iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-125580

Ensembl Protein ID

TRIAE_CS42_1AS_TGACv1_020386_AA0077110.1

UniProt Accession

A0A1D5S4H5; A0A1D5S4H5_WHEAT

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_1AS_TGACv1_020386_AA0077110	TRIAE_CS42_1AS_TGACv1_020386_AA0077110.1	TRIAE_CS42_1AS_TGACv1_020386_AA0077110.1
TRIAE_CS42_1AS_TGACv1_020386_AA0077110	TRIAE_CS42_1AS_TGACv1_020386_AA0077110.2	TRIAE_CS42_1AS_TGACv1_020386_AA0077110.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.50e-106	358.1	517	857

Active Site

Position(s)	Description	Evidence
825	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp 65
           ++dlk  ++v+fv+     E+g+d gG++++f+++++++ ++ ++glf  +e+ ++ l+pnp sgl ++
   Q: 517  EEDLKGPIRVSFVNehgveEAGIDGGGIFKDFMENITRAAFDVQYGLF--KETVDHVLYPNPGSGLVHE 583
           6899**********9999888***************************..556688999********** PP
   S: 66   ehlklFeflGrllgkalqdgrlldlplsksfyklllgkklsledleevdpelykslkeikenaesdiee 134
           +hl++F+flG llgka+++g l+dlp++++f+++l +k+  l+dl+++dpely++l ++k++ + d+++
   Q: 584  QHLQYFHFLGSLLGKAMYEGILVDLPFATFFLSKLKEKSNFLNDLPSLDPELYRHLLFLKHY-KGDLSD 651
           **************************************9999********************.456666 PP
   S: 135  lgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfnevipl 203
             l+l f + ++++ge++eeeL+pgG++++Vtn+N   +++lv+++rl+ +i+ q  +f +Gf+++ip+
   Q: 652  --LELYFVIVNNEYGEQAEEELLPGGREMRVTNQNVITFIHLVANHRLNYQIRGQGRHFLRGFQKLIPK 718
           ..79999999*********************************************************** PP
   S: 204  ellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgs 271
           e++++F+e+e++lli+G+ e++d++dl+ +t+y ggy++d++ i+++wevl++fss+++k+fL+FvTg+
   Q: 719  EWIDMFNEHEIQLLISGSlESLDIDDLRLNTNYSGGYHPDHEIIDMLWEVLKSFSSDNQKKFLKFVTGC 787
           ********************************************************************* PP
   S: 272  srlPlgGfaelkprlfvirk......dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           sr Pl Gf++l p+ f+i++      +++ drlP+s TC+n+LkLP+Y +ke+l+ kLlyAi++++gF+
   Q: 788  SRGPLLGFEYLDPK-FCIQRagvpglEEHGDRLPTSATCMNLLKLPPYRTKEQLQTKLLYAINSEAGFD 855
           ************98.888888****88888**************************************9 PP
   S: 335  ls 336
           ls
   Q: 856  LS 857
           85 PP

Organism

Triticum aestivum

Protein Sequence
(Fasta)

MSVQSTSMPF VQLLETVACL INPKLPWNCK VVGYLQQKKI YCLFRGIISA VPQNARNMEH 60
CDISALEQVL MLTASHVGDN QCCCPAVDPR WSFSSQLLSI PFLWHRLPHF KKVFSANGLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTAAATCAGG AACTGCTTTG GCAATAATTC TGATTTTCTT CGCCAATTGC TGTTCTTCTT 60
CAATGCAAGT AAAGACAGTG ATATTGCTAT ACTTTCTCAA GTCTGCAGCT TACTTCTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007748	Ashbya gossypii	40.98	2.00e-74	275.00
IUUC-Ame-010769	Astyanax mexicanus	42.35	1.00e-73	272.00
IUUC-Cel-018447	Caenorhabditis elegans	33.17	2.00e-88	321.00
IUUC-Cfa-021031	Canis familiaris	47.06	4.00e-102	367.00
IUUC-Hvu-047770	Hordeum vulgare	99.46	0.00e+00	1497.00
IUUC-Mla-059124	Melampsora laricipopulina	44.36	2.00e-92	333.00
IUUC-Mac-065275	Musa acuminata	64.53	0.00e+00	1129.00
IUUC-Nfi-068280	Neosartorya fischeri	37.50	8.00e-73	270.00
IUUC-Pno-095132	Phaeosphaeria nodorum	36.11	1.00e-57	219.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	39.48	3.00e-81	297.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence