• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Details
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046729
UUCD1 version UUC-HoS-00781
Ensembl Protein ID ENSP00000322242.4
UniProt Accession Q8N5U6; Q92550; Q9NPP8; Q9ULW4; RNF10_HUMAN
Genbank Protein ID BAA84708.1; BAA13392.2; AAP35620.1; AAH16622.1; AAH31596.1; AAI01710.1; AAI01716.1; CAB97533.1
Protein Name RING finger protein 10
Genbank Nucleotide ID AB027196; D87451; BT006974; BC016622; BC031596; BC101709; BC101715; AL389976
Gene Name RNF10; KIAA0262; RIE2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000022840.15 ENST00000325954.8 ENSP00000322242.4
ENSG00000022840.15 ENST00000542438.1 ENSP00000444770.1
ENSG00000022840.15 ENST00000538796.5 ENSP00000443000.1
ENSG00000022840.15 ENST00000413266.6 ENSP00000415682.2
ENSG00000022840.15 ENST00000536869.5 ENSP00000443790.1
ENSG00000022840.15 ENST00000537997.1 ENSP00000443235.1
ENSG00000022840.15 ENST00000542207.5 ENSP00000439510.1
ENSG00000022840.15 ENST00000537740.1 ENSP00000437392.1
ENSG00000022840.15 ENST00000540046.5 ENSP00000439859.1
ENSG00000022840.15 ENST00000545419.5 ENSP00000445160.1
ENSG00000022840.15 ENST00000538254.1 ENSP00000441487.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
TargetScanRepTarmiRNAMapSomamiR
miRcodeRAID2
Protein-protein Interaction
IIDPINAHINTMentha
InWeb_IM
Disease-associated Information
GWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
UniProtBioGRIDmUbiSiDa
DNA Methylation
MethyCancerTCGAICGC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 activity/RING/RING RING 24105792
Classification
Family E-value Score Start End
E3 activity/RING/RING 2.20e-06 29.7 225 266
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           C+iCl+++    ++++CgH+f+  C+ ++  l+ s+++  +CP+C
   Q: 225  CPICLYPPTA-AKITRCGHIFCWACILHY--LSLSEKTWSKCPIC 266
           ********99.99*************999..5545666669**** PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Transcriptional factor involved in the regulation of MAG (Myelin-associated glycoprotein) expression. Acts as a regulator of Schwann cell differentiation and myelination.
 Transcriptional factor involved in the regulation of MAG (Myelin-associated glycoprotein) expression. Acts as a regulator of Schwann cell differentiation and myelination.
Protein Sequence
(Fasta)
MPLSSPNAAA TASDMDKNSG SNSSSASSGS SKGQQPPRSA SAGPAGESKP KSDGKNSSGS 60
KRYNRKRELS YPKNESFNNQ SRRSSSQKSK TFNKMPPQRG GGSSKLFSSS FNGGRRDEVA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046729|E3,RING|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATTACACGCA TGAAACACTG CTTATGGCCT GTTTCCGCCT CTGTCTCCTG GGTAATGGGG 60
ACCACAGGTG CGCACCGCCA CGCCAGGCTA AAGAAATAAA GTGATGTACT GTATGAAGAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046729|E3,RING|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF13639--zf-RING_2
SMART

SM00184--RING
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0044212--F:transcription regulatory region DNA binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0010626--P:negative regulation of Schwann cell proliferation
GO:0031643--P:positive regulation of myelination
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0051865--P:protein autoubiquitination
GO:0006351--P:transcription, DNA-templated
KEGG hsa:9921
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000074 Aegilops tauschii 37.36 4.00e-34 139.00
IUUC-Aml-002043 Ailuropoda melanoleuca 91.95 0.00e+00 981.00
IUUC-Atr-003135 Amborella trichopoda 36.67 6.00e-30 126.00
IUUC-Apl-003850 Anas platyrhynchos 71.86 0.00e+00 799.00
IUUC-Aca-005315 Anolis carolinensis 70.47 0.00e+00 964.00
IUUC-Aly-005597 Arabidopsis lyrata 29.16 4.00e-44 173.00
IUUC-Ago-007969 Ashbya gossypii 28.11 9.00e-14 72.40
IUUC-Acl-008291 Aspergillus clavatus 34.04 3.00e-25 110.00
IUUC-Afl-008511 Aspergillus flavus 27.12 2.00e-40 160.00
IUUC-Afu-008924 Aspergillus fumigatus 31.38 5.00e-24 106.00
IUUC-Ani-009492 Aspergillus nidulans 24.95 7.00e-31 129.00
IUUC-Ang-009588 Aspergillus niger 32.45 2.00e-25 110.00
IUUC-Aor-010006 Aspergillus oryzae 27.12 1.00e-40 161.00
IUUC-Ate-010373 Aspergillus terreus 25.10 1.00e-32 135.00
IUUC-Ame-011589 Astyanax mexicanus 58.04 0.00e+00 712.00
IUUC-Bgr-012151 Blumeria graminis 31.82 2.00e-21 97.40
IUUC-Bta-012512 Bos taurus 93.71 0.00e+00 1299.00
IUUC-Bci-013967 Botrytis cinerea 26.61 3.00e-23 103.00
IUUC-Bdi-014819 Brachypodium distachyon 29.03 5.00e-51 196.00
IUUC-Bol-015780 Brassica oleracea 28.38 4.00e-44 173.00
IUUC-Bra-016966 Brassica rapa 36.69 4.00e-27 116.00
IUUC-Cja-019028 Callithrix jacchus 92.09 0.00e+00 1333.00
IUUC-Cfa-021190 Canis familiaris 92.28 0.00e+00 1277.00
IUUC-Cpo-021765 Cavia porcellus 93.96 0.00e+00 1338.00
IUUC-Cre-022687 Chlamydomonas reinhardtii 32.03 8.00e-10 58.20
IUUC-Csa-023675 Chlorocebus sabaeus 98.95 0.00e+00 1309.00
IUUC-Cho-024480 Choloepus hoffmanni 94.57 0.00e+00 1029.00
IUUC-Cin-025421 Ciona intestinalis 35.91 1.00e-50 194.00
IUUC-Csv-026061 Ciona savignyi 37.52 1.00e-92 334.00
IUUC-Cgl-026594 Colletotrichum gloeosporioides 25.81 1.00e-26 114.00
IUUC-Cne-026993 Cryptococcus neoformans 33.99 7.00e-18 86.30
IUUC-Dre-027622 Danio rerio 55.63 0.00e+00 695.00
IUUC-Dno-029504 Dasypus novemcinctus 92.44 0.00e+00 1267.00
IUUC-Dor-030517 Dipodomys ordii 94.73 0.00e+00 1055.00
IUUC-Dse-031271 Dothistroma septosporum 28.82 1.00e-22 101.00
IUUC-Dme-031728 Drosophila melanogaster 35.71 2.00e-48 187.00
IUUC-Ete-032954 Echinops telfairi 62.97 3.00e-108 385.00
IUUC-Eca-033210 Equus caballus 94.46 0.00e+00 1373.00
IUUC-Eeu-034741 Erinaceus europaeus 83.14 0.00e+00 726.00
IUUC-Fca-035704 Felis catus 92.36 0.00e+00 1278.00
IUUC-Fal-037450 Ficedula albicollis 72.22 0.00e+00 926.00
IUUC-Fox-037977 Fusarium oxysporum 28.90 8.00e-26 112.00
IUUC-Fso-038372 Fusarium solani 28.67 2.00e-27 117.00
IUUC-Gmo-038682 Gadus morhua 54.71 0.00e+00 701.00
IUUC-Ggr-039911 Gaeumannomyces graminis 27.02 8.00e-25 108.00
IUUC-Gga-040648 Gallus gallus 73.06 0.00e+00 943.00
IUUC-Gac-042056 Gasterosteus aculeatus 54.55 0.00e+00 654.00
IUUC-Gma-043144 Glycine max 34.39 2.00e-27 117.00
IUUC-Ggo-045420 Gorilla gorilla 99.87 0.00e+00 1397.00
IUUC-Hvu-047535 Hordeum vulgare 37.36 2.00e-34 140.00
IUUC-Itr-048580 Ictidomys tridecemlineatus 93.49 0.00e+00 1264.00
IUUC-Kpa-049131 Komagataella pastoris 27.07 6.00e-13 69.30
IUUC-Lch-050373 Latimeria chalumnae 66.84 0.00e+00 904.00
IUUC-Lpe-051155 Leersia perrieri 28.31 4.00e-52 199.00
IUUC-Loc-052182 Lepisosteus oculatus 58.61 0.00e+00 745.00
IUUC-Lma-053242 Leptosphaeria maculans 26.76 8.00e-24 106.00
IUUC-Laf-054048 Loxodonta africana 93.82 0.00e+00 1263.00
IUUC-Mcc-055802 Macaca mulatta 98.28 0.00e+00 1372.00
IUUC-Meu-056641 Macropus eugenii 63.33 4.00e-106 379.00
IUUC-Mor-057233 Magnaporthe oryzae 27.84 2.00e-25 110.00
IUUC-Mtr-057767 Medicago truncatula 30.62 8.00e-51 195.00
IUUC-Mla-058967 Melampsora laricipopulina 28.01 3.00e-37 150.00
IUUC-Mga-059783 Meleagris gallopavo 72.64 0.00e+00 970.00
IUUC-Mvi-060430 Microbotryum violaceum 38.64 4.00e-28 120.00
IUUC-Mmr-060953 Microcebus murinus 95.44 0.00e+00 1309.00
IUUC-Mdo-063070 Monodelphis domestica 78.02 0.00e+00 1056.00
IUUC-Mmu-064077 Mus musculus 90.39 0.00e+00 1180.00
IUUC-Mac-065163 Musa acuminata 30.98 5.00e-51 196.00
IUUC-Mpu-066698 Mustela putorius furo 92.85 0.00e+00 1282.00
IUUC-Mlu-067126 Myotis lucifugus 91.12 0.00e+00 1268.00
IUUC-Nfi-068605 Neosartorya fischeri 31.91 2.00e-24 107.00
IUUC-Ncr-068754 Neurospora crassa 31.17 1.00e-20 95.10
IUUC-Nle-070138 Nomascus leucogenys 99.37 0.00e+00 1371.00
IUUC-Opr-070959 Ochotona princeps 86.08 0.00e+00 1174.00
IUUC-Ont-072344 Oreochromis niloticus 55.60 0.00e+00 665.00
IUUC-Oan-073664 Ornithorhynchus anatinus 83.33 8.00e-169 587.00
IUUC-Ocu-074463 Oryctolagus cuniculus 86.60 0.00e+00 1113.00
IUUC-Oba-075523 Oryza barthii 33.80 9.00e-34 139.00
IUUC-Obr-076032 Oryza brachyantha 32.20 5.00e-33 136.00
IUUC-Ogl-077231 Oryza glaberrima 33.80 2.00e-33 137.00
IUUC-Ogu-078117 Oryza glumaepatula 29.12 3.00e-55 210.00
IUUC-Oin-079998 Oryza indica 33.33 6.00e-33 135.00
IUUC-Olo-080870 Oryza longistaminata 33.80 5.00e-33 136.00
IUUC-Ome-081402 Oryza meridionalis 32.51 1.00e-33 138.00
IUUC-Oni-082566 Oryza nivara 33.80 1.00e-33 138.00
IUUC-Opu-083226 Oryza punctata 33.80 3.00e-33 137.00
IUUC-Oru-084192 Oryza rufipogon 33.33 3.00e-33 137.00
IUUC-Osa-086156 Oryza sativa 31.69 1.00e-33 138.00
IUUC-Ola-086980 Oryzias latipes 56.54 0.00e+00 680.00
IUUC-Olu-087613 Ostreococcus lucimarinus 30.41 3.00e-18 87.00
IUUC-Oga-088829 Otolemur garnettii 91.45 0.00e+00 1248.00
IUUC-Oar-089979 Ovis aries 93.43 0.00e+00 1251.00
IUUC-Ptr-091080 Pan troglodytes 99.63 0.00e+00 1416.00
IUUC-Pan-092604 Papio anubis 98.77 0.00e+00 1377.00
IUUC-Psi-093248 Pelodiscus sinensis 73.92 0.00e+00 990.00
IUUC-Pma-094260 Petromyzon marinus 48.06 1.00e-57 218.00
IUUC-Pno-095113 Phaeosphaeria nodorum 25.71 5.00e-24 106.00
IUUC-Pfo-097012 Poecilia formosa 55.22 0.00e+00 627.00
IUUC-Pab-098745 Pongo abelii 99.66 0.00e+00 1089.00
IUUC-Pop-099889 Populus trichocarpa 36.05 5.00e-28 119.00
IUUC-Pca-100895 Procavia capensis 85.08 0.00e+00 1144.00
IUUC-Pva-102617 Pteropus vampyrus 94.35 0.00e+00 1285.00
IUUC-Pgr-103385 Puccinia graminis 29.38 1.00e-39 158.00
IUUC-Ptt-103845 Puccinia triticina 29.09 2.00e-39 157.00
IUUC-Pte-104025 Pyrenophora teres 26.26 5.00e-24 106.00
IUUC-Pyt-104699 Pyrenophora triticirepentis 25.90 6.00e-23 102.00
IUUC-Rno-105232 Rattus norvegicus 90.38 0.00e+00 1277.00
IUUC-Sce-106225 Saccharomyces cerevisiae 26.04 7.00e-12 65.90
IUUC-Sha-106788 Sarcophilus harrisii 78.98 0.00e+00 1023.00
IUUC-Spo-108070 Schizosaccharomyces pombe 33.33 4.00e-29 123.00
IUUC-Ssl-108567 Sclerotinia sclerotiorum 26.61 2.00e-21 98.20
IUUC-Sly-110950 Solanum lycopersicum 39.09 3.00e-19 90.10
IUUC-Sar-113085 Sorex araneus 88.65 0.00e+00 1116.00
IUUC-Sbi-114553 Sorghum bicolor 38.01 1.00e-33 138.00
IUUC-Sre-115103 Sporisorium reilianum 39.86 5.00e-29 123.00
IUUC-Ssc-115675 Sus scrofa 94.63 0.00e+00 963.00
IUUC-Tgu-116506 Taeniopygia guttata 68.58 0.00e+00 925.00
IUUC-Tru-118158 Takifugu rubripes 56.09 0.00e+00 660.00
IUUC-Tsy-119477 Tarsius syrichta 87.50 0.00e+00 1134.00
IUUC-Tni-120482 Tetraodon nigroviridis 51.74 0.00e+00 647.00
IUUC-Tca-120997 Theobroma cacao 31.22 3.00e-52 199.00
IUUC-Tre-121948 Trichoderma reesei 32.87 4.00e-27 116.00
IUUC-Tvi-122648 Trichoderma virens 31.63 5.00e-26 112.00
IUUC-Tae-124316 Triticum aestivum 37.14 1.00e-34 141.00
IUUC-Tme-127224 Tuber melanosporum 25.75 3.00e-20 94.00
IUUC-Tbe-128091 Tupaia belangeri 92.05 3.00e-176 612.00
IUUC-Ttr-128830 Tursiops truncatus 85.82 0.00e+00 1174.00
IUUC-Uma-129360 Ustilago maydis 40.00 2.00e-28 121.00
IUUC-Vda-129856 Verticillium dahliae 34.46 7.00e-21 95.90
IUUC-Vpa-130094 Vicugna pacos 94.63 0.00e+00 992.00
IUUC-Vvi-131165 Vitis vinifera 37.42 2.00e-25 111.00
IUUC-Xtr-132916 Xenopus tropicalis 60.88 0.00e+00 802.00
IUUC-Xma-134009 Xiphophorus maculatus 67.26 3.00e-75 275.00
IUUC-Yli-134346 Yarrowia lipolytica 27.13 4.00e-13 69.70
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved