iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.50e-38	127.6	228	258
UBD/Beta-Prp	1.60e-53	181.9	296	431

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDl 30
           H++ +++++f  +d  +vsGsdDgt+++WD+
   Q: 228  HKEAIRGISFspTDSKFVSGSDDGTLRIWDF 258
           999********65599**************7 PP

UBD/Beta-Prp

   S: 33   tikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqc 128
            ik+wd ++g +l++l  h+++v ++k++++g++lvt+s+D+++k++d++  ++ v++++gh++++ s+s++p     + sG++d  i  w++ t+++
   Q: 296  PIKIWDPKSGIALATLHAHKSTVMDLKWNDNGNWLVTASRDHLLKLFDIRnLREEVQVFRGHKKEASSVSWHPiHEGLFCSGGSDGSILFWNVGTDKE 393
           59***********************************************945899******************666********************** PP
   S: 129  leetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl 166
           +  +++ hd++v+++++hp g +l sGs+D t+++W  
   Q: 394  IGCVETAHDSIVWTLAWHPLGHILCSGSNDHTIKFWTR 431
           **9*********************************87 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MDVSQPPPQL LTAPSALATN FTSLPPPNMG GQHYRHYHPH HGSNKHGYNQ FKPFMPGGFQ 60
RPFGMSQDDF DGKRLRKSVM RKTVDYNASI IKALENRLYQ RDYRDRLALQ PDSIYVPHML 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTATATATCG ATAACATTGC AATCGAAGCA CACGCTGGTG TCCGCGTTTC GTCGTGAATT 60
CCTCAAATTC GCGTTGTTCG GAAAGTTACT AGTTATTTGC AACGCGGCGA TTTGCAGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005847--C:mRNA cleavage and polyadenylation specificity factor complex
GO:0006379--P:mRNA cleavage
GO:0048812--P:neuron projection morphogenesis

KEGG

dme:Dmel_CG1109

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001064	Aegilops tauschii	52.74	4.00e-121	427.00
IUUC-Aml-001363	Ailuropoda melanoleuca	69.06	0.00e+00	663.00
IUUC-Atr-003030	Amborella trichopoda	54.62	5.00e-131	460.00
IUUC-Apl-003409	Anas platyrhynchos	68.75	0.00e+00	655.00
IUUC-Aca-004694	Anolis carolinensis	68.83	0.00e+00	658.00
IUUC-Aly-006063	Arabidopsis lyrata	51.95	7.00e-131	460.00
IUUC-Ath-006583	Arabidopsis thaliana	48.16	2.00e-125	442.00
IUUC-Ago-007805	Ashbya gossypii	42.25	2.00e-80	291.00
IUUC-Acl-008075	Aspergillus clavatus	37.86	2.00e-86	312.00
IUUC-Afl-008582	Aspergillus flavus	41.62	2.00e-84	305.00
IUUC-Afu-008817	Aspergillus fumigatus	40.45	6.00e-75	273.00
IUUC-Ani-009391	Aspergillus nidulans	37.86	1.00e-78	286.00
IUUC-Ang-009750	Aspergillus niger	41.49	3.00e-75	274.00
IUUC-Aor-010085	Aspergillus oryzae	39.48	1.00e-88	319.00
IUUC-Ate-010397	Aspergillus terreus	39.24	4.00e-88	318.00
IUUC-Ame-010741	Astyanax mexicanus	47.93	6.00e-114	404.00
IUUC-Bgr-012169	Blumeria graminis	44.74	4.00e-93	334.00
IUUC-Bta-013265	Bos taurus	69.06	0.00e+00	662.00
IUUC-Bci-013762	Botrytis cinerea	43.39	2.00e-98	352.00
IUUC-Bdi-014849	Brachypodium distachyon	51.80	2.00e-132	466.00
IUUC-Bol-015325	Brassica oleracea	52.29	3.00e-136	478.00
IUUC-Bra-017187	Brassica rapa	52.33	1.00e-135	476.00
IUUC-Cel-018378	Caenorhabditis elegans	51.09	3.00e-142	498.00
IUUC-Cja-019547	Callithrix jacchus	69.06	0.00e+00	663.00
IUUC-Cfa-020031	Canis familiaris	69.06	0.00e+00	662.00
IUUC-Cpo-021554	Cavia porcellus	69.39	0.00e+00	641.00
IUUC-Cre-022830	Chlamydomonas reinhardtii	40.98	2.00e-73	268.00
IUUC-Csa-023146	Chlorocebus sabaeus	68.83	0.00e+00	661.00
IUUC-Cho-024679	Choloepus hoffmanni	68.58	3.00e-171	595.00
IUUC-Cin-025415	Ciona intestinalis	58.92	6.00e-164	570.00
IUUC-Csv-026003	Ciona savignyi	57.88	4.00e-162	563.00
IUUC-Cgl-026391	Colletotrichum gloeosporioides	43.24	1.00e-93	336.00
IUUC-Cne-026983	Cryptococcus neoformans	42.75	8.00e-92	330.00
IUUC-Cme-027147	Cyanidioschyzon merolae	47.18	3.00e-115	407.00
IUUC-Dre-028545	Danio rerio	67.15	0.00e+00	681.00
IUUC-Dno-029677	Dasypus novemcinctus	68.75	0.00e+00	662.00
IUUC-Dse-031371	Dothistroma septosporum	40.15	2.00e-84	306.00
IUUC-Ete-032511	Echinops telfairi	60.99	2.00e-162	566.00
IUUC-Eca-034152	Equus caballus	69.06	0.00e+00	663.00
IUUC-Eeu-034560	Erinaceus europaeus	56.19	8.00e-66	244.00
IUUC-Fca-035820	Felis catus	69.06	0.00e+00	662.00
IUUC-Fox-037958	Fusarium oxysporum	42.25	4.00e-94	338.00
IUUC-Fso-038162	Fusarium solani	41.71	7.00e-93	333.00
IUUC-Gmo-039708	Gadus morhua	65.35	0.00e+00	660.00
IUUC-Ggr-040031	Gaeumannomyces graminis	39.44	3.00e-83	301.00
IUUC-Gga-040963	Gallus gallus	69.06	0.00e+00	660.00
IUUC-Gac-041541	Gasterosteus aculeatus	66.05	0.00e+00	658.00
IUUC-Gma-044352	Glycine max	50.56	5.00e-133	467.00
IUUC-Ggo-045564	Gorilla gorilla	68.75	0.00e+00	661.00
IUUC-Hsa-045833	Homo sapiens	69.06	0.00e+00	663.00
IUUC-Hvu-047848	Hordeum vulgare	56.87	9.00e-91	326.00
IUUC-Itr-048083	Ictidomys tridecemlineatus	69.06	0.00e+00	662.00
IUUC-Kpa-049308	Komagataella pastoris	40.58	3.00e-82	297.00
IUUC-Lch-050525	Latimeria chalumnae	65.59	0.00e+00	668.00
IUUC-Lpe-051364	Leersia perrieri	46.76	7.00e-119	420.00
IUUC-Loc-052696	Lepisosteus oculatus	69.55	0.00e+00	665.00
IUUC-Lma-052951	Leptosphaeria maculans	45.04	2.00e-96	345.00
IUUC-Laf-053653	Loxodonta africana	69.06	0.00e+00	660.00
IUUC-Mcc-055797	Macaca mulatta	69.06	0.00e+00	663.00
IUUC-Meu-056331	Macropus eugenii	70.69	2.00e-145	509.00
IUUC-Mor-057168	Magnaporthe oryzae	39.60	5.00e-89	321.00
IUUC-Mpo-057510	Magnaporthe poae	42.97	2.00e-61	228.00
IUUC-Mtr-058032	Medicago truncatula	55.09	4.00e-131	461.00
IUUC-Mla-058852	Melampsora laricipopulina	50.00	8.00e-113	399.00
IUUC-Mga-059311	Meleagris gallopavo	69.42	0.00e+00	658.00
IUUC-Mvi-060544	Microbotryum violaceum	51.73	3.00e-114	404.00
IUUC-Mmr-061143	Microcebus murinus	69.06	0.00e+00	662.00
IUUC-Mdo-061977	Monodelphis domestica	69.06	0.00e+00	660.00
IUUC-Mmu-063922	Mus musculus	69.06	0.00e+00	662.00
IUUC-Mac-064961	Musa acuminata	52.49	9.00e-138	483.00
IUUC-Mpu-066079	Mustela putorius furo	71.77	1.00e-169	590.00
IUUC-Mlu-067247	Myotis lucifugus	69.06	0.00e+00	663.00
IUUC-Nfi-068255	Neosartorya fischeri	41.67	1.00e-82	300.00
IUUC-Ncr-068909	Neurospora crassa	42.79	1.00e-96	346.00
IUUC-Nle-068994	Nomascus leucogenys	69.06	0.00e+00	663.00
IUUC-Opr-071079	Ochotona princeps	70.99	0.00e+00	659.00
IUUC-Ont-071971	Oreochromis niloticus	66.67	0.00e+00	674.00
IUUC-Oan-073135	Ornithorhynchus anatinus	70.03	5.00e-173	601.00
IUUC-Ocu-073982	Oryctolagus cuniculus	69.06	0.00e+00	660.00
IUUC-Oba-075297	Oryza barthii	52.52	2.00e-120	425.00
IUUC-Obr-076641	Oryza brachyantha	51.18	1.00e-129	456.00
IUUC-Ogl-077539	Oryza glaberrima	57.63	5.00e-92	330.00
IUUC-Ogu-078807	Oryza glumaepatula	52.52	2.00e-120	425.00
IUUC-Oin-079229	Oryza indica	55.97	8.00e-132	463.00
IUUC-Olo-080371	Oryza longistaminata	52.43	2.00e-117	415.00
IUUC-Ome-081149	Oryza meridionalis	52.52	7.00e-120	423.00
IUUC-Oni-082970	Oryza nivara	52.52	2.00e-120	425.00
IUUC-Opu-083415	Oryza punctata	51.43	1.00e-118	419.00
IUUC-Oru-085236	Oryza rufipogon	52.52	2.00e-120	426.00
IUUC-Ola-087421	Oryzias latipes	66.67	0.00e+00	676.00
IUUC-Olu-087821	Ostreococcus lucimarinus	46.99	3.00e-102	364.00
IUUC-Oga-088132	Otolemur garnettii	69.06	0.00e+00	662.00
IUUC-Oar-089513	Ovis aries	69.06	0.00e+00	662.00
IUUC-Ptr-090717	Pan troglodytes	69.06	0.00e+00	663.00
IUUC-Pan-092108	Papio anubis	69.06	0.00e+00	662.00
IUUC-Psi-093892	Pelodiscus sinensis	69.06	0.00e+00	659.00
IUUC-Pma-094561	Petromyzon marinus	66.60	0.00e+00	674.00
IUUC-Pno-094943	Phaeosphaeria nodorum	43.48	3.00e-98	351.00
IUUC-Ppa-095359	Physcomitrella patens	59.64	1.00e-143	502.00
IUUC-Pfo-096516	Poecilia formosa	65.49	0.00e+00	665.00
IUUC-Pab-097759	Pongo abelii	69.06	0.00e+00	663.00
IUUC-Pop-098892	Populus trichocarpa	56.88	1.00e-134	473.00
IUUC-Pca-100405	Procavia capensis	59.09	2.00e-27	117.00
IUUC-Ppe-101957	Prunus persica	56.65	2.00e-133	468.00
IUUC-Pva-102918	Pteropus vampyrus	69.28	0.00e+00	662.00
IUUC-Pgr-103594	Puccinia graminis	49.62	5.00e-115	407.00
IUUC-Ptt-103879	Puccinia triticina	52.47	4.00e-100	358.00
IUUC-Pte-104419	Pyrenophora teres	43.00	2.00e-98	352.00
IUUC-Pyt-104718	Pyrenophora triticirepentis	44.99	4.00e-96	344.00
IUUC-Rno-105838	Rattus norvegicus	69.06	0.00e+00	662.00
IUUC-Sce-106331	Saccharomyces cerevisiae	40.38	1.00e-76	279.00
IUUC-Sha-107435	Sarcophilus harrisii	68.75	0.00e+00	656.00
IUUC-Sja-107796	Schizosaccharomyces japonicus	41.58	6.00e-95	340.00
IUUC-Spo-108163	Schizosaccharomyces pombe	42.60	5.00e-98	350.00
IUUC-Smo-109602	Selaginella moellendorffii	53.88	8.00e-137	479.00
IUUC-Sit-109729	Setaria italica	57.03	1.00e-133	469.00
IUUC-Sly-111679	Solanum lycopersicum	54.67	4.00e-137	481.00
IUUC-Sar-113157	Sorex araneus	69.06	0.00e+00	662.00
IUUC-Sbi-114853	Sorghum bicolor	50.89	2.00e-134	472.00
IUUC-Sre-115085	Sporisorium reilianum	41.97	4.00e-105	374.00
IUUC-Ssc-116286	Sus scrofa	68.90	0.00e+00	660.00
IUUC-Tgu-117219	Taeniopygia guttata	69.06	0.00e+00	659.00
IUUC-Tru-117550	Takifugu rubripes	66.67	0.00e+00	676.00
IUUC-Tsy-119294	Tarsius syrichta	69.06	0.00e+00	664.00
IUUC-Tni-120561	Tetraodon nigroviridis	66.32	0.00e+00	678.00
IUUC-Tca-121347	Theobroma cacao	49.89	8.00e-135	473.00
IUUC-Tre-122018	Trichoderma reesei	42.93	2.00e-96	345.00
IUUC-Tvi-122413	Trichoderma virens	42.43	1.00e-94	339.00
IUUC-Tae-123191	Triticum aestivum	55.35	1.00e-131	463.00
IUUC-Tme-127077	Tuber melanosporum	46.35	2.00e-100	359.00
IUUC-Tbe-127744	Tupaia belangeri	52.86	7.00e-105	375.00
IUUC-Ttr-128777	Tursiops truncatus	59.64	1.00e-154	540.00
IUUC-Uma-129568	Ustilago maydis	42.98	4.00e-103	367.00
IUUC-Vda-129834	Verticillium dahliae	40.00	5.00e-92	330.00
IUUC-Vpa-130563	Vicugna pacos	70.00	1.00e-45	177.00
IUUC-Vvi-131360	Vitis vinifera	50.00	1.00e-135	476.00
IUUC-Xtr-132630	Xenopus tropicalis	73.17	0.00e+00	664.00
IUUC-Xma-133665	Xiphophorus maculatus	66.04	0.00e+00	673.00
IUUC-Yli-134556	Yarrowia lipolytica	40.64	4.00e-88	318.00
IUUC-Zma-135787	Zea mays	52.53	4.00e-136	477.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence