iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117547

UUCD1 version

UUC-TaR-00278

Ensembl Protein ID

ENSTRUP00000028734.1

UniProt Accession

H2TVM5; H2TVM5_TAKRU

Protein Name

Uncharacterized protein

Gene Name

rnf19a (1 of many); rnf19a

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000011384.1	ENSTRUT00000028850.1	ENSTRUP00000028734.1
ENSTRUG00000011384.1	ENSTRUT00000028851.1	ENSTRUP00000028735.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	6.80e-50	170.3	107	307

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++Cll++s e+++ +++C+h+ C +Cl+qyl+++i+e++ ++iscp  ec+e++++++i  +l ++ l+++ye+++l++++ ad++++w
   Q: 107  CPLCLLHHSRESFPDIMTCHHRSCIDCLRQYLRIEISESR-VNISCP--ECSERFNPHDICIILGDRALMDKYEEFMLRRWLVADPDCRW 193
           ****************************************.9*****..89*************************************** PP
   S: 91   cpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeek.......eeaeskelleanskkCpkCkvyi 171
           cpapdC ++v++  +a  +k ++ +++cg+efC++Ck+ wH++++C+++++++a++ + +       ++++++ ++++++k+Cp+C +yi
   Q: 194  CPAPDCGYAVIAFGCAscPKITCGRDGCGTEFCYHCKQLWHPNQTCDAARQQRAQSLRLRtvrssslSHSQESGAAADDIKPCPRCAAYI 283
           *************99988999999*******************************99988999**99999999***************** PP
   S: 172  ek..negCnhmtCakCkaefCwlC 193
           +k  +++CnhmtCa C++efCwlC
   Q: 284  IKmnDGSCNHMTCAVCGCEFCWLC 307
           *997889***************** PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MGSDRDLQST ASSISLPSVK KAPKKRRLSL ASFFRRRTRE HKSGRQRSRE LQHPGPGGLG 60
GVDGIASIES IHSEMCNDKN SAFFWASSST SSSTKVGGGA GPELLECPLC LLHHSRESFP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATAACATAA GCAAACATAA TCAGTTGAGT TTTGTTCAAA CTGATATACA GTCAACAGTT 60
ATTAAATGTC CAAAGTTGTG TCAGTAGTTT GTTGGACAGG TTAGGCCCTT ATGTGTTGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR

Gene Ontology

GO:0005813--C:centrosome
GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001958	Ailuropoda melanoleuca	79.74	0.00e+00	932.00
IUUC-Apl-003427	Anas platyrhynchos	80.00	0.00e+00	907.00
IUUC-Aca-004252	Anolis carolinensis	79.87	0.00e+00	900.00
IUUC-Ame-011434	Astyanax mexicanus	86.09	0.00e+00	801.00
IUUC-Bta-013558	Bos taurus	79.87	0.00e+00	935.00
IUUC-Cel-018626	Caenorhabditis elegans	55.11	3.00e-106	380.00
IUUC-Cja-019070	Callithrix jacchus	80.39	0.00e+00	939.00
IUUC-Cfa-020286	Canis familiaris	79.74	0.00e+00	930.00
IUUC-Cpo-022015	Cavia porcellus	79.45	0.00e+00	938.00
IUUC-Csa-023975	Chlorocebus sabaeus	78.26	0.00e+00	925.00
IUUC-Cho-024442	Choloepus hoffmanni	66.10	0.00e+00	748.00
IUUC-Dre-028422	Danio rerio	78.52	0.00e+00	841.00
IUUC-Dno-029018	Dasypus novemcinctus	78.98	0.00e+00	914.00
IUUC-Dor-030548	Dipodomys ordii	76.79	5.00e-121	428.00
IUUC-Eca-034249	Equus caballus	80.00	0.00e+00	936.00
IUUC-Eeu-035298	Erinaceus europaeus	81.98	2.00e-180	626.00
IUUC-Fca-035912	Felis catus	79.61	0.00e+00	931.00
IUUC-Fal-037488	Ficedula albicollis	78.29	0.00e+00	879.00
IUUC-Gmo-038893	Gadus morhua	87.93	0.00e+00	834.00
IUUC-Gga-040380	Gallus gallus	79.34	0.00e+00	893.00
IUUC-Gac-041421	Gasterosteus aculeatus	86.03	0.00e+00	968.00
IUUC-Ggo-044893	Gorilla gorilla	79.58	0.00e+00	941.00
IUUC-Hsa-046876	Homo sapiens	79.58	0.00e+00	941.00
IUUC-Itr-048257	Ictidomys tridecemlineatus	79.32	0.00e+00	936.00
IUUC-Lch-049774	Latimeria chalumnae	79.87	0.00e+00	930.00
IUUC-Loc-052040	Lepisosteus oculatus	80.31	0.00e+00	956.00
IUUC-Laf-053874	Loxodonta africana	78.95	0.00e+00	920.00
IUUC-Mcc-054817	Macaca mulatta	65.00	1.00e-54	205.00
IUUC-Mga-060175	Meleagris gallopavo	80.00	0.00e+00	907.00
IUUC-Mmr-060800	Microcebus murinus	79.32	0.00e+00	937.00
IUUC-Mdo-061827	Monodelphis domestica	79.74	0.00e+00	875.00
IUUC-Mmu-064134	Mus musculus	78.27	0.00e+00	904.00
IUUC-Mpu-066076	Mustela putorius furo	79.74	0.00e+00	927.00
IUUC-Mlu-068218	Myotis lucifugus	79.08	0.00e+00	914.00
IUUC-Nle-069707	Nomascus leucogenys	84.13	0.00e+00	832.00
IUUC-Opr-070977	Ochotona princeps	79.47	0.00e+00	949.00
IUUC-Ont-072373	Oreochromis niloticus	90.00	0.00e+00	1021.00
IUUC-Oan-073376	Ornithorhynchus anatinus	91.67	9.00e-147	513.00
IUUC-Ocu-074878	Oryctolagus cuniculus	79.74	0.00e+00	920.00
IUUC-Ola-086472	Oryzias latipes	85.96	0.00e+00	989.00
IUUC-Oga-088377	Otolemur garnettii	78.93	0.00e+00	937.00
IUUC-Oar-089540	Ovis aries	79.47	0.00e+00	929.00
IUUC-Ptr-090613	Pan troglodytes	79.58	0.00e+00	941.00
IUUC-Pan-092879	Papio anubis	78.53	0.00e+00	925.00
IUUC-Psi-093201	Pelodiscus sinensis	79.87	0.00e+00	904.00
IUUC-Pma-094620	Petromyzon marinus	66.20	0.00e+00	759.00
IUUC-Pfo-096615	Poecilia formosa	89.60	0.00e+00	913.00
IUUC-Pca-100625	Procavia capensis	78.82	0.00e+00	913.00
IUUC-Rno-105998	Rattus norvegicus	79.08	0.00e+00	902.00
IUUC-Sha-107523	Sarcophilus harrisii	81.90	0.00e+00	874.00
IUUC-Sar-113089	Sorex araneus	80.00	0.00e+00	726.00
IUUC-Ssc-115471	Sus scrofa	77.36	0.00e+00	913.00
IUUC-Tgu-117080	Taeniopygia guttata	78.95	0.00e+00	897.00
IUUC-Tsy-119143	Tarsius syrichta	78.82	0.00e+00	924.00
IUUC-Tni-119693	Tetraodon nigroviridis	96.19	0.00e+00	1035.00
IUUC-Ttr-129175	Tursiops truncatus	78.95	0.00e+00	919.00
IUUC-Vpa-130594	Vicugna pacos	73.32	0.00e+00	855.00
IUUC-Xtr-132579	Xenopus tropicalis	78.43	0.00e+00	957.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence