oryza glumaepatula	34.74	3.00e-24	106.00
IUUC-Oin-079172	Oryza indica	34.74	4.00e-24	106.00
IUUC-Olo-080286	Oryza longistaminata	34.74	4.00e-24	106.00
IUUC-Ome-081400	Oryza meridionalis	34.74	3.00e-24	106.00
IUUC-Oru-084741	Oryza rufipogon	34.74	3.00e-24	106.00
IUUC-Osa-085779	Oryza sativa	34.74	4.00e-24	106.00
IUUC-Ola-086619	Oryzias latipes	90.71	0.00e+00	894.00
IUUC-Oga-087957	Otolemur garnettii	97.14	0.00e+00	931.00
IUUC-Oar-089670	Ovis aries	97.58	0.00e+00	932.00
IUUC-Ptr-091352	Pan troglodytes	97.36	0.00e+00	933.00
IUUC-Pan-092202	Papio anubis	97.58	0.00e+00	933.00
IUUC-Psi-093310	Pelodiscus sinensis	98.24	0.00e+00	939.00
IUUC-Pma-094232	Petromyzon marinus	87.04	0.00e+00	857.00
IUUC-Pfo-096137	Poecilia formosa	91.07	0.00e+00	886.00
IUUC-Pab-098301	Pongo abelii	97.58	0.00e+00	931.00
IUUC-Ppe-102072	Prunus persica	37.69	1.00e-25	111.00
IUUC-Pva-102592	Pteropus vampyrus	93.19	0.00e+00	883.00
IUUC-Rno-105544	Rattus norvegicus	96.94	0.00e+00	929.00
IUUC-Sha-107539	Sarcophilus harrisii	83.55	0.00e+00	821.00
IUUC-Sly-111528	Solanum lycopersicum	33.17	3.00e-22	100.00
IUUC-Stu-112831	Solanum tuberosum	32.66	1.00e-21	97.80
IUUC-Sar-113364	Sorex araneus	93.63	0.00e+00	890.00
IUUC-Ssc-115762	Sus scrofa	82.68	0.00e+00	819.00
IUUC-Tgu-117380	Taeniopygia guttata	98.25	0.00e+00	943.00
IUUC-Tru-117594	Takifugu rubripes	92.59	0.00e+00	901.00
IUUC-Tni-120433	Tetraodon nigroviridis	92.17	0.00e+00	885.00
IUUC-Tae-123414	Triticum aestivum	30.91	3.00e-19	90.10
IUUC-Ttr-128893	Tursiops truncatus	97.14	0.00e+00	931.00
IUUC-Vpa-130060	Vicugna pacos	97.58	0.00e+00	933.00
IUUC-Xtr-132322	Xenopus tropicalis	97.14	0.00e+00	930.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence