iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xtr-132396

Ensembl Protein ID

ENSXETP00000005271.3

UniProt Accession

F7A415; F7A415_XENTR

Genbank Protein ID

ENSXETP00000005271

Protein Name

Mitogen-activated protein kinase kinase kinase 5

Genbank Nucleotide ID

AAMC01055502

Gene Name

map3k5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000002476.3	ENSXETT00000005271.3	ENSXETP00000005271.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	75.67	0.00e+00	1979.00	IUUC-Hsa-046906

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MQVMSDSSEG ISFSVPCSRL PGSSCCAHED TGGLTLQENA TICGGTRIPE AGSFWREDYL 60
RASAVGSGKD APCYGKWVNP PPTASGGISL RRITVVYVIN EVSPELHACE AAALYSLQEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAAGTAA TGAGTGACAG CAGCGAAGGA ATCAGTTTCT CTGTACCATG CTCACGGCTG 60
CCTGGCTCAA GCTGCTGTGC TCATGAAGAC ACAGGAGGGC TTACGCTACA GGAAAATGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR025136--DUF4071
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR013761--SAM/pointed
IPR008271--Ser/Thr_kinase_AS
IPR011990--TPR-like_helical_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF13281--DUF4071
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005622--C:intracellular
GO:0005524--F:ATP binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0000186--P:activation of MAPKK activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002318	Ailuropoda melanoleuca	78.99	0.00e+00	1889.00
IUUC-Apl-003713	Anas platyrhynchos	79.97	0.00e+00	1801.00
IUUC-Aca-005331	Anolis carolinensis	78.53	0.00e+00	1811.00
IUUC-Ame-011158	Astyanax mexicanus	68.48	0.00e+00	1714.00
IUUC-Bta-012770	Bos taurus	79.27	0.00e+00	1968.00
IUUC-Cja-019656	Callithrix jacchus	75.14	0.00e+00	1955.00
IUUC-Cfa-020488	Canis familiaris	78.94	0.00e+00	1964.00
IUUC-Cpo-022516	Cavia porcellus	77.84	0.00e+00	1875.00
IUUC-Csa-023104	Chlorocebus sabaeus	79.33	0.00e+00	1886.00
IUUC-Cho-024379	Choloepus hoffmanni	75.96	0.00e+00	1038.00
IUUC-Dre-028836	Danio rerio	69.55	0.00e+00	1728.00
IUUC-Dno-029842	Dasypus novemcinctus	77.86	0.00e+00	1831.00
IUUC-Dor-030990	Dipodomys ordii	81.12	0.00e+00	1677.00
IUUC-Ete-032693	Echinops telfairi	69.40	0.00e+00	1596.00
IUUC-Eca-033337	Equus caballus	78.91	0.00e+00	1913.00
IUUC-Eeu-034602	Erinaceus europaeus	67.82	0.00e+00	1418.00
IUUC-Fca-035954	Felis catus	78.67	0.00e+00	1582.00
IUUC-Fal-037358	Ficedula albicollis	78.70	0.00e+00	1829.00
IUUC-Gmo-038836	Gadus morhua	72.98	0.00e+00	1637.00
IUUC-Gga-040443	Gallus gallus	79.41	0.00e+00	1934.00
IUUC-Gac-041634	Gasterosteus aculeatus	69.68	0.00e+00	1765.00
IUUC-Ggo-045263	Gorilla gorilla	73.72	0.00e+00	1893.00
IUUC-Hsa-046906	Homo sapiens	75.67	0.00e+00	1970.00
IUUC-Itr-048449	Ictidomys tridecemlineatus	76.68	0.00e+00	868.00
IUUC-Lch-050213	Latimeria chalumnae	73.51	0.00e+00	1628.00
IUUC-Loc-051829	Lepisosteus oculatus	67.53	0.00e+00	1728.00
IUUC-Laf-053538	Loxodonta africana	75.00	0.00e+00	1958.00
IUUC-Mcc-054776	Macaca mulatta	75.67	0.00e+00	1976.00
IUUC-Mga-059636	Meleagris gallopavo	79.82	0.00e+00	1868.00
IUUC-Mmr-061323	Microcebus murinus	75.90	0.00e+00	1934.00
IUUC-Mdo-062146	Monodelphis domestica	79.72	0.00e+00	1920.00
IUUC-Mmu-064022	Mus musculus	78.44	0.00e+00	1935.00
IUUC-Mpu-066531	Mustela putorius furo	74.11	0.00e+00	1965.00
IUUC-Mlu-068181	Myotis lucifugus	73.79	0.00e+00	1928.00
IUUC-Nle-069758	Nomascus leucogenys	79.17	0.00e+00	1887.00
IUUC-Opr-070531	Ochotona princeps	73.27	0.00e+00	1238.00
IUUC-Ont-072014	Oreochromis niloticus	72.38	0.00e+00	1745.00
IUUC-Oan-073169	Ornithorhynchus anatinus	79.87	0.00e+00	1905.00
IUUC-Ocu-074050	Oryctolagus cuniculus	74.96	0.00e+00	1763.00
IUUC-Ola-086941	Oryzias latipes	76.50	0.00e+00	1447.00
IUUC-Oga-088796	Otolemur garnettii	75.43	0.00e+00	1935.00
IUUC-Oar-090445	Ovis aries	79.98	0.00e+00	1899.00
IUUC-Ptr-090846	Pan troglodytes	75.52	0.00e+00	1972.00
IUUC-Pan-091986	Papio anubis	75.67	0.00e+00	1977.00
IUUC-Psi-093805	Pelodiscus sinensis	79.33	0.00e+00	1947.00
IUUC-Pfo-097301	Poecilia formosa	68.42	0.00e+00	1768.00
IUUC-Pab-097662	Pongo abelii	77.08	0.00e+00	1956.00
IUUC-Pca-100755	Procavia capensis	61.55	4.00e-175	608.00
IUUC-Pva-102280	Pteropus vampyrus	68.52	0.00e+00	1739.00
IUUC-Rno-105547	Rattus norvegicus	77.43	0.00e+00	1915.00
IUUC-Sha-106859	Sarcophilus harrisii	79.55	0.00e+00	1885.00
IUUC-Sar-113714	Sorex araneus	68.37	0.00e+00	1551.00
IUUC-Tgu-117116	Taeniopygia guttata	77.86	0.00e+00	1888.00
IUUC-Tru-118088	Takifugu rubripes	71.83	0.00e+00	1774.00
IUUC-Tsy-119616	Tarsius syrichta	76.07	0.00e+00	1639.00
IUUC-Tni-120284	Tetraodon nigroviridis	68.87	0.00e+00	1727.00
IUUC-Tbe-127900	Tupaia belangeri	83.37	0.00e+00	759.00
IUUC-Ttr-128294	Tursiops truncatus	68.09	0.00e+00	1658.00
IUUC-Vpa-130470	Vicugna pacos	70.63	0.00e+00	1653.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence