iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Rno-105680

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

MALT1 paracaspase

Genbank Nucleotide ID

AABR07032326

Gene Name

Malt1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000017181.8	ENSRNOT00000068418.4	ENSRNOP00000059281.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	88.65	0.00e+00	1302.00	IUUC-Hsa-046966

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MGEKGCTVPE LSDFLQALEH TEVLQLLNPP GLKITVNPES KAVLAGQFVK LCCRATGHPF 60
VQYQWFKMNK EIPYGNSSEL IFNTVHVKDA GFYVCRVNNN STFEFSQWSQ LDVCDVTEVS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCGAGAGCT TGGACCGCGC GCCGGAGGGC CGGGGCTGGC GGCAGCTGGC CGAGCTGGCG 60
GGCAGTCGGG GACGCCTTCG GCTCAGGTGA GCGGGACCCT CAGGCGGGCG GAGGGGTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR029030--Caspase-like_dom
IPR007110--Ig-like_dom
IPR013783--Ig-like_fold
IPR003599--Ig_sub
IPR003598--Ig_sub2
IPR033540--MALT1
IPR001309--Pept_C14_p20

PROSITE

PS50208--CASPASE_P20
PS50835--IG_LIKE

Pfam

PF13895--Ig_2

SMART

SM00409--IG
SM00408--IGc2

Gene Ontology

GO:0005829--C:cytosol
GO:0001650--C:fibrillar center
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0019209--F:kinase activator activity
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0001923--P:B-1 B cell differentiation
GO:0045087--P:innate immune response
GO:0051168--P:nuclear export
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032743--P:positive regulation of interleukin-2 production
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0050870--P:positive regulation of T cell activation
GO:0002726--P:positive regulation of T cell cytokine production
GO:0051259--P:protein oligomerization
GO:0042981--P:regulation of apoptotic process
GO:0050856--P:regulation of T cell receptor signaling pathway
GO:0009620--P:response to fungus
GO:0002237--P:response to molecule of bacterial origin
GO:0042098--P:T cell proliferation
GO:0050852--P:T cell receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003814	Anas platyrhynchos	68.24	0.00e+00	998.00
IUUC-Aca-005192	Anolis carolinensis	61.19	0.00e+00	719.00
IUUC-Ame-010608	Astyanax mexicanus	54.14	0.00e+00	738.00
IUUC-Bta-012436	Bos taurus	86.26	0.00e+00	1266.00
IUUC-Cel-018688	Caenorhabditis elegans	26.45	2.00e-42	167.00
IUUC-Cja-018945	Callithrix jacchus	76.86	0.00e+00	1071.00
IUUC-Cfa-020245	Canis familiaris	88.81	0.00e+00	1313.00
IUUC-Cpo-022400	Cavia porcellus	88.03	0.00e+00	1295.00
IUUC-Csa-023556	Chlorocebus sabaeus	88.37	0.00e+00	1277.00
IUUC-Cho-024489	Choloepus hoffmanni	84.21	5.00e-125	442.00
IUUC-Csv-026274	Ciona savignyi	28.77	9.00e-09	53.90
IUUC-Dre-028666	Danio rerio	53.36	0.00e+00	711.00
IUUC-Dno-029397	Dasypus novemcinctus	87.31	0.00e+00	1285.00
IUUC-Ete-032600	Echinops telfairi	62.54	2.00e-108	386.00
IUUC-Eca-033475	Equus caballus	88.80	0.00e+00	1313.00
IUUC-Eeu-034788	Erinaceus europaeus	84.02	0.00e+00	1233.00
IUUC-Fca-035687	Felis catus	86.68	0.00e+00	1264.00
IUUC-Fal-037432	Ficedula albicollis	66.11	0.00e+00	952.00
IUUC-Gmo-038533	Gadus morhua	52.05	0.00e+00	633.00
IUUC-Gga-040429	Gallus gallus	68.74	0.00e+00	999.00
IUUC-Gac-041963	Gasterosteus aculeatus	58.07	0.00e+00	769.00
IUUC-Ggo-045328	Gorilla gorilla	88.37	0.00e+00	1271.00
IUUC-Hsa-046966	Homo sapiens	88.65	0.00e+00	1276.00
IUUC-Itr-048424	Ictidomys tridecemlineatus	92.78	0.00e+00	890.00
IUUC-Lch-049486	Latimeria chalumnae	65.63	0.00e+00	945.00
IUUC-Loc-051782	Lepisosteus oculatus	58.99	0.00e+00	811.00
IUUC-Laf-053612	Loxodonta africana	86.07	0.00e+00	1281.00
IUUC-Mcc-054811	Macaca mulatta	85.91	0.00e+00	1229.00
IUUC-Meu-056602	Macropus eugenii	89.77	2.00e-127	449.00
IUUC-Mmr-060713	Microcebus murinus	90.08	0.00e+00	1341.00
IUUC-Mdo-062385	Monodelphis domestica	78.23	0.00e+00	1143.00
IUUC-Mpu-065996	Mustela putorius furo	88.27	0.00e+00	1276.00
IUUC-Mlu-067627	Myotis lucifugus	86.41	0.00e+00	1231.00
IUUC-Nle-069583	Nomascus leucogenys	88.37	0.00e+00	1273.00
IUUC-Opr-070641	Ochotona princeps	83.69	0.00e+00	988.00
IUUC-Ont-071363	Oreochromis niloticus	57.83	0.00e+00	745.00
IUUC-Oan-073407	Ornithorhynchus anatinus	79.59	0.00e+00	726.00
IUUC-Ola-086554	Oryzias latipes	58.07	0.00e+00	734.00
IUUC-Oga-088538	Otolemur garnettii	81.28	0.00e+00	1144.00
IUUC-Oar-090012	Ovis aries	86.34	0.00e+00	1269.00
IUUC-Ptr-090677	Pan troglodytes	88.65	0.00e+00	1278.00
IUUC-Pan-092262	Papio anubis	88.37	0.00e+00	1275.00
IUUC-Psi-093186	Pelodiscus sinensis	69.02	0.00e+00	991.00
IUUC-Pfo-097154	Poecilia formosa	57.76	0.00e+00	725.00
IUUC-Pab-098695	Pongo abelii	82.22	0.00e+00	1157.00
IUUC-Pca-100956	Procavia capensis	93.25	0.00e+00	729.00
IUUC-Pva-102917	Pteropus vampyrus	79.17	0.00e+00	792.00
IUUC-Sha-107559	Sarcophilus harrisii	80.27	0.00e+00	1172.00
IUUC-Sar-113054	Sorex araneus	83.03	0.00e+00	713.00
IUUC-Ssc-116110	Sus scrofa	85.83	0.00e+00	1264.00
IUUC-Tgu-116542	Taeniopygia guttata	73.51	0.00e+00	937.00
IUUC-Tru-118019	Takifugu rubripes	56.57	0.00e+00	712.00
IUUC-Tsy-119591	Tarsius syrichta	76.78	0.00e+00	1043.00
IUUC-Tbe-128075	Tupaia belangeri	60.33	2.00e-107	383.00
IUUC-Ttr-128309	Tursiops truncatus	81.40	0.00e+00	1178.00
IUUC-Vpa-130271	Vicugna pacos	87.96	0.00e+00	895.00
IUUC-Xtr-132554	Xenopus tropicalis	61.33	0.00e+00	847.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence