iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094416

UUCD1 version

UUC-PeM-00431

Ensembl Protein ID

ENSPMAP00000005496.1

UniProt Accession

S4RJW3; S4RJW3_PETMA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000004971.1	ENSPMAT00000005516.1	ENSPMAP00000005496.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.60e-57	193.5	510	833

Active Site

Position(s)	Description	Evidence
806	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 7    krle.vefvgEegldlgGvtreflallskelqnpd......lglf....lysen..dketlqpnpdsglknpehlklFeflGrllgkal 82
           ++++ + f+ E   d+gG +re l+ +++el+ +d      +++f     +s +  +++ + pnpd      + l +F+++G+++g al
   Q: 510  SQWWsCDFTLEGMNDAGGGQRECLSDIAEELCPSDpycpvpVPFFlrmlGRSTGgqESCVYVPNPDC-----RDLYMFTWIGKIMGAAL 593
           567779*****************************99999955555544444441255555566655.....89*************** PP
   S: 83   qdgrlldlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNke 171
           +  ++l l l+  ++k+l+g+ ++++d+ +vd++l++sl +++e a+ +   ++l  +  +  + l++ +++eL+pgG  ++V + ++ 
   Q: 594  RGANILILCLPALVWKQLVGETVTWSDFRSVDETLARSLRSLEEAAD-EAAFAQLFGEELTYATTLSSGRTVELVPGGVWVRVHYGDRL 681
           *******************************************9954.4444444333335566799999999**************** PP
   S: 172  eYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefssee 260
           +Y +lv e+rl+e  ++qvea+r+G+ +v+p+++++l+t++e+e +++Ge+ei+++ lk+ ++    + + +  ++ ++e+l++fs+e+
   Q: 682  RYARLVQEARLCE-SRQQVEAIRKGIFSVVPQHIVNLLTWQEMERIVSGEAEITMDVLKRSITS--VMDNGEARMKCLFEALSNFSNED 767
           *************.99********************************************7644..46889999*************** PP
   S: 261  rkafLqFvTgssrlPlgGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetk 331
           r+ fL+FvTg+sr P+  ++ ++ +     ++++ d lP+ + C n+L LP+Yss ++++ekL +A+ +++
   Q: 768  RRLFLRFVTGRSRPPI-TIQVMQSS----MDSNKSDVLPETSLCSNTLILPNYSSAKVCEEKLHFAMYNCT 833
           *************997.66666622....334678********************************9985 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

RVRLARIRCV LESVRCFRDG LPLPEPLCYV PREVAYMSVH QGDCAGPPDS KGPQPSSPLP 60
GDGVWDRPGP SSQAPATPPP RMVVPLALSE GALVRASGEQ YCDGTGAWAK VLQPELRKLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTGTGAGGC TGGCCAGGAT CCGGTGTGTC CTGGAGAGCG TCCGGTGCTT CAGAGATGGC 60
CTGCCGCTGC CAGAACCGCT CTGCTACGTA CCGAGGGAGG TGGCCTACAT GAGTGTGCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR008979--Galactose-bd-like
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001229	Ailuropoda melanoleuca	38.81	3.00e-163	567.00
IUUC-Apl-003715	Anas platyrhynchos	41.84	3.00e-157	547.00
IUUC-Aca-004377	Anolis carolinensis	40.54	2.00e-177	614.00
IUUC-Ame-011918	Astyanax mexicanus	37.68	4.00e-159	553.00
IUUC-Bta-012736	Bos taurus	39.41	7.00e-165	573.00
IUUC-Cja-019926	Callithrix jacchus	39.65	1.00e-164	572.00
IUUC-Cfa-020753	Canis familiaris	41.81	3.00e-129	453.00
IUUC-Cpo-021415	Cavia porcellus	40.18	6.00e-164	570.00
IUUC-Csa-023096	Chlorocebus sabaeus	40.45	1.00e-164	572.00
IUUC-Dre-028746	Danio rerio	39.43	5.00e-161	560.00
IUUC-Dno-029293	Dasypus novemcinctus	42.94	6.00e-123	432.00
IUUC-Dor-031113	Dipodomys ordii	41.86	7.00e-135	472.00
IUUC-Ete-032601	Echinops telfairi	38.22	9.00e-143	499.00
IUUC-Eca-034198	Equus caballus	40.58	6.00e-164	569.00
IUUC-Eeu-034708	Erinaceus europaeus	45.62	7.00e-111	393.00
IUUC-Fca-035478	Felis catus	39.57	1.00e-165	575.00
IUUC-Fal-037366	Ficedula albicollis	40.70	2.00e-166	577.00
IUUC-Gmo-039020	Gadus morhua	39.88	3.00e-137	480.00
IUUC-Gga-040332	Gallus gallus	40.82	2.00e-175	608.00
IUUC-Gac-042336	Gasterosteus aculeatus	38.83	3.00e-168	584.00
IUUC-Ggo-045382	Gorilla gorilla	40.58	6.00e-166	576.00
IUUC-Hsa-046562	Homo sapiens	40.58	6.00e-166	576.00
IUUC-Itr-048208	Ictidomys tridecemlineatus	40.45	2.00e-164	571.00
IUUC-Lch-049606	Latimeria chalumnae	35.10	9.00e-103	365.00
IUUC-Loc-052448	Lepisosteus oculatus	36.02	5.00e-141	493.00
IUUC-Laf-054507	Loxodonta africana	39.13	7.00e-168	582.00
IUUC-Mcc-055690	Macaca mulatta	40.58	6.00e-166	576.00
IUUC-Meu-055970	Macropus eugenii	40.35	2.00e-160	558.00
IUUC-Mga-059654	Meleagris gallopavo	42.19	5.00e-157	546.00
IUUC-Mmr-061069	Microcebus murinus	40.31	1.00e-163	568.00
IUUC-Mdo-062547	Monodelphis domestica	47.62	3.00e-104	370.00
IUUC-Mmu-063096	Mus musculus	40.18	3.00e-164	570.00
IUUC-Mpu-065846	Mustela putorius furo	39.41	5.00e-164	570.00
IUUC-Mlu-067992	Myotis lucifugus	40.18	3.00e-162	564.00
IUUC-Nle-069565	Nomascus leucogenys	40.06	3.00e-148	517.00
IUUC-Opr-070853	Ochotona princeps	36.55	2.00e-95	342.00
IUUC-Ont-071628	Oreochromis niloticus	39.25	2.00e-162	565.00
IUUC-Ocu-074094	Oryctolagus cuniculus	40.71	5.00e-165	573.00
IUUC-Ola-087384	Oryzias latipes	39.46	6.00e-172	596.00
IUUC-Oga-088224	Otolemur garnettii	39.28	4.00e-165	573.00
IUUC-Oar-090043	Ovis aries	40.69	2.00e-155	541.00
IUUC-Ptr-090852	Pan troglodytes	40.58	5.00e-165	573.00
IUUC-Pan-092787	Papio anubis	40.92	5.00e-166	576.00
IUUC-Psi-092986	Pelodiscus sinensis	36.17	4.00e-115	407.00
IUUC-Pfo-096720	Poecilia formosa	39.53	2.00e-172	597.00
IUUC-Pab-098325	Pongo abelii	37.18	1.00e-108	385.00
IUUC-Pca-100885	Procavia capensis	35.19	9.00e-124	436.00
IUUC-Pva-102829	Pteropus vampyrus	31.58	1.00e-51	196.00
IUUC-Rno-104882	Rattus norvegicus	40.58	2.00e-165	574.00
IUUC-Sar-113020	Sorex araneus	40.87	9.00e-84	303.00
IUUC-Ssc-115436	Sus scrofa	31.56	3.00e-40	157.00
IUUC-Tgu-117042	Taeniopygia guttata	40.87	1.00e-175	608.00
IUUC-Tru-118419	Takifugu rubripes	38.48	1.00e-160	558.00
IUUC-Tsy-118829	Tarsius syrichta	34.94	1.00e-83	303.00
IUUC-Tni-120410	Tetraodon nigroviridis	32.59	4.00e-115	407.00
IUUC-Tbe-128113	Tupaia belangeri	45.71	3.00e-91	328.00
IUUC-Ttr-128167	Tursiops truncatus	37.11	8.00e-150	522.00
IUUC-Xtr-132910	Xenopus tropicalis	39.26	8.00e-155	539.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence