iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-090733

Ensembl Protein ID

ENSPTRP00000001250.3

UniProt Accession

H2PZ06; H2PZ06_PANTR

Genbank Protein ID

JAA01763.1; JAA17806.1; JAA30587.1; JAA43328.1

Protein Name

Epidermal growth factor receptor pathway substrate 15

Genbank Nucleotide ID

AACZ03006722; GABF01004339; GABD01002513; GABE01001411

Gene Name

EPS15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000000729.6	ENSPTRT00000001379.3	ENSPTRP00000001250.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/DUIM	99.55	0.00e+00	1618.00	IUUC-Hsa-046286
UBD/Alpha-Helix/UIM	88.93	0.00e+00	1377.00	IUUC-Mmu-064091
UBD/Alpha-Helix/UBA	28.61	1.00e-34	143.00	IUUC-Sce-106303

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAAAAQLSLT QLSSGNSVYE KYYRQVDTGN TGRVLASDAA AFLKKSGLPD LILGKIWDLA 60
DTDGKGILNK QEFFVALRLV ACAQNGLEVS LSSLNLAVPP PRFHDTSSPL LISGTSAAEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCAGCCCG TCCTTCCTTC CCCTCCCTTG CATGATGGAA ACACCATGGC TGCGGCGGCC 60
CAGCTCTCTC TGACACAGGT AACGCCACAC GCCCGTCCGC CGGGCTTGGC CGGCCGGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0675--Receptor
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR003903--UIM_dom

PROSITE

PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50330--UIM

Pfam

PF12763--EF-hand_4

SMART

SM00054--EFh
SM00027--EH
SM00726--UIM

Gene Ontology

GO:0016235--C:aggresome
GO:0030122--C:AP-2 adaptor complex
GO:0060170--C:ciliary membrane
GO:0005829--C:cytosol
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005509--F:calcium ion binding
GO:0048268--P:clathrin coat assembly
GO:0006895--P:Golgi to endosome transport
GO:0019065--P:receptor-mediated endocytosis of virus by host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001596	Ailuropoda melanoleuca	92.51	0.00e+00	1420.00
IUUC-Apl-003288	Anas platyrhynchos	75.14	0.00e+00	1096.00
IUUC-Aca-005333	Anolis carolinensis	70.71	0.00e+00	1100.00
IUUC-Ago-007867	Ashbya gossypii	27.38	3.00e-31	130.00
IUUC-Acl-008193	Aspergillus clavatus	31.34	2.00e-22	101.00
IUUC-Afl-008603	Aspergillus flavus	30.75	2.00e-38	155.00
IUUC-Afu-008916	Aspergillus fumigatus	30.11	3.00e-40	160.00
IUUC-Ani-009469	Aspergillus nidulans	30.14	1.00e-40	162.00
IUUC-Ang-009642	Aspergillus niger	29.06	7.00e-37	149.00
IUUC-Aor-009997	Aspergillus oryzae	29.67	1.00e-37	152.00
IUUC-Ate-010517	Aspergillus terreus	29.95	1.00e-38	155.00
IUUC-Bta-013028	Bos taurus	91.63	0.00e+00	1465.00
IUUC-Bci-013666	Botrytis cinerea	30.05	9.00e-40	159.00
IUUC-Bol-015187	Brassica oleracea	38.04	7.00e-14	72.40
IUUC-Bra-017706	Brassica rapa	38.04	3.00e-13	71.20
IUUC-Cja-019821	Callithrix jacchus	95.32	0.00e+00	1588.00
IUUC-Cfa-021233	Canis familiaris	92.27	0.00e+00	1147.00
IUUC-Cpo-022339	Cavia porcellus	90.21	0.00e+00	1469.00
IUUC-Csa-024072	Chlorocebus sabaeus	97.73	0.00e+00	1529.00
IUUC-Cho-025000	Choloepus hoffmanni	74.32	0.00e+00	1127.00
IUUC-Csv-025925	Ciona savignyi	67.02	3.00e-34	137.00
IUUC-Cgl-026390	Colletotrichum gloeosporioides	24.22	4.00e-29	124.00
IUUC-Cme-027270	Cyanidioschyzon merolae	31.54	5.00e-20	92.80
IUUC-Dre-027504	Danio rerio	61.11	5.00e-171	595.00
IUUC-Dno-029498	Dasypus novemcinctus	87.09	0.00e+00	1391.00
IUUC-Dor-030630	Dipodomys ordii	88.63	0.00e+00	1419.00
IUUC-Dse-031409	Dothistroma septosporum	27.09	1.00e-33	139.00
IUUC-Ete-032737	Echinops telfairi	75.47	0.00e+00	1115.00
IUUC-Eca-033328	Equus caballus	93.47	0.00e+00	1463.00
IUUC-Eeu-035267	Erinaceus europaeus	82.75	0.00e+00	929.00
IUUC-Fca-035511	Felis catus	93.46	0.00e+00	1491.00
IUUC-Fal-036796	Ficedula albicollis	73.28	0.00e+00	1089.00
IUUC-Fox-037755	Fusarium oxysporum	29.77	4.00e-38	154.00
IUUC-Fso-038230	Fusarium solani	28.80	4.00e-40	160.00
IUUC-Gmo-038971	Gadus morhua	59.61	1.00e-167	583.00
IUUC-Ggr-039734	Gaeumannomyces graminis	27.84	9.00e-36	145.00
IUUC-Gga-040315	Gallus gallus	73.20	0.00e+00	1127.00
IUUC-Gac-042011	Gasterosteus aculeatus	52.73	0.00e+00	704.00
IUUC-Ggo-045493	Gorilla gorilla	93.16	0.00e+00	1505.00
IUUC-Hsa-046286	Homo sapiens	99.55	0.00e+00	1641.00
IUUC-Kpa-049396	Komagataella pastoris	32.05	2.00e-45	177.00
IUUC-Loc-052749	Lepisosteus oculatus	52.99	8.00e-163	567.00
IUUC-Lma-053198	Leptosphaeria maculans	28.86	1.00e-39	158.00
IUUC-Laf-054158	Loxodonta africana	90.70	0.00e+00	1435.00
IUUC-Mcc-055325	Macaca mulatta	98.19	0.00e+00	1580.00
IUUC-Mor-056953	Magnaporthe oryzae	30.58	1.00e-39	159.00
IUUC-Mtr-058311	Medicago truncatula	34.09	8.00e-15	76.30
IUUC-Mga-060058	Meleagris gallopavo	72.35	0.00e+00	1153.00
IUUC-Mvi-060354	Microbotryum violaceum	27.88	2.00e-31	131.00
IUUC-Mmr-061060	Microcebus murinus	94.36	0.00e+00	1508.00
IUUC-Mmu-064091	Mus musculus	88.93	0.00e+00	1270.00
IUUC-Mpu-065932	Mustela putorius furo	92.45	0.00e+00	1455.00
IUUC-Mlu-067488	Myotis lucifugus	90.47	0.00e+00	1452.00
IUUC-Nfi-068419	Neosartorya fischeri	30.28	5.00e-40	160.00
IUUC-Nle-068996	Nomascus leucogenys	98.87	0.00e+00	1585.00
IUUC-Opr-070750	Ochotona princeps	83.14	6.00e-140	491.00
IUUC-Ont-071424	Oreochromis niloticus	65.57	1.00e-158	553.00
IUUC-Oan-073457	Ornithorhynchus anatinus	66.84	0.00e+00	746.00
IUUC-Ocu-074535	Oryctolagus cuniculus	93.91	0.00e+00	1477.00
IUUC-Oba-075548	Oryza barthii	30.34	1.00e-13	72.40
IUUC-Ogl-077317	Oryza glaberrima	30.34	1.00e-13	72.40
IUUC-Ogu-078266	Oryza glumaepatula	30.34	1.00e-13	72.40
IUUC-Oin-079539	Oryza indica	30.34	1.00e-13	72.40
IUUC-Ome-081550	Oryza meridionalis	30.34	1.00e-13	72.40
IUUC-Oni-082418	Oryza nivara	30.34	1.00e-13	72.40
IUUC-Opu-084149	Oryza punctata	39.19	4.00e-13	70.90
IUUC-Oru-084223	Oryza rufipogon	35.29	2.00e-13	72.00
IUUC-Osa-085387	Oryza sativa	30.34	2.00e-13	71.60
IUUC-Ola-087107	Oryzias latipes	49.43	0.00e+00	637.00
IUUC-Oga-088532	Otolemur garnettii	90.82	0.00e+00	1458.00
IUUC-Oar-089833	Ovis aries	91.50	0.00e+00	1488.00
IUUC-Pan-092491	Papio anubis	93.43	0.00e+00	1445.00
IUUC-Psi-094063	Pelodiscus sinensis	75.56	0.00e+00	1163.00
IUUC-Pma-094451	Petromyzon marinus	55.75	5.00e-100	357.00
IUUC-Ppa-095176	Physcomitrella patens	35.79	3.00e-14	74.70
IUUC-Pab-098749	Pongo abelii	99.00	0.00e+00	1614.00
IUUC-Pop-099501	Populus trichocarpa	32.74	7.00e-13	69.70
IUUC-Pca-100378	Procavia capensis	77.28	0.00e+00	894.00
IUUC-Ppe-102036	Prunus persica	35.16	1.00e-12	69.30
IUUC-Pva-102739	Pteropus vampyrus	92.89	0.00e+00	1322.00
IUUC-Rno-105042	Rattus norvegicus	87.90	0.00e+00	1369.00
IUUC-Sce-106303	Saccharomyces cerevisiae	28.32	7.00e-35	143.00
IUUC-Sja-107675	Schizosaccharomyces japonicus	27.11	1.00e-34	142.00
IUUC-Spo-108370	Schizosaccharomyces pombe	26.76	5.00e-34	140.00
IUUC-Ssl-108463	Sclerotinia sclerotiorum	26.98	2.00e-35	144.00
IUUC-Smo-109013	Selaginella moellendorffii	41.30	2.00e-16	76.60
IUUC-Sit-110002	Setaria italica	23.19	2.00e-13	71.60
IUUC-Sly-111403	Solanum lycopersicum	32.52	5.00e-12	67.00
IUUC-Stu-112258	Solanum tuberosum	35.80	5.00e-10	59.30
IUUC-Sar-113358	Sorex araneus	74.41	0.00e+00	958.00
IUUC-Ssc-115746	Sus scrofa	90.97	0.00e+00	1439.00
IUUC-Tgu-117351	Taeniopygia guttata	73.17	0.00e+00	1088.00
IUUC-Tru-117870	Takifugu rubripes	56.36	0.00e+00	729.00
IUUC-Tsy-118873	Tarsius syrichta	84.10	0.00e+00	937.00
IUUC-Tni-120351	Tetraodon nigroviridis	56.97	0.00e+00	732.00
IUUC-Tca-121631	Theobroma cacao	45.45	2.00e-12	68.60
IUUC-Tre-122064	Trichoderma reesei	28.30	5.00e-34	140.00
IUUC-Tvi-122351	Trichoderma virens	28.65	5.00e-40	160.00
IUUC-Tbe-127307	Tupaia belangeri	91.00	0.00e+00	1386.00
IUUC-Ttr-128775	Tursiops truncatus	89.34	0.00e+00	1353.00
IUUC-Uma-129336	Ustilago maydis	29.86	3.00e-41	164.00
IUUC-Vda-129921	Verticillium dahliae	27.25	2.00e-31	131.00
IUUC-Vpa-130684	Vicugna pacos	86.76	0.00e+00	1395.00
IUUC-Xtr-132716	Xenopus tropicalis	58.57	0.00e+00	911.00
IUUC-Xma-133907	Xiphophorus maculatus	52.84	0.00e+00	667.00
IUUC-Yli-134577	Yarrowia lipolytica	28.70	3.00e-38	154.00
IUUC-Zma-135416	Zea mays	34.75	3.00e-14	74.70

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence