iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028821

UUCD1 version

UUC-DaR-00443

Ensembl Protein ID

ENSDARP00000141257.1

UniProt Accession

A0A0R4IZ86; A0A0R4IZ86_DANRE

Genbank Protein ID

ENSDARP00000141257

Protein Name

Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase

Genbank Nucleotide ID

AL954770

Gene Name

map3k1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000098405.1	ENSDART00000160345.1	ENSDARP00000141257.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	7.20e-15	55.8	424	477

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 1    ekvClvCgeggedekslveCek.CrewfHpaClklsveeelpnsekwiCpkCrs 53
           e++C++C   + de+sl++Ce+ Cr+++H++C+++++ee+++n++++iCp Cr+
   Q: 424  EQMCPICLLDMLDEESLTVCEEgCRNKLHHHCMSIWAEECRRNHDPLICPLCRA 477
           69**************************************************97 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MATAGSRTSS LGGLLDSSSG TNVGNGLQGT SNGSTSQNNS GKVKRNAGES SQWRRKVRSV 60
DLDKCESGTA ALHFLTVSGP GSIQTALLQQ SLADPPLGDK ISNNLCTSAQ EWMKSSLKSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAATTCAGGA CAGAAAATGG CGACGGCGGG GAGCCGGACG TCGTCGTTAG GCGGATTATT 60
AGACTCCAGT AGCGGCACAA ACGTCGGGAA CGGACTTCAA GGCACTTCCA ACGGCTCCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR007527--Znf_SWIM

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50089--ZF_RING_2
PS50966--ZF_SWIM

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004672--F:protein kinase activity
GO:0008270--F:zinc ion binding

KEGG

dre:100334486

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002233	Ailuropoda melanoleuca	71.10	0.00e+00	1731.00
IUUC-Apl-003550	Anas platyrhynchos	54.85	3.00e-51	194.00
IUUC-Aca-004258	Anolis carolinensis	71.62	0.00e+00	1693.00
IUUC-Ame-011412	Astyanax mexicanus	79.60	0.00e+00	1956.00
IUUC-Bta-013046	Bos taurus	69.43	0.00e+00	1716.00
IUUC-Cja-019060	Callithrix jacchus	70.79	0.00e+00	1718.00
IUUC-Cfa-020837	Canis familiaris	70.35	0.00e+00	1702.00
IUUC-Cpo-022141	Cavia porcellus	69.74	0.00e+00	1727.00
IUUC-Csa-023082	Chlorocebus sabaeus	70.77	0.00e+00	1716.00
IUUC-Cho-024597	Choloepus hoffmanni	78.57	9.00e-150	525.00
IUUC-Cin-025107	Ciona intestinalis	55.96	9.00e-59	219.00
IUUC-Csv-026034	Ciona savignyi	45.80	2.00e-132	467.00
IUUC-Dno-029178	Dasypus novemcinctus	70.33	0.00e+00	1724.00
IUUC-Dor-030534	Dipodomys ordii	71.18	0.00e+00	1721.00
IUUC-Ete-032843	Echinops telfairi	71.33	0.00e+00	1604.00
IUUC-Eca-033650	Equus caballus	68.71	0.00e+00	1653.00
IUUC-Eeu-034569	Erinaceus europaeus	80.18	3.00e-83	304.00
IUUC-Fca-035802	Felis catus	70.81	0.00e+00	1732.00
IUUC-Fal-037259	Ficedula albicollis	71.84	0.00e+00	1704.00
IUUC-Gga-040810	Gallus gallus	72.65	0.00e+00	1732.00
IUUC-Ggo-045102	Gorilla gorilla	70.76	0.00e+00	1720.00
IUUC-Hsa-045671	Homo sapiens	70.48	0.00e+00	1715.00
IUUC-Itr-048840	Ictidomys tridecemlineatus	69.48	0.00e+00	1344.00
IUUC-Lch-050377	Latimeria chalumnae	71.37	0.00e+00	1600.00
IUUC-Loc-052431	Lepisosteus oculatus	72.82	0.00e+00	1905.00
IUUC-Laf-053894	Loxodonta africana	69.53	0.00e+00	1698.00
IUUC-Mcc-055263	Macaca mulatta	71.01	0.00e+00	1722.00
IUUC-Meu-056425	Macropus eugenii	63.08	4.00e-140	493.00
IUUC-Mga-060098	Meleagris gallopavo	59.68	0.00e+00	1013.00
IUUC-Mmr-061686	Microcebus murinus	66.09	0.00e+00	1596.00
IUUC-Mdo-062008	Monodelphis domestica	72.80	0.00e+00	1727.00
IUUC-Mmu-063424	Mus musculus	70.82	0.00e+00	1753.00
IUUC-Mpu-066599	Mustela putorius furo	70.99	0.00e+00	1731.00
IUUC-Mlu-067383	Myotis lucifugus	69.77	0.00e+00	1615.00
IUUC-Nle-069023	Nomascus leucogenys	70.64	0.00e+00	1715.00
IUUC-Opr-070921	Ochotona princeps	65.69	0.00e+00	1206.00
IUUC-Oan-073487	Ornithorhynchus anatinus	72.01	0.00e+00	1774.00
IUUC-Ocu-074697	Oryctolagus cuniculus	71.20	0.00e+00	1734.00
IUUC-Oga-088673	Otolemur garnettii	70.15	0.00e+00	1707.00
IUUC-Oar-089502	Ovis aries	70.20	0.00e+00	1702.00
IUUC-Ptr-090480	Pan troglodytes	70.64	0.00e+00	1714.00
IUUC-Pan-092294	Papio anubis	70.92	0.00e+00	1722.00
IUUC-Psi-093454	Pelodiscus sinensis	92.71	5.00e-132	463.00
IUUC-Pma-094215	Petromyzon marinus	70.79	1.00e-149	523.00
IUUC-Pab-097948	Pongo abelii	70.57	0.00e+00	1706.00
IUUC-Pca-101118	Procavia capensis	67.89	0.00e+00	1501.00
IUUC-Pva-102761	Pteropus vampyrus	68.91	0.00e+00	1632.00
IUUC-Rno-105787	Rattus norvegicus	70.31	0.00e+00	1733.00
IUUC-Sha-106698	Sarcophilus harrisii	73.13	0.00e+00	1753.00
IUUC-Sar-113569	Sorex araneus	70.85	0.00e+00	1169.00
IUUC-Ssc-115862	Sus scrofa	70.30	0.00e+00	1734.00
IUUC-Tgu-117455	Taeniopygia guttata	71.59	0.00e+00	1699.00
IUUC-Tsy-119272	Tarsius syrichta	68.83	0.00e+00	1610.00
IUUC-Tbe-127403	Tupaia belangeri	64.08	0.00e+00	956.00
IUUC-Ttr-128576	Tursiops truncatus	68.86	0.00e+00	1629.00
IUUC-Vpa-130139	Vicugna pacos	70.64	0.00e+00	1726.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence