iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004498

UUCD1 version

UUC-AnC-00502

Ensembl Protein ID

ENSACAP00000002866.3

UniProt Accession

G1KBC6; G1KBC6_ANOCA

Protein Name

Uncharacterized protein

Gene Name

FBXO18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000002729.3	ENSACAT00000002937.3	ENSACAP00000002866.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	54.06	0.00e+00	951.00	IUUC-Hsa-046650
E3 adaptor/Cullin RING/SCF/F-box	29.43	6.00e-43	171.00	IUUC-Spo-108147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSVSNKIKTE EATDPPLSTD EDSCSLLEDY ESAPSTCPQA SHNSDQWEQD DDKSMLEGLL 60
ECPLGDGSVK REVDDTEVNL LPDVCFQLLR TASWEVPQGS INHMSASNRI KTEETADPPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGGCTTCT CCCTAGCAGA GCGTCAATAG GGTTTCGTTG CCAAGGAGAA GCAAGTTAGG 60
ATGAGCGCGC AAGACAGGAA GTGTTGATTT CTTCCAAGAT CAGAGTAAGT AGAAAGGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014017--DNA_helicase_UvrD-like_C
IPR000212--DNA_helicase_UvrD/REP
IPR001810--F-box_dom
IPR027417--P-loop_NTPase

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13361--UvrD_C

SMART

SM00256--FBOX

Gene Ontology

GO:0000785--C:chromatin
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0043138--F:3'-5' DNA helicase activity
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0015616--F:DNA translocase activity
GO:0003690--F:double-stranded DNA binding
GO:0003697--F:single-stranded DNA binding
GO:0008219--P:cell death
GO:0006974--P:cellular response to DNA damage stimulus
GO:0000737--P:DNA catabolic process, endonucleolytic
GO:0035562--P:negative regulation of chromatin binding
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0001934--P:positive regulation of protein phosphorylation
GO:0016567--P:protein ubiquitination
GO:0031297--P:replication fork processing
GO:0048478--P:replication fork protection
GO:0072429--P:response to intra-S DNA damage checkpoint signaling

KEGG

acs:100553441

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001396	Ailuropoda melanoleuca	54.13	0.00e+00	933.00
IUUC-Atr-002826	Amborella trichopoda	41.79	2.00e-03	38.50
IUUC-Apl-003317	Anas platyrhynchos	55.02	0.00e+00	936.00
IUUC-Ath-007293	Arabidopsis thaliana	40.91	3.00e-03	37.70
IUUC-Afl-008566	Aspergillus flavus	24.78	1.10e+00	29.30
IUUC-Ani-009226	Aspergillus nidulans	38.78	7.00e-03	36.60
IUUC-Ate-010526	Aspergillus terreus	42.86	3.00e-04	40.80
IUUC-Ame-011808	Astyanax mexicanus	55.08	3.00e-122	431.00
IUUC-Bta-013250	Bos taurus	53.85	0.00e+00	939.00
IUUC-Bol-015348	Brassica oleracea	34.17	5.00e-05	43.90
IUUC-Cja-019638	Callithrix jacchus	54.40	0.00e+00	956.00
IUUC-Cfa-020195	Canis familiaris	53.90	0.00e+00	963.00
IUUC-Cpo-022269	Cavia porcellus	53.36	0.00e+00	891.00
IUUC-Cre-022611	Chlamydomonas reinhardtii	45.83	7.00e-11	63.20
IUUC-Csa-024060	Chlorocebus sabaeus	54.06	0.00e+00	931.00
IUUC-Cho-025003	Choloepus hoffmanni	56.11	3.00e-128	452.00
IUUC-Cin-025694	Ciona intestinalis	26.90	2.00e-31	129.00
IUUC-Dre-028083	Danio rerio	46.91	0.00e+00	793.00
IUUC-Dno-029203	Dasypus novemcinctus	53.01	0.00e+00	870.00
IUUC-Dor-030477	Dipodomys ordii	61.28	1.00e-145	510.00
IUUC-Ete-032861	Echinops telfairi	54.97	0.00e+00	948.00
IUUC-Eca-033205	Equus caballus	54.63	0.00e+00	963.00
IUUC-Eeu-034784	Erinaceus europaeus	54.46	0.00e+00	756.00
IUUC-Fca-035797	Felis catus	50.30	0.00e+00	936.00
IUUC-Gmo-038855	Gadus morhua	44.05	1.00e-116	414.00
IUUC-Gga-040326	Gallus gallus	54.44	0.00e+00	996.00
IUUC-Gac-042240	Gasterosteus aculeatus	44.01	0.00e+00	679.00
IUUC-Ggo-045050	Gorilla gorilla	51.70	0.00e+00	873.00
IUUC-Hsa-046650	Homo sapiens	54.06	0.00e+00	931.00
IUUC-Itr-047965	Ictidomys tridecemlineatus	56.88	2.00e-131	461.00
IUUC-Lch-050231	Latimeria chalumnae	45.40	3.00e-137	482.00
IUUC-Lpe-051538	Leersia perrieri	39.58	6.80e-02	32.70
IUUC-Loc-051884	Lepisosteus oculatus	50.45	0.00e+00	874.00
IUUC-Lma-053267	Leptosphaeria maculans	24.53	5.00e-04	40.40
IUUC-Laf-053843	Loxodonta africana	54.86	0.00e+00	949.00
IUUC-Mcc-055570	Macaca mulatta	54.29	0.00e+00	957.00
IUUC-Meu-056798	Macropus eugenii	48.24	2.00e-104	373.00
IUUC-Mtr-057915	Medicago truncatula	37.88	3.00e-03	37.70
IUUC-Mla-059163	Melampsora laricipopulina	34.12	2.00e-05	42.40
IUUC-Mga-059648	Meleagris gallopavo	56.36	0.00e+00	942.00
IUUC-Mmr-060757	Microcebus murinus	54.40	0.00e+00	928.00
IUUC-Mdo-061913	Monodelphis domestica	52.42	0.00e+00	918.00
IUUC-Mmu-064337	Mus musculus	53.67	0.00e+00	948.00
IUUC-Mac-064479	Musa acuminata	42.42	3.00e-04	40.80
IUUC-Mpu-066483	Mustela putorius furo	54.57	0.00e+00	952.00
IUUC-Mlu-068204	Myotis lucifugus	52.00	0.00e+00	884.00
IUUC-Ncr-068735	Neurospora crassa	25.51	4.50e-02	33.90
IUUC-Nle-070053	Nomascus leucogenys	54.17	0.00e+00	929.00
IUUC-Opr-070588	Ochotona princeps	51.20	0.00e+00	887.00
IUUC-Ont-072655	Oreochromis niloticus	44.83	0.00e+00	691.00
IUUC-Oan-073351	Ornithorhynchus anatinus	54.97	0.00e+00	971.00
IUUC-Ocu-074465	Oryctolagus cuniculus	53.08	0.00e+00	895.00
IUUC-Obr-076710	Oryza brachyantha	34.88	5.00e-04	40.40
IUUC-Ogu-078184	Oryza glumaepatula	28.30	7.00e-03	37.00
IUUC-Oin-079176	Oryza indica	23.03	1.00e-04	41.20
IUUC-Ome-081984	Oryza meridionalis	39.22	2.10e-02	34.30
IUUC-Oni-082468	Oryza nivara	39.22	2.30e-02	34.30
IUUC-Opu-083155	Oryza punctata	50.00	1.00e-03	38.90
IUUC-Oru-085216	Oryza rufipogon	33.33	2.70e-02	35.00
IUUC-Olu-087831	Ostreococcus lucimarinus	34.24	1.00e-67	252.00
IUUC-Oga-089088	Otolemur garnettii	54.79	0.00e+00	921.00
IUUC-Oar-089870	Ovis aries	53.17	0.00e+00	929.00
IUUC-Ptr-090957	Pan troglodytes	54.57	0.00e+00	930.00
IUUC-Pan-092632	Papio anubis	54.00	0.00e+00	922.00
IUUC-Psi-093035	Pelodiscus sinensis	55.48	0.00e+00	1044.00
IUUC-Pno-094870	Phaeosphaeria nodorum	31.08	1.00e-03	38.50
IUUC-Pfo-096902	Poecilia formosa	42.99	0.00e+00	661.00
IUUC-Pab-098206	Pongo abelii	54.59	0.00e+00	889.00
IUUC-Pop-098801	Populus trichocarpa	33.00	9.00e-04	39.30
IUUC-Pca-100238	Procavia capensis	50.06	0.00e+00	855.00
IUUC-Ppe-101748	Prunus persica	34.72	1.00e-03	39.70
IUUC-Pva-103182	Pteropus vampyrus	54.44	0.00e+00	916.00
IUUC-Pte-104033	Pyrenophora teres	29.73	1.00e-03	38.90
IUUC-Pyt-104599	Pyrenophora triticirepentis	29.73	7.00e-04	39.30
IUUC-Rno-105141	Rattus norvegicus	53.90	0.00e+00	952.00
IUUC-Sce-106341	Saccharomyces cerevisiae	28.89	9.00e-05	42.00
IUUC-Sha-106827	Sarcophilus harrisii	51.64	0.00e+00	925.00
IUUC-Sja-107882	Schizosaccharomyces japonicus	28.87	3.00e-42	166.00
IUUC-Spo-108147	Schizosaccharomyces pombe	29.43	2.00e-43	170.00
IUUC-Ssl-108584	Sclerotinia sclerotiorum	30.86	2.00e-04	41.60
IUUC-Sly-111170	Solanum lycopersicum	34.02	1.10e-02	35.00
IUUC-Sbi-113981	Sorghum bicolor	31.15	5.50e-02	33.10
IUUC-Sre-115025	Sporisorium reilianum	34.07	4.00e-43	170.00
IUUC-Ssc-116188	Sus scrofa	57.94	0.00e+00	768.00
IUUC-Tgu-116612	Taeniopygia guttata	57.76	3.00e-165	574.00
IUUC-Tsy-119560	Tarsius syrichta	51.22	2.00e-68	254.00
IUUC-Tni-120734	Tetraodon nigroviridis	43.59	0.00e+00	665.00
IUUC-Tca-121338	Theobroma cacao	34.74	1.00e-03	38.90
IUUC-Tre-122089	Trichoderma reesei	37.04	7.00e-05	42.70
IUUC-Tvi-122403	Trichoderma virens	30.77	1.00e-03	38.90
IUUC-Tme-127009	Tuber melanosporum	29.55	4.00e-05	43.90
IUUC-Tbe-127431	Tupaia belangeri	54.99	0.00e+00	786.00
IUUC-Ttr-128744	Tursiops truncatus	49.39	0.00e+00	920.00
IUUC-Uma-129536	Ustilago maydis	35.02	9.00e-42	165.00
IUUC-Vda-129824	Verticillium dahliae	48.57	1.70e-01	30.40
IUUC-Vpa-130123	Vicugna pacos	79.73	5.00e-33	135.00
IUUC-Vvi-131025	Vitis vinifera	36.00	2.00e-03	38.10
IUUC-Xtr-132902	Xenopus tropicalis	52.83	0.00e+00	914.00
IUUC-Xma-133978	Xiphophorus maculatus	43.89	3.00e-149	522.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence